-
2
-
-
0026507547
-
-
J. M. Davidenko, A. V. Pertsov, R. Salomonsz, W. Baxter, J. Jalife, Nature 355, 349 (1992).
-
(1992)
Nature
, vol.355
, pp. 349
-
-
Davidenko, J.M.1
Pertsov, A.V.2
Salomonsz, R.3
Baxter, W.4
Jalife, J.5
-
5
-
-
0021914173
-
-
P. C. Ursell, P. I. Gardner, A. Albala, J. J. Fenoglio, A. L. Wit, ibid. 56, 436 (1985); J. H. Smith, C. R. Green, N. S. Peters, S. Rothery, N. J. Severs, Am. J. Pathol. 139, 801, (1991).
-
(1985)
Circ. Res.
, vol.56
, pp. 436
-
-
Ursell, P.C.1
Gardner, P.I.2
Albala, A.3
Fenoglio, J.J.4
Wit, A.L.5
-
6
-
-
0025941699
-
-
P. C. Ursell, P. I. Gardner, A. Albala, J. J. Fenoglio, A. L. Wit, ibid. 56, 436 (1985); J. H. Smith, C. R. Green, N. S. Peters, S. Rothery, N. J. Severs, Am. J. Pathol. 139, 801, (1991).
-
(1991)
Am. J. Pathol.
, vol.139
, pp. 801
-
-
Smith, J.H.1
Green, C.R.2
Peters, N.S.3
Rothery, S.4
Severs, N.J.5
-
8
-
-
0026098333
-
-
The patterns used in the experiments consisted of cell strands (25 to 70 μm wide and 1.8 mm long) connected to a large rectangular cell monolayer (2.2 by 2.2 mm). The preparations were mounted on an in verted microscope equipped for epifluorescence and were superfused with Hank's balanced salt solution (pH 7.40 at 36°C)
-
Geometrically defined patterns of cultured neonatal rat ventricular myocytes were obtained by means of a previously described method [S. Rohr, D. M. Schölly, A. G. Kléber, Circ. Res. 68, 114 (1991)]. The patterns used in the experiments consisted of cell strands (25 to 70 μm wide and 1.8 mm long) connected to a large rectangular cell monolayer (2.2 by 2.2 mm). The preparations were mounted on an in verted microscope equipped for epifluorescence and were superfused with Hank's balanced salt solution (pH 7.40 at 36°C).
-
(1991)
Circ. Res.
, vol.68
, pp. 114
-
-
Rohr, S.1
Schölly, D.M.2
Kléber, A.G.3
-
9
-
-
0029102366
-
-
The preparations were stained with the voltage-sensitive dye di-8-ANEPPS (Molecular Probes, Eugene, OR), and propagating action potentials were elicited at a basic cycle length of 500 ms with extracellular stimulation electrodes at a distance of >1 mm from the recording area. Changes in transmembrane voltage were monitored with a system for multiple site optical recording of transmembrane voltage with a total of 80 detectors. Optically recorded signals at a given site were normalized to signal amplitudes measured at the same site during control retrograde propagation. If an average action potential amplitude of 100 mV is assumed, the values of these normalized signals translate directly into millivolts. Activation times were determined from the time when the signal at a given site reached 50% of the full amplitude [S. Rohr, J. Cardiovasc. Electrophysiol. 6, 551 (1995)].
-
(1995)
J. Cardiovasc. Electrophysiol.
, vol.6
, pp. 551
-
-
Rohr, S.1
-
10
-
-
0028085535
-
-
S. Rohr and B. M. Salzberg, J. Gen. Physiol. 104, 287 (1994); V. G. Fast and A. G. Kléber, Cardiovasc. Res. 29, 697 (1995).
-
(1994)
J. Gen. Physiol.
, vol.104
, pp. 287
-
-
Rohr, S.1
Salzberg, B.M.2
-
11
-
-
0029061766
-
-
S. Rohr and B. M. Salzberg, J. Gen. Physiol. 104, 287 (1994); V. G. Fast and A. G. Kléber, Cardiovasc. Res. 29, 697 (1995).
-
(1995)
Cardiovasc. Res.
, vol.29
, pp. 697
-
-
Fast, V.G.1
Kléber, A.G.2
-
12
-
-
0024833716
-
-
The superfusion solution consisted of normal bath medium containing 10 μM palmitoleic acid (dispersed by ultrasonication) and 20 mM sucrose, which rendered the superfusion visible through birefringence
-
The superfusion of defined regions of the preparation was performed with a system described elsewhere [J. Streit and H. D. Lux, J. Neurosci. 9, 4190 (1989)]. The superfusion solution consisted of normal bath medium containing 10 μM palmitoleic acid (dispersed by ultrasonication) and 20 mM sucrose, which rendered the superfusion visible through birefringence.
-
(1989)
J. Neurosci.
, vol.9
, pp. 4190
-
-
Streit, J.1
Lux, H.D.2
-
13
-
-
0025762968
-
-
I. Miura, Y. Nasa, K. Ichihara, Y. Abiko, Clin. Exp. Pharmacol. Physiol. 18, 259 (1991).
-
(1991)
Clin. Exp. Pharmacol. Physiol.
, vol.18
, pp. 259
-
-
Miura, I.1
Nasa, Y.2
Ichihara, K.3
Abiko, Y.4
-
16
-
-
0028061307
-
-
C. Cabo et al., Circ. Res. 75, 1014 (1994).
-
(1994)
Circ. Res.
, vol.75
, pp. 1014
-
-
Cabo, C.1
-
19
-
-
15144351918
-
-
note
-
We thank R. Flückiger Labrada for preparing the heart cell cultures and H.-R. Lüscher, J. A. S. McGuigan, E. Niggli, A. L. Obaid, and J. S. Shiner for their helpful comments on the manuscript. Supported by the Swiss National Science Foundation and the Swiss Heart Foundation.
-
-
-
|