-
1
-
-
0017378726
-
Biologic activity of A-ß-D-arabinofuranosyl-2-fluoroadenine, a metabolically stable analog of 9-ß-D-arabinofurosyladenine
-
Brockman RW, Schabel JR FM, Montgomery JA: Biologic activity of A-ß-D-arabinofuranosyl-2-fluoroadenine, a metabolically stable analog of 9-ß-D-arabinofurosyladenine. Biochem Pharmacol 26:2193-2196, 1977
-
(1977)
Biochem Pharmacol
, vol.26
, pp. 2193-2196
-
-
Brockman, R.W.1
Schabel F.M., Jr.2
Montgomery, J.A.3
-
2
-
-
0018885429
-
Comparison of the toxicity and metabolism of 9-ß-D-arabinofuranosyl-2-fluoroadenine and 9-ß-D-arabinofuranosyladenine in human lymphoblastoid cells
-
Plunkett W, Chubb S, Alexander L, et al.: Comparison of the toxicity and metabolism of 9-ß-D-arabinofuranosyl-2-fluoroadenine and 9-ß-D-arabinofuranosyladenine in human lymphoblastoid cells. Cancer Res 40:2349-2355, 1980
-
(1980)
Cancer Res
, vol.40
, pp. 2349-2355
-
-
Plunkett, W.1
Chubb, S.2
Alexander, L.3
-
3
-
-
0020058465
-
In vitro biological activity of 9-ß-D-arabinofuranosyl-2-fluoroadenine and the biochemical actions of its triphosphate on DNA polymerases and ribonucleotide reductase from HeLa cells
-
Tseng W-C, Derse D, Cheng Y-C, et al.: In vitro biological activity of 9-ß-D-arabinofuranosyl-2-fluoroadenine and the biochemical actions of its triphosphate on DNA polymerases and ribonucleotide reductase from HeLa cells. Mol Pharmacol 21:474-477, 1982
-
(1982)
Mol Pharmacol
, vol.21
, pp. 474-477
-
-
Tseng, W.-C.1
Derse, D.2
Cheng, Y.-C.3
-
4
-
-
0023733094
-
Interaction of 2-halogenated dATP analogs (F, Cl and Br) with human DNA polymerase. DNA primase and ribonucleotide reductase
-
Parker WB, Bapat AR, Shen JX, et al.: Interaction of 2-halogenated dATP analogs (F, Cl and Br) with human DNA polymerase. DNA primase and ribonucleotide reductase. Mol Pharmacol 34:485-491, 1988
-
(1988)
Mol Pharmacol
, vol.34
, pp. 485-491
-
-
Parker, W.B.1
Bapat, A.R.2
Shen, J.X.3
-
5
-
-
0025130572
-
Termination of DNA synthesis by 9-ß-D-arabinofuranosyl-2-fluoroadenine
-
Huang P, Chubb S, Plunkett W: Termination of DNA synthesis by 9-ß-D-arabinofuranosyl-2-fluoroadenine. J Biol Chem 265:16617-16625, 1990
-
(1990)
J Biol Chem
, vol.265
, pp. 16617-16625
-
-
Huang, P.1
Chubb, S.2
Plunkett, W.3
-
6
-
-
0027505303
-
Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2′-deoxyadenosine and 9-ß-D-arabinosyl fluoroadenine
-
Robertson LE, Chubb S, Meyn RE, et al.: Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2′-deoxyadenosine and 9-ß-D-arabinosyl fluoroadenine. Blood 81:143-150, 1993
-
(1993)
Blood
, vol.81
, pp. 143-150
-
-
Robertson, L.E.1
Chubb, S.2
Meyn, R.E.3
-
7
-
-
0027436016
-
Fludarabine: Pharmacokinetics, mechanisms of action, and rationales for combination therapies
-
Plunkett W, Gandhi V, Huang P, et al.: Fludarabine: Pharmacokinetics, mechanisms of action, and rationales for combination therapies. Semin Oncol 20:2-12, 1993 (suppl 7)
-
(1993)
Semin Oncol
, vol.20
, Issue.7 SUPPL.
