Identification of growth hormone-releasing hormone and somatostatin neurons projecting to the median eminence in normal and growth hormone-deficient ames dwarf mice

Neuroendocrinology

Volumn 65, Issue 2, 1997, Pages 107-116

  Romero, Mario I ^a   Phelps, Carol J ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Dwarf mouse; Growth hormone; Growth hormone releasing hormone; Immunocytochemistry; Somatostatin

Indexed keywords

FLUOROGOLD; GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; MESSENGER RNA; SOMATOSTATIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DWARFISM; FLUORESCENCE; GROWTH HORMONE DEFICIENCY; HYPOTHALAMUS; HYPOTHALAMUS PERIVENTRICULAR NUCLEUS; IMMUNOCYTOCHEMISTRY; INNERVATION; MEDIAN EMINENCE; MESSENGER RNA SYNTHESIS; MOUSE; NERVE CELL; NERVE FIBER; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; ULTRAVIOLET RADIATION;

ANIMALS; DWARFISM; GROWTH HORMONE-RELEASING HORMONE; IMMUNOHISTOCHEMISTRY; MEDIAN EMINENCE; MICE; MICE, MUTANT STRAINS; NEURONS; REFERENCE VALUES; SOMATOSTATIN; SYNAPTIC TRANSMISSION;

EID: 0031036814     PISSN: 00283835     EISSN: 14230194     Source Type: Journal    
DOI: 10.1159/000127170     Document Type: Article

References (45)

