Role of glycoprotein PE2 in formation and maturation of the sindbis virus spike

Journal of Virology

Volumn 71, Issue 2, 1997, Pages 1558-1566

  Carleton, Michael ^a   Lee, Heuiran ^a,b   Mulvey, Matthew ^a,c   Brown, Dennis T ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN;

ARTICLE; PREDICTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN STRUCTURE; SINDBIS VIRUS; VIRUS ENVELOPE; VIRUS INFECTION; VIRUS REPLICATION;

EID: 0031035679     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.71.2.1558-1566.1997     Document Type: Article

References (54)

1. Anthony, R. P., and D. T. Brown. 1991. Protein-protein interactions in an alphavirus membrane. J. Virol. 65:1187-1194.
2. Anthony, R. P., A. M. Paredes, and D. T. Brown. 1992. Disulfide bonds are essential for the stability of the Sindbis virus envelope. Virology 190:330-336.
3. Barr, P. J. 1991. Mammalian subtilisins: the long-sought dibasic processing endoproteases. Cell 66:1-3.
4. Billstrom, M. A., and W. J. Britt. 1995. Postoligomerization folding of human cytomegalovirus glycoprotein B: identification of folding intermediates and importance of disulfide bonding. J. Virol. 69:7015-7022.
5. Bonatti, S., G. Migliaccio, G. Blobel, and P. Walter. 1984. Role of signal recognition particle in membrane assembly of Sindbis viral glycoproteins. Eur. J. Biochem. 140:499-502.
6. Bonner, W. M., and R. A. Laskey. 1974. A film detection method for tritium-labeled proteins and nucleic acids in polyacrylamide gels. Eur. J. Biochem. 46:83-88.
7. Braakman, I., H. Hoover-Litty, K. R. Wagner, and A. Helenius. 1991. Folding of influenza hemagglutinin in the endoplasmic reticulum. J. Cell Biol. 114:401-411.
8. Britt, W. J., and L. G. Vugler. 1992. Oligomerization of the human cytomegalovirus major envelope protein complex gB (gp55-116). J. Virol. 66:6747-6754.
9. Brown, D. T., and J. Edwards. 1992. Structural changes in alphaviruses accompanying the process of membrane penetration. Semin. Virol. 3:519-527.
10. Carleton, M., and D. T. Brown. 1996. Events in the endoplasmic reticulum abrogate the temperature sensitivity of Sindbis virus mutant ts23. J. Virol. 70:952-959.
11. Carleton, M., and D. T. Brown. 1996. Disulfide bridge mediated folding of Sindbis virus glycoproteins. J. Virol. 70:5541-5547.
12. Carleton, M., and D. T. Brown. Unpublished data.
13. Cheng, R. H., R. J. Kuhn, N. H. Olsen, M. G. Rossman, H. K. Choi, and T. S. Baker. 1995. Nucleocapsid and glycoprotein organization in an enveloped virus. Cell 73:823-832.
14. Collins, P. L., and G. Mottet. 1991. Homo-oligomerization of the hemagglutinin-neuraminidase glycoprotein of human parainfluenza virus type 3 occurs before the acquisition of correct intramolecular disulfide bonds and mature immunoreactivity. J. Virol. 65:2362-2371.
15. Coombs, K., and D. T. Brown. 1987. Organization of the Sindbis virus nucleocapsid as revealed by bifunctional cross-linking reagents. J. Mol. Biol. 195:359-371.
16. De Curtis, I., and K. Simons. 1988. Dissection of Semliki Forest virus glycoprotein delivery from the trans-Golgi network to the cell surface in permeabilized BHK cells. Proc. Natl. Acad. Sci USA. 85:8052-8056.
17. Doms, R. W., R. A. Lamb, J. K. Rose, and A. Helenius. 1993 Folding and assembly of viral membrane proteins. Virology 193:545-562.