, pp. 2-12
-
-
Plunkett, W.1
Gandhi, V.2
Huang, P.3
-
8
-
-
0018952812
-
Metabolism and chemotherapeutic activity of 9-ß-D-arabinofuranosyl-2-fluoroadenine against murine leukemia L1210 and evidence of its phosphorylation by deoxycytidine kinase
-
Brockman RW, Cheng YC, Schabel FM Jr, et al.: Metabolism and chemotherapeutic activity of 9-ß-D-arabinofuranosyl-2-fluoroadenine against murine leukemia L1210 and evidence of its phosphorylation by deoxycytidine kinase. Cancer Res 40:3610-3615, 1980
-
(1980)
Cancer Res
, vol.40
, pp. 3610-3615
-
-
Brockman, R.W.1
Cheng, Y.C.2
Schabel F.M., Jr.3
-
9
-
-
0020057077
-
Comparison of the actions of 9-ß-D-arabinofuranosyl-2-fluoroadenine and 9-ß-D-arabinofuranosyladenine on target enzymes from mouse tumor cells
-
White EL, Shaddix SC, Brockman RW, et al.: Comparison of the actions of 9-ß-D-arabinofuranosyl-2-fluoroadenine and 9-ß-D-arabinofuranosyladenine on target enzymes from mouse tumor cells. Cancer Res 42:2260-2264, 1982
-
(1982)
Cancer Res
, vol.42
, pp. 2260-2264
-
-
White, E.L.1
Shaddix, S.C.2
Brockman, R.W.3
-
10
-
-
0024268950
-
Cytotoxic activity of 9-ß-D-arabinofuranosyl-2-fluoroadenine 5′-monophosphate (fludarabine, NSC 312887) in a human tumor cloning system
-
Lathan B, Diehl V, Clark GM, et al.: Cytotoxic activity of 9-ß-D-arabinofuranosyl-2-fluoroadenine 5′-monophosphate (fludarabine, NSC 312887) in a human tumor cloning system. Eur J Cancer Clin Oncol 24:1891-1895, 1988
-
(1988)
Eur J Cancer Clin Oncol
, vol.24
, pp. 1891-1895
-
-
Lathan, B.1
Diehl, V.2
Clark, G.M.3
-
11
-
-
0021193453
-
Phase I clinical investigation of 9-ß-D-arabinofuranosyl-2-fluoroadenine 5′-monophosphate (NSC 312887), a new purine antimetabolite
-
Hutton JJ, Von Hoff DD, Kuhn J, et al.: Phase I clinical investigation of 9-ß-D-arabinofuranosyl-2-fluoroadenine 5′-monophosphate (NSC 312887), a new purine antimetabolite. Cancer Res 44:4183-4186, 1984
-
(1984)
Cancer Res
, vol.44
, pp. 4183-4186
-
-
Hutton, J.J.1
Von Hoff, D.D.2
Kuhn, J.3
-
12
-
-
0022651816
-
Phase I and II study of fludarabine phosphate in leukemia: Therapeutic efficacy with delayed central nervous system toxicity
-
Warrell RP, Berman E: Phase I and II study of fludarabine phosphate in leukemia: Therapeutic efficacy with delayed central nervous system toxicity. J Clin Oncol 4:74-79, 1986
-
(1986)
J Clin Oncol
, vol.4
, pp. 74-79
-
-
Warrell, R.P.1
Berman, E.2
-
13
-
-
0022980401
-
Fludarabine phosphate (NSC 312878) infusions for the treatment of acute leukemia: Phase I and neuropathological study
-
Spriggs DR, Stopa E, Mayer RJ, et al.: Fludarabine phosphate (NSC 312878) infusions for the treatment of acute leukemia: Phase I and neuropathological study. Cancer Res 46:5953-5958, 1986
-
(1986)
Cancer Res
, vol.46
, pp. 5953-5958
-
-
Spriggs, D.R.1
Stopa, E.2
Mayer, R.J.3
-
14
-
-
0024216099
-
Fludarabine monophosphate: A potentially useful agent in chronic lymphocytic leukemia
-
