The impact of ethanol and marinol/marijuana usage on hiv+/aids patients undergoing azidothymidine, azidothymidine/dideoxycytidine, or dideoxyinosine therapy

Alcoholism: Clinical and Experimental Research

Volumn 21, Issue 1, 1997, Pages 122-127

  Whitfield, Robert M ^a   Bechtel, Lisa M ^a   Starich, Gale Hansen ^a,b  

^a INDIANA UNIVERSITY   (United States)

^b UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

Author keywords

AIDS; Antiretroviral Therapy; Ethanol; HIV+; Marinol Marijuana

Indexed keywords

AMYLASE; CANNABIS; DIDANOSINE; DRONABINOL; TRIACYLGLYCEROL LIPASE; ZALCITABINE; ZIDOVUDINE;

ACUTE PANCREATITIS; ALCOHOL CONSUMPTION; AMYLASE BLOOD LEVEL; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DRUG ABUSE; DRUG ALCOHOL INTERACTION; DRUG EFFICACY; FEMALE; HEALTH STATUS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LIVER FUNCTION TEST; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; TREATMENT OUTCOME;

CANNABIS; CANNABIS SATIVA; HUMAN IMMUNODEFICIENCY VIRUS;

EID: 0031037442     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1997.tb03739.x     Document Type: Article

References (20)

1. Fitterling JM, Matens PB, Scotti JR, Allen JS: AIDS risk behaviors and knowledge among heterosexual alcoholics and non-injecting drug users. Addiction 88:1257-1265, 1993
2. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, ed 4. Washington, D.C., American Psychiatric Association, 1994
3. Chen LH, Huang CY, Oslo Y, Fitzpatrick EA, Cohen DA: Effects of chronic alcohol feeding and murine AIDS virus infection on liver antioxidant defense systems in mice. Alcoholism 17:1022-1028, 1993
4. MacGregor RR: Alcohol and immune defense. JAMA 256:1474-1479, 1986
5. Jerrells TR, Marietta CA, Bone G, Weight FF, Sckhardt MJ: Ethanol-associated immunosuppression. Adv Biochem Psychopharmacol 44:173-185, 1988
6. Watson RR, Jackson JC, Hartmann B, Sampliner R, Mobley D, Eskelson C: Cellular immune functions, endorphins, and alcohol consumption in males. Alcohol Clin Exp Res 9:248-254, 1985
7. Nair MP, Kumar NM, Kronfol ZA, Saravolatz LA, Pottathil R, Greden JF, Schwartz SA: Selective effect of alcohol on cellular immune responses of lymphocytes from AIDS patients. Alcohol 11:85-90, 1994
8. Bagasra O, Balla AK, Lischner HW: Effects of alcohol ingestion on in vitro susceptibility of peripheral blood mononuclear cells to infection with HIV and of selected T cell functions. Alcohol Clin Exp Res 13:636-643, 1989
9. Grasela TH, Walawander CA, Beltangady M, Knupp CA, Martin RR, Dunkle LM, Barbhaiya RH, Pittman KA, Dolin R, Valentine FT, Leibman HA: Analysis of potential risk factors associated with the development of pancreatitis in phase I patients with AIDS or AIDS-related complex receiving didanosine. J Infect Dis 169:1250-1255, 1994
10. Seidlin M, Lambert JS, Dolin R, Valentine FT: Pancreatitis and pancreatic dysfunction in patients taking dideoxyinosine. AIDS 6:831-835, 1992
11. Knupp CA, Shyu WC, Dolin R: Pharmacokinetics of didanosine in patients with acquired immunodeficiency syndrome (AIDS) or AIDS related complex (ARC). Clin Pharmacol Ther 49:523-535, 1991
12. Drusano GL, Yuen GJ, Morse G: Impact of bioavailability on determination of the maximal tolerated dose of 2′,3′-dideoxyinosine in phase I trials. Antimicrob Agents Chemother 36:1280-1283, 1992
13. Maxon CJ, Greenfield SM, Turner JL: Acute pancreatitis as a common complication of 2′3′-dideoxyinosine therapy in the acquired immune deficiency syndrome. Am J Gastroenterol 87:708-713, 1992
14. Bernal A, del Junco G, Piot D: Acute pancreatitis in patients with AIDS. Proc 5th Int Confer on AIDS 333:000, 1989 (abstr)
15. Dowell S, Holt E, Myrphy FK: Pancreatitis associated with HIV infection. Proc 5th Int Confer on AIDS 235:000, 1989 (abstr)
16. Cederbaum AI: Role of lipid peroxidation and oxidative stress in alcohol toxicity. Free Radic Biol Med 7:537-539, 1989
17. Muller A, Sies H: Alcohol, aldehydes, and lipid peroxidation: Current notions. Alcohol 1(Suppl.):67-74, 1987
18. Fischer-Stenger K, Dove-Pettit DA, Cabral GA: Delta-9-tetrahydrocannabinol inhibition of tumor necrosis factor-alpha: Suppression of post-translational events. J Pharmacol Exp Ther 267:1558-1565, 1993
19. Burnette-Curley D, Marciano-Cabral F, Fischer-Stenger K, Cabral GA: Delta-9-tetrahydrocannabinol inhibits cell contact-dependent cytotoxicity of Bacillus Calmette-Guerin-activated macrophages. Int J Immunopharmacol 15:371-382, 1993
20. Cabral GA, Vasquez R: Effects of marijuana on macrophage function, in Friedman H, Specter S, Klein TW (eds): Drugs of Abuse, Immunity, and Immunodeficiency. New York, Plenum Press, 1991, pp 93-105