Cardiovascular, respiratory, and panic reactions to epinephrine in panic disorder patients

Biological Psychiatry

Volumn 41, Issue 2, 1997, Pages 249-251

  Van Zijderveld, Gudo A ^a   TenVoorde, Ben J ^a   Veltman, Dirk J ^a   Van Doornen, Lorenz J P ^a   Orlebeke, Jacob F ^a   Van Dyck, Richard ^a   Tilders, Fred J H ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

epinephrine; heart rate variability; hyperventilation; panic disorder; spectral analysis

Indexed keywords

ADRENALIN;

ADULT; ARTICLE; CARDIOVASCULAR EFFECT; CLINICAL ARTICLE; FEMALE; HUMAN; MALE; PANIC; PRIORITY JOURNAL; RESPIRATORY FUNCTION;

ADULT; AROUSAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROCARDIOGRAPHY; EPINEPHRINE; FEMALE; HEART RATE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; PANIC; PANIC DISORDER; RESPIRATION; SIGNAL PROCESSING, COMPUTER-ASSISTED;

EID: 0031040839     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(96)00421-0     Document Type: Article

References (23)

1. Akselrod S, Gordon D, Madwed JB, et al (1985): Hemodynamic regulation: Investigation by spectral analysis. Am J Physiol 249:H867-H875.
2. American Psychiatric Association (1987): Diagnostic and Statistical Manual of Mental Disorders, 3rd ed rev. Washington, DC: American Psychiatric Press.
3. Friedman BH, Thayer JF, Borkovec TD, et al (1993): Autonomic characteristics of nonclinical panic and blood phobia. Biol Psychiatry 34:298-310.
4. 2 J Psychophysiol 8:231-240.
5. George DT, Nutt DJ, Walker WV, et al (1989): Lactate and hyperventilation substantially attenuate vagal tone in normal volunteers. Arch Gen Psychiatry 46:153-156.
6. Kollai M, Kollai B (1992): Cardial vagal tone in generalised anxiety disorder. Br J Psychiatry 161:831-835.
7. Malliani A, Pagani M, Lombardi F, et al (1991): Cardiovascular neural regulation explored in the frequency domain. Circulation 84:482-492.
8. Middleton HC, Ashby M, Robbins TW (1994): Reduced plasma noradrenaline and abnormal heart rate variability in resting panic disorder patients. Biol Psychiatry 36:847-849.
9. Pagani M, Lombardi F, Guzetti S, et al (1986): Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympatho-vagal interaction in man and conscious dogs. Circ Res 59:178-193.
10. Papp LA, Gorman JM, Liebowitz MR, et al (1988): Epinephrine infusions in patients with social phobia. Am J Psychiatry 145:733-736.
11. Papp LA, Klein DF, Gorman JM (1993): Carbon dioxide hypersensitivity, hyperventilation, and panic disorder. Am J Psychiatry 150:1149-1157.
12. 2 Bull Eur Physiopathol Respira 23:9-13.
13. Pohl R, Yeragani VK, Balon R, et al (1990): Isoproterenol-induced panic: A β-adrenergic model of panic anxiety. In JC Ballenger (ed), Neuroblology of Panic Disorder. New York: Wiley-Liss v:pp107-120.
14. Pomeranz B, Macaulay RJB, Caudill MA (1985): Assessment of autonomic function in humans by heart rate spectral analysis. Am J Physiol 248:H151-H153.
15. Saul JP, Rea RF, Eckberg DL, et al (1990): Heart rate and muscle sympathetic nerve variability during reflex changes of autonomic activity. Am J Physiol 258:H713-H721.
16. Settels JJ, Wesseling KH (1985): FIN.A.PRES: Non-invasive finger arterial pressure waveform registration. In Orlebeke JF, Mulder G, van Doornen LJP (eds), The Psychophysiology of Cardiovascular Control. New York: Plenum Press, pp 267-283.
17. Sleight P, La Rovere M, Mortara A, et al (1995): Physiology and pathophysiology of heart rate and blood pressure variability in humans: Is power spectral analysis largely an index of baroreflex gain? Clin Sci 88:103-109.
18. Tulen JHM, Man in 't Veld AJ, van Roon AM, et al (1994): Spectral analysis of hemodynamics during infusions of epinephrine and norepinephrine in men. J Appl Physiol 76: 1914-1921.
19. van Zijderveld GA, van Doornen LJP, van Faassen I, et al (1992): The psychophysiological effects of adrenaline infusions as a function of trait anxiety and aerobic fitness. Anxiety Res 4:257-274.
20. van Zijderveld GA, van Doornen LJP, Orlebeke JF, et al (1993): Neurosomatism, adrenaline and mental performance. Biol Psychol 36:157-181.
21. Veltman DJ, van Zijderveld GA, van Dyck R (1996): Epinephrine infusions in panic disorder: A double blind placebo-controlled study. Journal of Affective Disorders 39:133-140.
22. Yeragani VK, Meiri PC, Pohl R, et al (1990a): Heart rate and blood pressure changes during postural change and isometric handgrip exercise in patients with panic disorder and normal controls. Acta Psychiatr Scand 81:9-13.
23. Yeragani VK, Balon R, Pohl R et al (1990b): Decreased R-R variance in panic disorder patients. Acta Psychiatr Scand 81:554-559.