Grever MR, Kopecky KJ, Coltman CA, et al.: Fludarabine monophosphate: A potentially useful agent in chronic lymphocytic leukemia. Nouv Rev Fr Hematol 30:457-459, 1988
-
(1988)
Nouv Rev Fr Hematol
, vol.30
, pp. 457-459
-
-
Grever, M.R.1
Kopecky, K.J.2
Coltman, C.A.3
-
15
-
-
84871472387
-
-
Bethesda, MD, Investigational Drug Branch, Cancer Therapy Evaluation Program, Division of Cancer Treatment, Diagnosis and Centers, National Cancer Institute, National Institutes of Health (on file at CTEP)
-
Fludarabine: June 1995 Annual Report. Bethesda, MD, Investigational Drug Branch, Cancer Therapy Evaluation Program, Division of Cancer Treatment, Diagnosis and Centers, National Cancer Institute, National Institutes of Health (on file at CTEP)
-
Fludarabine: June 1995 Annual Report
-
-
-
16
-
-
0028120773
-
Fludarabine -Present status and future developments in chronic lymphocytic leukemia and lymphoma
-
Keating MJ, McLaughlin P, Plunkett W, et al.: Fludarabine -Present status and future developments in chronic lymphocytic leukemia and lymphoma. Ann Oncol 2:79-83, 1994 (suppl 5)
-
(1994)
Ann Oncol
, vol.2
, Issue.5 SUPPL.
, pp. 79-83
-
-
Keating, M.J.1
McLaughlin, P.2
Plunkett, W.3
-
17
-
-
0028073281
-
The expanding role of fludarabine in hematologic malignancies
-
Keating MJ, O'Brien S, Robertson LE, et al.: The expanding role of fludarabine in hematologic malignancies. Leuk Lymphoma 2:11-16, 1994 (suppl 14)
-
(1994)
Leuk Lymphoma
, vol.2
, Issue.14 SUPPL.
, pp. 11-16
-
-
Keating, M.J.1
O'Brien, S.2
Robertson, L.E.3
-
18
-
-
0027200169
-
Long-term follow-up of patients with chronic lymphocytic leukemia treated with fludarabine as a single agent
-
Keating MJ, O'Brien S, Kantarjian H, et al.: Long-term follow-up of patients with chronic lymphocytic leukemia treated with fludarabine as a single agent. Blood 81:2878-2884, 1993
-
(1993)
Blood
, vol.81
, pp. 2878-2884
-
-
Keating, M.J.1
O'Brien, S.2
Kantarjian, H.3
-
19
-
-
0342755133
-
Treatment of refractory chronic lymphocytic leukemia (CLL) with fludarabine monophosphate (FAMP) under the group C protocol
-
abstr 867
-
Sorensen JM, Vena D, Fallavollita A, et al.: Treatment of refractory chronic lymphocytic leukemia (CLL) with fludarabine monophosphate (FAMP) under the group C protocol. Proc Am Soc Clin Oncol 11:264, 1992 (abstr 867)
-
(1992)
Proc Am Soc Clin Oncol
, vol.11
, pp. 264
-
-
Sorensen, J.M.1
Vena, D.2
Fallavollita, A.3
-
20
-
-
0000087591
-
-
New York, NY, Alan R. Liss
-
Gale RP, Rai KR (eds): Chronic lymphocytic leukemia: Recent Progress and Future Directions. New York, NY, Alan R. Liss, 1987, pp 253-264
-
(1987)
Chronic Lymphocytic Leukemia: Recent Progress and Future Directions
, pp. 253-264
-
-
Gale, R.P.1
Rai, K.R.2
-
21
-
-
0003678252
-
-
Philadelphia, PA, Lippincott
-
MacDonald JS, Haller DG, Mayer RJ, et al. (eds): Manual of Oncologic Therapeutics (ed 3). Philadelphia, PA, Lippincott, 1995, p 525
-
(1995)
Manual of Oncologic Therapeutics (Ed 3)
, pp. 525
-
-
MacDonald, J.S.1
Haller, D.G.2
Mayer, R.J.3
-
22
-
-
0025166815
-
