Comparative measurements of radiation-induced DNA double-strand breaks by graded voltage and pulsed-field gel electr0phoresis

International Journal of Radiation Biology

Volumn 71, Issue 1, 1997, Pages 95-100

  Zhou, P K ^a,b   Hendry, J H ^a   Margison, G P ^a  

^a CHRISTIE HOSPITAL   (United Kingdom)

^b BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DNA STRAND BREAKAGE; GAMMA RADIATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS;

DNA; DNA DAMAGE; ELECTROPHORESIS, GEL, PULSED-FIELD; HUMANS;

EID: 0031037871     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/095530097144463     Document Type: Article

References (14)

1. AGER, D. D., DEWEY, W. C., GARDINER, K., HARVEY, W., JOHNSON, R. T. and WALDERN, C. A., 1990, Measurement of radiation-induced DNA double-strand breaks by pulse-field gel electrophoresis. Radiation Research, 122, 181-187.
2. AGER, D. D. and DEWEY, W. C., 1990, Calibration of pulse-field gel electrophoresis for measurement of double-strand breaks. International Journal of Radiation Biology, 58, 249-259.
3. BLÖCHER, D., 1990, In CHEF electrophoresis a linear induction of dsb corresponds to a non-linear fraction of extracted DNA with dose. International Journal of Radiation Biology, 57, 7-12.
4. BLÖCHER, D. and KUHNI, M., 1990, DNA double-strand break analysis by CHEF electrophoresis. International Journal of Radiation Biology, 58, 23-34.
5. DAHM-DAPHI, J. and DIKOMEY, E., 1995, Separation of DNA fragments induced by ionizing irradiation using a graded-field gel electrophoresis. International Journal of Radiation Biology, 67, 161-168.
6. ELM, M. C., DELUCA, J. G. and BRADLEY, M. O., 1991, Significance of measurement of DNA double-strand breaks in mammalian cells. Pharmacology Theory, 51, 291-327.
7. FORAY, N., ARLET, C. F. and MALAISE, E. P., 1995, Dose-rate effect on induction and repair rate of radiation-induced DNA double-strand breaks in a normal and an ataxia telangiectasia human fibroblast cell line. Biochimie, 77, 900-905.
8. 125I decay. International Journal of Radiation Biology, 59, 343-357.
9. SMEETS, M. A., MOOREN, E. H. M. and BEGG, A. C., 1993, Radiation-induced DNA damage and repair in radiosensitive and radioresistant human tumour cells measured by field inversion gel electrophoresis. International Journal of Radiation Biology, 63, 703-714.
10. STAMATO, T. D. and DENKO, N., 1990, Asymmetric field inversion gel electrophoresis: a new method for detecting DNA double-strand breaks in mammalian cells. Radiation Research, 121, 196-205.
11. WHITAKER, S. J., UNG, Y. C. and MCMILLAN, T. J., 1995. DNA double-strand break induction and rejoining as determinants of human tumour cell radiosensitivity. A pulsed-field gel electrophoresis study. International Journal of Radiation Biology, 67, 7-8.
12. WLODEK, D., BANATH, J. and OLIVE, P. L., 1991, Comparison between pulsed-field and constant-field gel electrophoresis for measurement of DNA double-strand breaks in irradiated Chinese hamster ovary cells. International Journal of Radiation Biology, 60, 779-790.
13. WURM, R. E., BURNETT, N. G., DUGGAL, N., YARNOLD, J. R. and PEACOCK, J. H., 1994. Cellular radiosensitivity and DNA damage in primary human fibroblasts. International Journal of Radiation Oncology, Biology, Physics, 30, 625-633.
14. ZHOU, P. K. and WEI, K., 1991, Measurement of DNA double-strand breaks in mammalian cells after ionizing radiation by pulsed-field gel electrophoresis. Chinese Biochemical Journal, 7, 513-517.