Norepinephrine-induced lipolysis in rat fat cells from visceral and subcutaneous sites: Role of hormone-sensitive lipase and lipid droplets

Journal of Lipid Research

Volumn 38, Issue 1, 1997, Pages 132-138

  Morimoto, Chie ^a   Tsujita, Takahiro ^a   Okuda, Hiromichi ^a  

^a EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

basal lipolysis; phospholipid; site related difference

Indexed keywords

FAT DROPLET; NORADRENALIN; PHOSPHOLIPID; TRIACYLGLYCEROL LIPASE;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL FREE SYSTEM; HORMONE SENSITIVITY; LIPOLYSIS; MALE; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT;

ABDOMEN; ADIPOSE TISSUE; ANIMALS; CELL-FREE SYSTEM; CHOLESTEROL ESTERASE; FEMUR; LIPOLYSIS; LIPOSOMES; MALE; NOREPINEPHRINE; RATS; RATS, WISTAR; VISCERA;

EID: 0031037845     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Leibel, R. L., N. K. Edens, and S. K. Eried. 1989. Physiologic basis for the control of body fat distribution in humans. Annu. Rev. Nutr. 9: 417-443.
2. Vague, J. 1956. The degree of masculine differentiation of obesities: a factor determining predisposition to diabetes, atherosclerosis, gout and uric calculons diseases. Am. J. Clin. Nutr. 4: 20-34.
3. Björntorp, P. 1985. Adipose tissue in obesity (Willendorf lecture). Recent Adv. Obes. Res. 4: 163-170.
4. Arner, P., L. Hellström, H. Wahrenberg, and M. Bronnegard. 1990. Beta-adrenoceptor expression in human fat cells from different regions. J. Clin. Invest. 86: 1595-1600.
5. Mauriege, P., J. P. Despres, D. Prudhomme, M. C. Pouliot, M. Marcotte, A. Tremblay, and C. Bouchard. 1991. Regional variation in adipose tissue lipolylsis in lean and obese men. J. Lipid Res. 32: 1625-1633.
6. Lacasa, D., B. Agli, R. Pecquery, and Y. Giudicelli. 1991. Influence of ovariectomy and regional fat distribution on the membranous transducing system controlling lipolysis in rat fat cells. Endocrinology. 128: 747-753.
7. Crandall, D. L., B. M. Goldstein, F. Huggins, and P. Cervoni. 1984. Adipocyte blood flow: Influence of age, anatomic location and dietary manipulation. Am. J. Physiol. 247: R46-R51.
8. Lafontan, M., and M. Berlan. 1993. Fat cell adrenergic receptors and the control of white and brown fat cell function. J. Lipid Res. 34: 1057-1091.
9. Okuda, H., C. Morimoto, and T. Tsujita. 1994. Effect of substrates on the cyclic AMP-dependent lipolytic reaction of hormone-sensitive lipase. J. Lipid Res. 35: 1267-1273.
10. Ninomiya, H., C. Morimoto, T. Tsujita, M. Sumida, and H. Okuda. 1990. Biomodulator-mediated susceptibility of endogenous lipid droplets from rat adipocytes to hormone-sensitive lipase. Biochem. Med. Metab. Biol. 43: 112-127.
11. Blanchette-Mackie, E. J., N. K. Dwyer, T. Barber, R. A. Coxey, T. Takeda, C. M. Rondinone, J. L. Theodorakis, A. S. Greenberg, and C. Londos. 1995. Perilipin is located on the surface layer of intracellular lipid droplets in adipocytes. J. Lipid Res. 36: 1211-1226.
12. Okuda, H., C. Morimoto, and T. Tsujita. 1994. Role of endogenous lipid droplets in lipolysis in rat adipocytes. J. Lipid Res. 35: 36-44.
13. Chen, R. F. 1967. Removal of fatty acids from serum albumin by charcoal treatment. J. Biol. Chem. 242: 173-181.
14. Rodbell, M. 1964. Metabolism of isolated fat cells. J. Biol. Chem. 239: 375-380.
15. Okuda, H., T. Tsujita, and M. Kinutani. 1986. Studies on a protein kinase inhibitor-insensitive, phospholipase C-sensitive pathway of lipolysis in rat adipocytes. Pharmacol. Res. Commun. 18: 877-893.
16. Belfrage, P., and M. Vaughan. 1969. Simple liquid-liquid partition system for isolation of labeled oleic acid from mixtures with glycerides. J. Lipid Res. 10: 341-344.
17. Belfrage, R., C. Fredrikson, P. Strålfors, and H. Tornquist. 1984. Adipose tissue lipase. In Lipase. B. Borgström and H. L. Brockman, editors. Elsevier, Amsterdam. 365-416.
18. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head bacteriophage T4. Nature. 224: 1253-1258.
19. Sztalryd, C. and F. B. Kraemer. 1994. Differences in hormone-sensitive lipase expression in white adipose tissue from various anatomic locations of the rat. Metabolism. 43: 241-247.
20. Hamilton, J. G., and K. Comai. 1984. Separation of neutral lipids and free fatty acids by high-performance liquid chromatography using low wavelength ultraviolet detection. J. Lipid Res. 25: 1142-1148.
21. Bartlett, G. R. 1959. Phosphorus assay in column chromatography. J. Biol. Chem. 234: 466-468.