1. Frohman LA, Jansson J-O: Growth hormone-releasing hormone, Endocr Rev 1986:7:223-253.
2. Tannenbaum GS: Somatostatin as a physiological regulator of pulsatile growth hormone secretion, Horm Res 1988:29:70-74.
3. Niimi M, Takahara J, Sato M, Kawanishi K: Sites of origin of growth hormone-releasing factor-containing neurons projecting to the stalk-median eminence of the rat, Peptides 1989:10: 605-608.
4. Ishikawa K, Taniguchi Y, Kurosumi K, Suzuki M, Shinoda M: Immunohistochcmical identification of somatostatin-containing neurons projecting to the median eminence of the rat, Endocrinology 1987:121:94-97.
5. Kawano H, Daikoku S: Somatostatin-containing neuron systems in the rat hypothalamus: retrograde tracing and immunohistochemical studies, J Comp Neurol 1988:271:293-299.
6. Mechenthaler I, Sctalo G, Csontos C, Petrusz P, Flcrko B, Ncgro-Vilar: Combined retrograde tracing and immunocytochcmical identification of luteinizing hormone-releasing hormone and somatostatin-containing neurons projecting to the median eminence of the rat, Endocrinology 1989;125:2812-2821.
7. Chomczynski P, Downs TR, Frohman LA: Feedback regulation of growth hormone GHF rcleasing hormone gene expression by GH in rat hypothalamus, Mol Endocrinol 1988:2: 236-241.
8. DcGennaro Colonna V, Cattaneo E, Cocchi D, Müller EE, Maggi A: Growth hormone regulation of growth hormone-releasing hormone gene expression, Peptides 1988:9:985-988.
9. Zcitlcr P, Vician L, Chowcn-Brced JA, Argcnte J, Tannenbaum GS, Clifton DK, Steiner RA: Regulation of somatostatin and growth hormone-releasing hormone gene expression in the rat brain, Metabolism 1990:9(suppl 2):46-49.
10. Lanzi R, Tannenbaum GS: Time course and mechanism of growth hormone’s negative feedback effect on its own spontaneous release, Endocrinology 1992:130:780-788.
11. Aguila MC, McCann SM: Growth hormone increases somatostatin release and messenger ribonucleic acid levels in the rat hypothalamus, Brain Res 1993:623:89-94.
12. Rogers KV, Vician L, Steiner RA, Clifton DK: The effect of hypophvsectomy and growth hormone administration on pre-prosomaiostatin messenger ribonucleic acid in the periventricular nucleus of the rat hypothalamus, Endocrinology 1988:122:586-591.
13. Berelowitz M, Firestone SL, Frohman I, A: Effects of growth hormone excess and deficiency on hypothalamic somatostatin content and release and on tissue somatostatin distribution, Endocrinology 1981:109:714-719.
14. Chihara K, Minamitani N, Kaji H, Arimura A, Fujita T: Intraventricularly injected growth hormone stimulates somatostatin release into rat hypophysial portal blood, Endocrinology 1981;109:2279-2281.
15. Snell GD: Dwarf, a new Mendelian recessive character of the house mouse, Proc Natl Acad Sei USA 1929:15:733-734.
16. Eicher EM, Beamer WG: New mouse dw allele: Genetic location and effects on lifespan and growth hormone levels, J Hcrcd 1980:71:187-190.
17. Schaiblc R, Gowen JW: A new dw'arf mouse, Genetics 1961:46:896.
18. Behringer RR, Mathews LS, Palmiter RD, Brinstcr RL: Dwarf mice produced by genetic ablation of growth hormone-expressing cells, Genes Dev 1988:2:453-461.
19. Phelps CJ: Pituitary hormones as ncurotrophic signals: Anomalous hypophysiotrophic neuron differentiation in hypopituitarv dwarf mice, Proc Soc Exp Biol Med 1994;206:6-23.
20. Hurley DL, Phelps CJ: Altered growth hormone-releasing hormone mRNA expression in mice transgenic for excess or deficient endogenous growth hormone, Mol Cell Ncurosci 1993;4:237-244.
21. Phelps CJ, Dalcik H, Endo H, Talamantcs F, Hurley DL: Growth hormone-releasing hormone peptide and mRNA are overexprcssed in GH-dcficicnt Ames dwarf mice, Endocrinology 1993;133:3034-3037.
22. Fuhrmann G, Scala-Guenot DD, Ebel A: Somatostatin levels in the central nervous system of the Snell dwarf mouse: Is somatostatin excess the primary molecular defect in the dw/dw dwarfism? Brain Res 1985:328:161-164.
23. Webb SM, Lewinski AK, Stcgcr RW, Reiter RJ, Bartke A: Deficiency of immunoreactive somatostatin in the ME of Snell dwarf mice, LifcSci 1985:36:1239-1245.
24. Phelps CJ, Hoffman GE: Isolated deficiency of immunocytochcmically detected somatostatin in Snell dwarf, but not in’little’ mice, Peptides 1987;8:1127-1133.
25. Phelps CJ, Saleh MNMA, Romero Ml: Hypo-physiotropic somatostatin expression during postnatal development in growlh hormone-deficient Ames dwarf mice: Peptide immuno-cytochemistry, Neuroendocrinology 1996:64: 364-378.
26. O'Hara BF, Bendotti C, Reeves RH, Oster-Granite ML, Coyle JT, Gearhart JD: Genetic mapping and analysis of somatostatin expression in Snell dwarf mice, Brain Res 1988:464: 283-292.
27. Hurley DL, Wee BEF, Phelps CJ: Hypophvsio-tropic somatostatin expression during postnatal development in growth hormone-deficient Ames dwarf mice: mRNA in situ hybridization, Neuroendocrinology 1997:65:98-106.
28. Schmucd L, Fallon JH: Fluoro-gold: A new fluorescent retrograde axonal tracer with numerous unique properties, Brain Res 1986:377: 147-154.
29. Ambalavanar R, Morris R: Fluoro-gold injected either subcutaneously or imravascularlv results in extensive retrograde labing of CNS neurones having axons terminating outside the blood-brain-barrier, Brain Res 1989:505:171-175.
30. Slotnick BM, Leonard CM: A Stereotaxic Atlas of the Albino Mouse Forebrain, Rockville US Government Printing Office, Dept HEW, 1975.
31. Shaver SW, Pang JJ, Wainman DS, Wall KM, Gross PM: Morphology and function of capillary networks in subregions of the rat tuber cinerum, Cell Tissue Res 1992:267:437-448.
32. Banks WA, Broadwell RD: Blood to brain and brain to blood passage of native horseradish peroxidase, wheat germ agglutinin, and albumin: Pharmacokinetic and morphological assessments, J Neurochem 1994:62:2404-2419.
33. Merciicnthalcr I: Neurons with accesses to the general circulation in the central nervous system of the rat: A retrograde tracing study with fluoro-gold, Neuroscience 1991:44:655-662.
34. Watson RE Jr, Wicgand SJ, Clough RW, Hoffman GE: Use of cryoprotectant to maintain long-term peptide immunorcactivity and tissue morphology, Peptides 1986;7:155-159.
35. Endo H, Yamaguchi M, Fransworth R, Thor-darson G, Ogrcn L, Alonso FJ, Sakata M, Hiro-ta K, Talamantcs F: Mouse placental cells secrete immunoreactive growth hormone-releasing factor, Biol Reprod 1994:51:1206-1212.
36. Grumbach IM, Veh RW: The SA/rABC techniques: A new ABC procedure for detection of antigens at increased sensitivity, J Histochem Cytochem 1995:43:31-37.
37. Chang HT, Kuo H, Whittaker JA, Cooper NGF: Light and electron microscopic analysis of projection neurons rctrogradelv labeled with fluoro-gold: Notes on the application of antibodies to fluoro-gold, J Neurosci Methods 1990;35:31-37.
38. Konigsmark BW, Kalyanaraman WP, Corey P, Murphy EA: An evaluation of the techniques in neuronal poulation estimates: The Vlth nerve nucleus, Johns Hopkins Med J 1969:125:146-159.
39. Mcrchcnthalcr I, Arimura A: Effect of hypo-physcctomy on immunocytochcmically demonstrated growth hormone-releasing factor (GHRF) in the rat brain, Peptides 1985:6:865-867.
40. Ganzctti I, DcGennaro V, Redaelli M, Muller EE, Cocchi D: Effect of hypophyscctomy and growth hormone replacement on hypothalamic GHRH, Peptides 1986:7:1011-1014.
41. Katakami H, Downs TS, Frohman LA: Effect of hypophysectomy on hypothalamic growth hormone-releasing factor content and release in the rat, Endocrinology 1987:120:1079-1082.
42. Silverman AJ, Witkin JW, Silverman RC, Gibson MJ: Modulation of gonadotropin-releasing hormone by uptake of fluorogold from the vasculature, Synapse 1990;6:154-160.
43. Bartke A: Histology of the anterior hypophysis, thyroid and gonads of two types of dwarf mice, Anal Rec 1964;149:225-236.
44. Romero ML Phelps CJ: Prolactin replacement during development prevents the dopaminergic deficit in hypothalamic arcuate nucleus in prolactin-deficient Ames dwarf mice, Endocrinology 1993;133:1860-1870.
45. Phelps CJ, Romero MI: Postnatal decline in number of hypothalamic tuberoinfundibular dopaminergic (TIDA) neurons in prolactin-deficient mice: Correlation of the pattern with maternally-derived serum prolactin levels (abstract PI-681), Proc Meet Endocrine Soc, San Francisco, 1996.