Decoration of lipopolysaccharide with phosphorylcholine: A phase- variable characteristic of Haemophilus influenzae

Infection and Immunity

Volumn 65, Issue 3, 1997, Pages 943-950

  Weiser, Jeffrey N ^a,b   Shchepetov, Mikhail ^a   Chong, Suzanne T H ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIACYLGLYCEROL; LIPOPOLYSACCHARIDE; PHOSPHATIDYLCHOLINE; PHOSPHORYLCHOLINE;

ANTIBODY SPECIFICITY; ARTICLE; CELL SURFACE; ENZYME ACTIVITY; EUKARYOTE; HAEMOPHILUS INFLUENZAE; LIPOGENESIS; MYCOPLASMA; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIA; TANDEM REPEAT; TRANSLATION INITIATION;

EID: 0031036365     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.3.943-950.1997     Document Type: Article

References (50)

1. Altschul, S. F., W. Gish, W. Miller, E. W. Myers, and D. J. Lipman. 1990. Basic local alignment search tool. J. Mol. Biol. 215:403-410.
2. Arondel, V., C. Benning, and C. R. Somerville. 1993. Isolation and functional expression in Escherichia coli of a gene encoding phosphatidylethanolamine methyltransferase (EC 2.1.1.17) from Rhodobacter sphaeroides. J. Biol. Chem. 268:16002-16008.
3. Brenner, S. 1987. Phosphotransferase sequence homology. Nature 329:21.
4. Briles, D. E., G. Scott, B. Gray, M. J. Crain, M. Blaese, M. Nahm, V. Scott, and P. Haber. 1987. Naturally occurring antibodies to phosphocholine as a potential index of antibody responsiveness to polysaccharides. J. Infect. Dis. 155:1307-1314.
5. Deutsch, J., M. Salman, and S. Rottem. 1995. An unusual polar lipid from the cell membrane of Mycoplasma fermentans. Eur. J. Biochem. 227:897-902.
6. Fischer, W., T. Behr, R. Hartmann, K. J. Peter, and H. Egge. 1993. Teichoic acid and lipoteichoic acid of Streptococcus pneumoniae possess identical chain structures. A reinvestigation of teichoid acid (C polysaccharide). Eur. J. Biochem. 215:851-857.
7. Fischer, W., H. U. Koch, and R. Haas. 1983. Improved preparation of lipoteichoic acids. Eur. J. Biochem. 133:523-530.
8. Fleischmann, R. D., et al. 1995. Whole-genome random sequencing and assembly of Haemophilus influenzae Rd. Science 269:497-512.
9. Flugge, U.-I., A. Weber, K. Fischer, F. Lottspiech, C. Eckerskorn, K. Waegemann, and J. Soll. 1991. The major chloroplast envelope polypeptide is the phosphate translocator and not the protein import receptor. Nature 353:364-367.
10. Gillespie, S. H., S. Ainscough, A. Dickens, and J. Lewin. 1996. Phosphorylcholine-containing antigens in bacteria from the mouth and respiratory tract. J. Med. Microbiol. 44:35-40.
11. Glaser, P., F. Kunst, M. Arnaud, M. P. Coudart, et al. 1993. Bacillus subtilis genome project: cloning and sequencing of the 97 kb region from 325 degrees to 333 degrees. Mol. Microbiol. 10:371-384.
12. Guidolin, A., J. K. Morona, R. Morona, D. Hansman, and J. C. Paton. 1994. Nucleotide sequence analysis of genes essential for capsular polysaccharide biosynthesis in Streptococcus pneumoniae type 19F. Infect. Immun. 62:5384-5396.
13. Gulig, P. A., C. C. Patrick, L. Hermanstorfer, G. H. McCracken, Jr., and E. J. Hansen. 1987. Conservation of epitopes in the oligosaccharide portion of the lipooligosaccharide of Haemophilus influenzae type b. Infect. Immun. 55:513-520.
14. Herriot, R. M., E. M. Meyer, and M. Vogt. 1970. Defined nongrowth media for stage II development of competence in Haemophilus influenzae. J. Bacteriol. 101:517-524.