Tumor lysis syndrome complicating treatment of chronic lymphocytic leukemia with fludarabine phosphate
-
List AF, Kummet TD, Adams JD, et al.: Tumor lysis syndrome complicating treatment of chronic lymphocytic leukemia with fludarabine phosphate. Am J Med 89:388-390, 1991
-
(1991)
Am J Med
, vol.89
, pp. 388-390
-
-
List, A.F.1
Kummet, T.D.2
Adams, J.D.3
-
23
-
-
0343625348
-
Tumor lysis syndrome (TLS) in patients receiving fludarabine (F) for chronic lymphocytic leukemia (CLL)
-
abstr
-
Frame JN, Sorensen JM, Qashu N, et al.: Tumor lysis syndrome (TLS) in patients receiving fludarabine (F) for chronic lymphocytic leukemia (CLL). Proc Am Soc Hematol 82: 1993 (suppl 1, abstr)
-
(1993)
Proc Am Soc Hematol
, vol.82
, Issue.1 SUPPL.
-
-
Frame, J.N.1
Sorensen, J.M.2
Qashu, N.3
-
24
-
-
0023717101
-
Guidelines for clinical protocols for chronic lymphocytic leukemia: Recommendations of the National Cancer Institute-sponsored Working Group
-
Cheson BD, Bennett JM, Rai KR, et al.: Guidelines for clinical protocols for chronic lymphocytic leukemia: Recommendations of the National Cancer Institute-sponsored Working Group. Am J Hematol 29:152-163, 1988
-
(1988)
Am J Hematol
, vol.29
, pp. 152-163
-
-
Cheson, B.D.1
Bennett, J.M.2
Rai, K.R.3
-
25
-
-
33845382806
-
Nonparametric estimation from incomplete observations
-
Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457-481, 1958
-
(1958)
J Am Stat Assoc
, vol.53
, pp. 457-481
-
-
Kaplan, E.L.1
Meier, P.2
-
27
-
-
0013886333
-
Evaluation of survival data and two new rank order statistics arising in its consideration
-
Mantel N: Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother Rep 50:163-170, 1966
-
(1966)
Cancer Chemother Rep
, vol.50
, pp. 163-170
-
-
Mantel, N.1
-
28
-
-
0000336139
-
Regression models and life tables
-
Cox DR: Regression models and life tables. J R Stat Soc B 34:187-220, 1972
-
(1972)
J R Stat Soc B
, vol.34
, pp. 187-220
-
-
Cox, D.R.1
-
29
-
-
0003678252
-
-
Philadelphia, PA, Lippincott
-
MacDonald JS, Haller DG, Mayer RJ (eds): Manual of Oncologic Therapeutics (ed 3). Philadelphia, PA, Lippincott, 1995, pp 519-523
-
(1995)
Manual of Oncologic Therapeutics (Ed 3)
, pp. 519-523
-
-
MacDonald, J.S.1
Haller, D.G.2
Mayer, R.J.3
-
30
-
-
0027999381
-
Neurotoxicity of purine analogs: A review
-
Cheson BD, Vena DA, Foss FM, et al.: Neurotoxicity of purine analogs: A review. J Clin Oncol 12:2216-2228, 1994
-
(1994)
J Clin Oncol
, vol.12
, pp. 2216-2228
-
-
Cheson, B.D.1
Vena, D.A.2
Foss, F.M.3
-
31
-
-
0001380721
-
Immunological deficiency disorders associated with chronic lymphocytic leukemia and multiple myeloma
-
Cone L, Uhr JW: Immunological deficiency disorders associated with chronic lymphocytic leukemia and multiple myeloma. J Clin Invest 43:2241-2248, 1964
-
(1964)
J Clin Invest
, vol.43
, pp. 2241-2248
-
-
Cone, L.1
Uhr, J.W.2
-
32
-
-
0018872580
-
Richter's syndrome: Diffuse histiocytic lymphoma in patients with chronic lymphocytic leukemia. A report of five cases and review of the literature
