Melatonin - a chronobiotic and soporific hormone

Archives of Gerontology and Geriatrics

Volumn 24, Issue 2, 1997, Pages 167-173

  Haimov, Iris ^a   Lavie, Peretz ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

Melatonin; Pineal gland; Sleep wake regulation

Indexed keywords

MELATONIN;

AGING; CHRONOBIOLOGY; DROWSINESS; HUMAN; PINEAL BODY; PRIORITY JOURNAL; REVIEW; SLEEP DISORDER; SLEEP WAKING CYCLE; SUPRACHIASMATIC NUCLEUS;

EID: 0031036844     PISSN: 01674943     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4943(96)00749-2     Document Type: Article

References (26)

1. Aldhous, M., Franey, C, Wright, J. and Arendt, J. (1985): Plasma concentrations of melatonin in man following oral absorption of different preparations. Br. J. Clin. Pharmacol., 19, 517-521.
2. Anton-Tay, F., Diaz, J.L. and Fernandez-Guardiola, M. (1971): On the effects of melatonin upon human brain: its possible therapeutic implications. Life Sci., 10, 841-850.
3. Arendt, J.M., Borbely, A.A., Franey, C. and Wright. J. (1984): The effects of chronic, small doses of melatonin given in the late afternoon on fatigue in man: a preliminary study. Neurosci. Lett., 45, 317-321.
4. Etzioni, A., Luboshitzky, R., Tiosano, D., Ben-Harush, M., Goldsher, D., and Lavie, P. (1996): Melatonin replacement corrects sleep disturbances in a child with pineal tumor. Neurology, 46, 261-263.
5. Haimov, I., Laudon, M., Zisapel, N., Souroujon, M., Nof, D., Shlitner, A., Herer, P., Tzischinsky, O. and Lavie, P. (1994): Sleep disorders and metalonin rhythms in elderly people. Br. Med. J., 309, 167.
6. Haimov, I., Lavie, P., Laudon, M., Herer, P., Vigder, C. and Zisapel, N. (1995): Melatonin replacement therapy of elderly insomniacs. Sleep, 18, 598-603.
7. James, S.P., Mendelson, W.B., Sack, D.A., Rosenthal, N.E. and Wehr, T.E. (1987): The effects of melatonin on normal sleep. Neuropsychopharmacology, 1, 41-44.
8. James, S.P., Sack, D., Rosenthal, N. and Mendelson, W. (1990): Melatonin administration in insomnia. Neuropsychopharmacology, 3, 19-23.
9. Lavie, P. (1986): Ultrashort sleep-wake schedule III. 'Gates' and 'forbidden zones' for sleep. Electroencephalogr. Clin. Neurophysiol., 3, 414-425.
10. Lavie, P. and Zvuluni, A. (1992): The 24-h sleep propensity function (SPF): Experimental bases for somnotypology. Psychophysiology, 29, 566-575.
11. Lieberman, H.R., Waldhauser, F., Garfield, G., Lynch, H.J. and Wurtman, R.J. (1984): Effects of melatonin on human mood and performance. Brain Res. 323, 201-207.
12. Lynch, H.J., Wurtman, R.J., Moskowitz, M.A., Archer, M.C. and Ho, M.H. (1975): Daily rhythm in human urinary melatonin. Science, 187, 169-171.
13. MacFarlane, J.G., Cleghorn, J.M., Brown, G.M. and Streiner, D.L. (1991): The effects of exogenous melatonin on the total sleep time and daytime alertness of chronic insomniacs: a preliminary study. Biol. Psychiatry, 30, 371-376.
14. Moore, R.Y. and Card, J.P. (1985): Visual pathways and the entrainment of circadian rhythms. Ann. N.Y. Acad. Sci., 53, 123-133.
15. Nave, R., Peled, R. and Lavie, P. (1995) Melatonin improves evening napping. Eur. J. Pharmacol, 275, 213-216.
16. Reiter, R.J. (1980): The pineal and its hormones in the control of reproduction in mammals. Endocrinol. Rev., 11, 109-131.
17. Reiter, R.J. (1986): The pineal gland: an important link to the environment. News Physiol. Sci., l, 202-205.
18. Rusak, B. (1977): The role of the suprachiasmatic nuclei in the generation of circadian rhythms in the golden hamster, Mesocricetus auratus. J. Comp. Physiol., 118, 145-164.
19. Tzischinsky, O. and Lavie, P (1994): Melatonin possesses time-dependent hypnotic effects. Sleep, 17, 638-645.
20. Tzischinsky, O., Skene, D., Epstein, R. and Lavie, P. (1991): Circadian rhythms in 6-sulphatoxymelatonin and nocturnal sleep in blind children. Chronobiol. Int., 8, 168-175.
21. Tzischinsky, O., Pal, I., Epstein, R., Dagan, Y. and Lavie, P. (1992): The importance of timing in melatonin administration in a blind man. J. Pineal Res., 12, 105-108.
22. Tzischinsky, O., Dagan, Y. and Lavie, P. (1993a): The effects of melatonin on the timing of sleep in patients with delayed sleep phase syndrome. In: Melatonin and the Pineal Gland. From Basic Science to Clinical Application, pp. 351-354. Editors: Y. Touitou, J. Arendt and P. Pevet. Excerpta Medica, Amsterdam.
23. Tzischinsky, O., Shlitner, A. and Lavie, P. (1993b): The association between nocturnal sleep gates and nocturnal onset of urinary 6-sulfatoxy melatonin. J. Biol. Rhythms, 3, 199-209.
24. Utiger, R.D. (1992): Melatonin - the hormone of darkness. N. Engl. J. Med., 327, 1377-1379.
25. Vollrath, L., Semm, P. and Gammel, G. (1981): Sleep induction by intranasal application of melatonin. Adv. Biosci., 29, 327-329.
26. Waldhauser, F., Waldhauser, M., Lieberman, H.R., Deng, M.H., Lynch, H.J. and Wurtman, R.J. (1984): Bioavailability of melatonin in humans. Neuroendocrinology, 39, 307-313.