15. High, N. J., M. E. Deadman, and E. R. Moxon. 1993. The role of a repetitive DNA motif (5′-CAAT-3′) in the variable expression of the Haemophilus influenzae lipopolysaccharide epitope αGal(1-4)βGal. Mol. Microbiol. 9:1275-1282.
16. Hitchcock, P. J., and T. M. Brown. 1983. Morphological heterogeneity among Salmonella lipopolysaccharide chemotypes in silver-stained polyacrylamide gels. J. Bacteriol. 154:269-277.
17. Hjelmslad, R. H., and R. M. Bell. 1990. The sn-1,2 diacylglycerol choline-phosphotransferase of Saccharomyces cerevisiae. Nucleotide sequence, transcriptional mapping, and gene product analysis of the CPT1 gene. J. Biol. Chem. 265:1755-1764.
18. Hoiseth, S. K., C. J. Connelly, and E. R. Moxon. 1985. Genetics of spontaneous, high-frequency loss of b capsule expression in Haemophilus influenzae. Infect. Immun. 49:389-395.
19. Horowitz, J., J. E. Volanakis, and D. E. Briles. 1987. Blood clearance of Streptococcus pneumoniae by C-reactive protein. J. Immunol. 138:2598-2603.
20. Inzana, T. J. 1983. Electrophoretic heterogeneity and inter strain variation of the lipopolysaccharide of Haemophilus influenzae. J. Infect. Dis. 148:492-499.
21. Johnson, K. G., and M. B. Perry. 1976. Improved techniques for the preparation of bacterial lipopolysaccharides. Can. J. Microbiol. 22:29-34.
22. Kates, M. 1986. Techniques of lipidology: isolation, analysis and identification of lipids. Elsevier Science Publishers, Amsterdam, The Netherlands.
23. Kennedy, E. 1961. Biosynthesis of complex lipids. Fed. Proc. 20:934-940.
24. Kimura, A., and E. J. Hansen. 1986. Antigenic and phenotypic variations of Haemophilus influenzae type b lipopolysaccharide and their relation to virulence. Infect. Immun. 51:69-79.
25. Kimura, A., C. C. Patrick, E. E. Miller, L. D. Cope, G. H. McCracken, Jr., and E. J. Hansen. 1987. Haemophilus influenzae type b lipopolysaccharide: stability of expression and association with virulence. Infect. Immun. 55:1979-1986.
26. Ladefoged, S. A., and G. Christiansen. 1994. Sequencing analysis reveals a unique gene organization in the gyrB region of Mycoplasma hominis. J. Bacteriol. 176:5835-5842.
27. Lamark, T., I. Kaasen, M. W. Eshoo, P. Falkenberg, J. McDougall, and A. R. Strom. 1991. DNA sequence and analysis of the bet genes encoding the osmoregulatory choline-glycine betaine pathway of Escherichia coli. Mol. Microbiol. 5:1049-1064.
28. Leon, M. A., and N. M. Young. 1971. Specificity for phosphorylcholine of six murine myeloma proteins reactive with pneumococcus C polysaccharide and beta-lipoprotein. Biochemistry 10:1424-1429.
29. Lesse, A. J., A. A. Campagnari, W. E. Bittner, and M. A. Apicella. 1990. Increased resolution of lipopolysaccharides and lipopolysaccharides utilizing tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis. J. Immunol. Methods 126:109-117.
30. Maskell, D. J., M. J. Szabo, P. D. Butler, A. E. Williams, and E. R. Moxon. 1991. Molecular analysis of a complex locus from Haemophilus influenzae involved in phase-variable lipopolysaccharide biosynthesis. Mol. Microbiol. 5:1013-1022.
31. Michalka, J., and S. Goodgal. 1969. Genetic and physical map of the chromosome of Hemophilus influenzae. J. Mol. Biol. 45:407-421.
32. Mosser, J. L., and A. Tomasz. 1970. Choline-containing teichoic acid as a structural component of pneumococcal cell wall and its role in sensitivity to lysis by an enzyme. J. Biol. Chem. 245:287-298.
33. Phillips, N., M. A. Apicella, J. M. Griffiss, and B. Gibson. 1993. Structural studies of the lipooligosaccharides from Haemophilus influenzae type b strain A2. Biochemistry 32:2003-2012.