-
Trump DL, Mann RB, Phelps R, et al.: Richter's syndrome: Diffuse histiocytic lymphoma in patients with chronic lymphocytic leukemia. A report of five cases and review of the literature. Am J Med 68:539-548, 1980
-
(1980)
Am J Med
, vol.68
, pp. 539-548
-
-
Trump, D.L.1
Mann, R.B.2
Phelps, R.3
-
33
-
-
0029118503
-
Purine nucleoside analogs: Emerging roles in indolent lymphoproliferative disorders
-
Tallman MS, Hakimian D: Purine nucleoside analogs: Emerging roles in indolent lymphoproliferative disorders. Blood 86:2463-2474, 1995
-
(1995)
Blood
, vol.86
, pp. 2463-2474
-
-
Tallman, M.S.1
Hakimian, D.2
-
34
-
-
0027323550
-
Results of fludarabine and prednisone therapy in 264 patients with chronic lymphocytic leukemia with multivariate analysis-derived prognostic model for response to treatment
-
O'Brien S, Kantarjian H, Beran M, et al.: Results of fludarabine and prednisone therapy in 264 patients with chronic lymphocytic leukemia with multivariate analysis-derived prognostic model for response to treatment. Blood 82:1695-1700, 1993
-
(1993)
Blood
, vol.82
, pp. 1695-1700
-
-
O'Brien, S.1
Kantarjian, H.2
Beran, M.3
-
35
-
-
0028931830
-
Advances in the biology and treatment of B-cell chronic lymphocytic leukemia
-
O'Brien S, del Giglio A, Keating M: Advances in the biology and treatment of B-cell chronic lymphocytic leukemia. Blood 85:307-318, 1995
-
(1995)
Blood
, vol.85
, pp. 307-318
-
-
O'Brien, S.1
Del Giglio, A.2
Keating, M.3
-
36
-
-
0028822481
-
Chronic lymphocytic leukemia
-
Rozman C, Monserrat E: Chronic lymphocytic leukemia. N Engl J Med 333:1052-1057, 1995
-
(1995)
N Engl J Med
, vol.333
, pp. 1052-1057
-
-
Rozman, C.1
Monserrat, E.2
-
37
-
-
0029099349
-
Infectious and immunosuppressive complications of purine analog therapy
-
Cheson BD: Infectious and immunosuppressive complications of purine analog therapy. J Clin Oncol 13:2431-2448, 1995
-
(1995)
J Clin Oncol
, vol.13
, pp. 2431-2448
-
-
Cheson, B.D.1
-
38
-
-
15844368449
-
Multicentre prospective randomized trial of fludarabine versus cyclophosphamide, doxorubicin, and prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia
-
Johnson S, Smith AG, Löffler H, et al.: Multicentre prospective randomized trial of fludarabine versus cyclophosphamide, doxorubicin, and prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia. Lancet 347:1432-1438, 1996
-
(1996)
Lancet
, vol.347
, pp. 1432-1438
-
-
Johnson, S.1
Smith, A.G.2
Löffler, H.3
-
39
-
-
0028228008
-
Combination of fludarabine and arabinosylcytosine for treatment of chronic lymphocytic leukemia: Clinical efficacy and modulation of arabinosylcytosine pharmacology
-
Gandhi V, Robertson LE, Keating MJ, et al.: Combination of fludarabine and arabinosylcytosine for treatment of chronic lymphocytic leukemia: Clinical efficacy and modulation of arabinosylcytosine pharmacology. Cancer Chemother Pharmacol 34:30-36, 1994
-
(1994)
Cancer Chemother Pharmacol
, vol.34
, pp. 30-36
-
-
Gandhi, V.1
Robertson, L.E.2
Keating, M.J.3
|