18. Doms, R. W., G. Russ, and J. W. Yewdell. 1989. Brefeldin A redistributes resident and itinerant Golgi proteins to the endoplasmic reticulum. J. Cell Biol. 109:61-72.
19. Edwards, J., E. Mann, and D. T. Brown. 1983. Conformational changes in Sindbis virus envelope proteins accompanying exposure to low pH. J. Virol. 45:1090-1097.
20. Ekström, M., P. Liljeström, and H. Garoff. 1994. Membrane protein lateral interactions control Semliki Forest virus budding. EMBO J. 13:1058-1064.
21. Frolov, I., and S. Schlesinger. 1994. Comparison of the effects of Sindbis virus and Sindbis virus replicons on host cell protein synthesis and cytopatho-genicity in BHK cells. J. Virol. 68:1721-1727.
22. Garoff, H., C. Konder-Koch, R. Pettersson, and B. Burke. 1983. Expression of Semliki Forest virus proteins from cloned complementary DNA. II. The membrane-spanning glycoprotein E2 is transported to the cell surface without its normal cytoplasmic domain. J. Cell Biol. 97:652-658.
23. Gething, M. J., K. McCammon, and J. Sambrook. 1989. Protein folding and intracellular transport: evaluation of conformational changes in nascent exocytotic proteins. Methods Cell Biol. 32:185-206.
24. Hashimoto, K., S. Erdel, S. Keränen, J. Saraste, and L. Kääriäinen. 1981. Evidence for a separate signal sequence for the carboxy-terminal envelope glycoprotein E1 of Semliki Forest virus. J. Virol. 38:34-40.
25. Helenius, A. 1994. How N-linked oligosaccharides affect glycoprotein folding in the endoplasmic reticulum. Mol. Biol. Cell 5:253-265.
26. Hobman, T. C., L. Woodward, and M. G. Farquhar. 1993. The rubella virus E2 and E1 spike glycoproteins are targeted to the Golgi complex. J. Cell Biol. 121:269-281.
27. Hurtley, S. M., and A. Helenius. 1989. Protein oligomerization in the endoplasmic reticulum. Annu. Rev. Cell Biol. 5:277-307.
28. Jaenicke, R., and R. Rudolph. 1989. Folding proteins, p. 191-223. In T. E. Creighton (ed.), Protein structure: a practical approach. Oxford University Press, Oxford, United Kingdom.
29. Knipfer, M. E., and D. T. Brown. 1989. Intracellular transport and processing of Sindbis virus glycoproteins. Virology 170:117-122.
30. Konder-Koch, C., H. Riedel, K. Söderberg, and H. Garoff. 1982. Expression of the structural proteins of Semliki Forest virus from cloned cDNA microinjected into the nucleus of baby hamster kidney cells. Proc. Natl. Acad. Sci. USA 79:4525-4529.
31. Levis, R., B. G. Weiss, M. Tsiang, H. Huang, and S. Schlesinger. 1986. Deletion mapping of Sindbis virus DI RNAs derived from cDNAs defines the sequences essential for replication and packaging. Cell 44:137-145.
32. Liljeström, P., and H. Garoff. 1991. A new generation of animal cell expression vectors based on the Semliki Forest virus replicon. Bio/Technology 9:1356-1361.
33. Liljeström, P., and H. Garoff. 1991. Internally located cleavable signal sequences direct the formation of Semliki Forest virus membrane proteins from a polyprotein precursor. J. Virol. 65:147-154.
34. Liljeström, P., S. Lusa, D. Huylebroeck, and H. Garoff. 1991. In vitro mutagenesis of a full-length cDNA clone of Semliki Forest virus: the small 6,000-molecular-weight membrane protein modulates virus release. J. Virol. 65:4107-4113.
