The effect of pretreatment with a δ2-opioid receptor antisense oligodeoxynucleotide on the recovery from acute antinociceptive tolerance to δ2-opioid receptor agonist in the mouse spinal cord

British Journal of Pharmacology

Volumn 120, Issue 4, 1997, Pages 587-592

  Narita, Minoru ^a   Mizoguchi, Hirokazu ^a   Kampine, John P ^a   Tseng, Leon F ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

2 opioid receptor; Acute tolerance; Antinociception; Antisense oligodeoxynucleotide; Desensitization; Receptor turnover; Spinal cord

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; ANTISENSE OLIGODEOXYNUCLEOTIDE; DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR AGONIST; DELTORPHIN; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; KAPPA OPIATE RECEPTOR AGONIST; MESSENGER RNA; MU OPIATE RECEPTOR AGONIST; RECEPTOR SUBTYPE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG TOLERANCE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR DOWN REGULATION; SPINAL CORD;

3,4-DICHLORO-N-METHYL-N-(2-(1-PYRROLIDINYL)-CYCLOHEXYL)-BENZENEACETAMIDE, (TRANS)-ISOMER; ANALGESICS, OPIOID; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; ENKEPHALIN, LEUCINE; ENKEPHALINS; INJECTIONS, SPINAL; MALE; MICE; MICE, INBRED ICR; OLIGOPEPTIDES; PAIN MEASUREMENT; PYRROLIDINES; RECEPTORS, OPIOID, DELTA; RNA, ANTISENSE;

EID: 0031039918     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0700944     Document Type: Article

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