Mechanistic studies on phototoxicity induced by antibacterial quinolones

Toxic Substance Mechanisms

Volumn 16, Issue 1, 1997, Pages 81-86

  Vargas, Franklin ^a   Rivas, Carlos ^a  

^a INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

Author keywords

[No Author keywords available]

Indexed keywords

CINOXACIN; CIPROFLOXACIN; ENOXACIN; NALIDIXIC ACID; NORFLOXACIN; OFLOXACIN; OXOLINIC ACID; PIPEMIDIC ACID; QUINOLONE DERIVATIVE; ROSOXACIN;

ANIMAL EXPERIMENT; ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG DECOMPOSITION; DRUG STABILITY; MOUSE; NONHUMAN; PHOTODEGRADATION; PHOTOTOXICITY;

EID: 0031037326     PISSN: 10769188     EISSN: None     Source Type: Journal    
DOI: 10.1080/107691897229810     Document Type: Article

References (18)

1. Baran, R., and Juhlin, L. 1987. Drug-induced photo-onycholysis. Three subtypes identified in a study of 15 cases. J. Am. Acad. Dermatol. 17:1012-1016.
2. Bigley, D. and Alborno, A. 1982. Studies in decarboxylation. Part 15. The effect of 3-substitution on the rate of decarboxylation of β-unsaturated acids. J. Chem. Soc. Perkin Trans. 2:15.
3. Cárdenas, A. M., Vargas, F., Fernández, E., and Hidalgo, M. E. 1991. Phototoxic potential of quinolones. J. Photochem. Photobiol. B Biol. 10:249-255.
4. Detzer, N., and Huber, B. 1975. Photochimie heterocyclischer enone, I. Tetrahedron 31:1937-1941.
5. Ferguson, J., McIntosh, J., and Walker, E. M. 1988. Ciprofloxacin-induced photosensitivity: In vitro and in vivo studies. J. Invest. Dermatol. 91:385.
6. Hidalgo, M. E., Pessoa, C., Fernández, E., and Cárdenas, A. M. 1993. Comparative determination of photodegradation kinetics of quinolones. J. Photochem. Photobiol. A Chem. 73:135-138.
7. Kawabe, Y., Mizuno, N., and Sakakibara, S. 1989. Photoallergic reactions caused by enoxacin. Photodermatol. Photoimmunol. Photomed. 6:58-60.
8. Matsumoto, M., Kojima, K., Nagano, H., Matsubara, S., and Yokota, T. 1992. Photostability and biological activity of fluoroquinolones substituted at the 8 position after UV irradiation. Antimicrob. Agents Chemother. 36:1715-1719.
9. Petri, H., and Tronnier, H. 1986. Efficacy of enoxacin in the treatment of bacterial infections of the skin with regard to photosensitization. Infection 14(suppl. 3):213-216.
10. Przybilla, B., Georgii, A., Bergner, T., and Ring, J. 1990. Demonstration of quinolone phototoxicity in vitro. Dermatologica 181:98-103.
11. Shelley, E. D., and Shelley, W. B. 1988. The subcorneal pustular drug eruption: An example induced by norfloxacin, Cutis 42:24-27.
12. Vargas, F., Rivas, C., and Machado, R. 1991a. Decarboxylation and singlet oxygen production in the photolysis of nalidixic acid. J. Photochem. Photobiol. B Biol. 11:81-85.
13. Vargas, F., Rivas, C., Machado, R., and Miranda, M. A. 1991b. Photodegradation of nalidixic and tiaprofenic acid and of nifedipine in aerobic conditions. Photodermatol. Photoimmunol. Photomed. 8:218-221.
14. Vargas, F., Rivas, C., and Canudas, N. 1994. Photosensitized lipid peroxidation by cinoxacin and its photoproducts. Involvement of a derived peroxide in its phototoxicity. Pharmazie 49:742-745.
15. Vermeersch, G., Filali, A., Marko, A., Catteau, J. P., and Couture, A. 1989. Photo-CIDNP and ESR studies of a photosensitizing drug: Nalidixic acid. J. Photochem. Photobiol. B Biol. 4:85-89.
16. Wagai, N., and Tawara, K. 1991a. Quinoline antibacterial-agent-induced cutaneous phototoxicity ear swelling reactions in Balb/c mice. Toxicol. Lett. 52:215-223.
17. Wagai, N., and Tawara, K. 1991b. Important role of oxygen metabolites in quinolone antibacterial agent-induced cutaneous phototoxicity in mice. Arch. Toxicol. 65:495-499.
18. Wagai, N., Yamaguchi, M., Sekiguchi, M., and Tawara, K. 1990. Phototoxic potential of quinolone antibacterial agents in Balb/c mice. Toxicol. Lett. 54:299-308.