34. Povdin, L., J. Reysset, J. Hubert, and M. Sebald. 1988. Presence of choline in teichoic acid of Clostridium acetobutylicum NI-4 and choline inhibition of autolytic function. J. Gen. Microbiol. 134:1603-1609.
35. Raetz, C. R. H. 1996. Bacterial lipopolysaccharides: a remarkable family of bioactive macroamphiphiles, p. 1035-1063. In F. C. Neidhardt, R. Curtiss III, J. L. Ingraham, E. C. C. Lin, K. B. Low, B. Magasanik, W. S. Reznikoff, M. Riley, M. Schaechter, and H. E. Umbarger (ed.), Escherichia coli and Salmonella, 2nd ed. ASM Press, Washington, D.C.
36. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
37. Schwartz, M., A. Gross, T. Steinkamp, U. I. Flugge, and R. Wagner. 1994. Ion channel properties of the reconstituted chloroplast triose phosphate/phosphate translocator. J. Biol. Chem. 269:29481-29489.
38. Schweda., E., O. Hegedus, S. Borrelli, A. Lindberg, J. Weiser, D. Maskell, and E. Moxon. 1993. Structural studies of the saccharide part of the cell envelope lipopolysaccharide from Haemophilus influenzae strain AH1-3 (lic3+). Carbohydr. Res. 246:319-330.
39. Towbin, H., T. Staehelin, and J. Gordon. 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76:4350-4354.
40. Uchida, T., and S. Yamashita. 1992. Molecular cloning, characterization, and expression in Escherichia coli of a cDNA encoding mammalian choline kinase. J. Biol. Chem. 267:10156-10162.
41. Volanakis, J. E., and M. H. Kaplan. 1971. Specificity of C-reactive protein for choline phosphate residues of pneumococcal C-polysaccharide. Proc. Soc. Exp. Biol. Med. 136:612.
42. Weiser, J. N. 1993. Relationship between colony morphology and the life cycle of Haemophilus influenzae: the contribution of lipopolysaccharide phase variation to pathogenesis. J. Infect. Dis. 168:672-680.
43. Weiser, J. N., R. Austrian, P. K. Sreenivasan, and H. R. Masure. 1994. Phase variation in pneumococcal opacity: relationship between colonial morphology and nasopharyngeal colonization. Infect. Immun. 62:2582-2589.
44. Weiser, J. N., A. A. Lindberg, E. J. Manning, E. J. Hansen, and E. R. Moxon. 1989. Identification of a chromosomal locus for expression of lipopolysaccharide epitopes in Haemophilus influenzae. Infect. Immun. 57:3045-3052.
45. Weiser, J. N., J. M. Love, and E. R. Moxon. 1989. The molecular mechanism of phase variation of H. influenzae lipopolysaccharide. Cell 59:657-665.
46. Weiser, J. N., D. J. Maskell, P. D. Butler, A. A. Lindberg, and E. R. Moxon. 1990. Characterization of repetitive sequences controlling phase variation of Haemophilus influenzae lipopolysaccharide. J. Bacteriol. 172:3304-3309.
47. Weiser, J. N., A. Williams, and E. R. Moxon. 1990. Phase-variable lipopolysaccharide structures enhance the invasive capacity of Haemophilus influenzae. Infect. Immun. 58:3455-3457.
48. Zamze, S. E., M. A. J. Ferguson, E. R. Moxon, R. A. Dwek, and T. W. Rademacher. 1987. Identification of a phosphorylated 3-deoxy-manno-octulosonic acid as a component of Haemophilus influenzae lipopolysaccharide. Biochem. J. 245:583-587.
49. Zamze, S. E., and E. R. Moxon. 1987. Composition of the lipopolysaccharide from different capsular serotype strains of Haemophilus influenzae. J. Gen. Microbiol. 133:1443-1451.
50. Zwahlen, A., L. G. Rubin, and E. R. Moxon. 1986. Contribution of lipopolysaccharide to pathogenicity of Haemophilus influenzae: comparative virulence of genetically-related strains in rats. Microb. Pathog. 1:465-473.