35. Liu, N., and D. T. Brown. 1993. Transient translocation of the cytoplasmic (endo) domain of a type I membrane glycoprotein into cellular membranes. J. Cell Biol. 120:877-883.
36. Liu, N., and D. T. Brown. 1993. Phosphorylation-dephosphorylation events play critical roles in Sindbis virus maturation. Virology. 196:703-711.
37. Lobigs, M., Z. Hongxing, and H. Garoff. 1990. Function of Semliki Forest virus E3 peptide in virus assembly: replacement of E3 with an artificial signal peptide abolishes spike heterodimerization and surface expression of E1. J. Virol. 64:4346-4355.
38. Melancon, P., and H. Garoff. 1986. Reinitiation of translocation in the Semliki Forest virus structural polyprotein: identification of the signal for the E1 glycoprotein. EMBO J. 5:1551-1560.
39. Migliaccio, G., M. C. Pascale, A. Leone, and S. Bonatti. 1989. Biosynthesis, membrane translocation, and surface expression of Sindbis virus E1 glycoprotein. Exp. Cell Res. 185:203-216.
40. Mulvey, M., and D. T. Brown. 1994. Formation and rearrangement of disulfide bonds during maturation of the Sindbis virus E1 glycoprotein. J. Virol. 68:805-812.
41. Mulvey, M., and D. T. Brown. 1995. Involvement of the molecular chaperone BiP in maturation of Sindbis virus envelope glycoproteins. J. Virol 69:1621-1627.
42. Mulvey, M., and D. T. Brown. 1996. Assembly of the Sindbis virus spike protein complex. Virology 219:125-132.
43. Mulvey, M., and D. T. Brown. Unpublished data.
44. Paredes, A. M., D. T. Brown, R. Rothnagel, W. Chiu, R. J. Schoepp, R. E. Johnston, and B. V. V. Prasad. 1993. Three dimensional structure of a membrane containing virus. Proc. Natl. Acad. Sci. USA 90:9095-9099.
45. Paredes, A. M., M. N. Simon, and D. T. Brown. 1992. The mass of the Sindbis virus nucleocapsid suggests it has a T=4 icosahedral symmetry. Virology 187: 329-332.
46. Presley, J. F., and D. T. Brown. 1989. The proteolytic cleavage of PE2 to envelope protein E2 is not strictly required for the maturation of Sindbis virus. J. Virol. 63:1975-1980.
47. Renz, D., and D. T. Brown. 1976. Characteristics of Sindbis virus temperature-sensitive mutants in cultured BHK-21 and Aedes albopictus (mosquito) cells. J. Virol. 19:775-781.
48. Rice, C. M., R. Levis, J. H. Strauss, and H. V. Huang. 1987. Production of infectious RNA transcripts from Sindbis virus cDNA clones: mapping of lethal mutations, rescue of a temperature-sensitive marker, and in vitro mutagenesis to generate defined mutants. J. Virol. 61:3809-3819.
49. Schlesinger, S., and M. J. Schlesinger. 1986. Formation and assembly of alphavirus glycoproteins, p. 121-148. In M. J. Schlesinger and S. Schlesinger (ed.), The Togaviridae and Flaviviridae. Plenum Publishing Corp., New York, N.Y.
50. Smith, T. J., R. H. Cheng, N. H. Olson, P. Peterson, E. Chase, R. J. Kuhn, and T. S. Baker. 1995. Putative receptor binding sites on alphaviruses as visualized by cryoelectron microscopy. Proc. Natl. Acad. Sci. USA 92:10648-10652.
51. Strauss, J. H., and E. G. Strauss. 1994. The alphaviruses: gene expression, replication, and evolution. Microbiol. Rev. 58:491-562.
52. Tatu, U., I. Braakman, and A. Helenius. 1993. Membrane glycoprotein folding, oligomerization and intracellular transport: effects of dithiothreitol in living cells. EMBO J. 12:2151-2157.
53. Watson, D. G., J. M. Moehring, and T. J. Moehring. 1991. A mutant CHO-K1 strain with resistance to Pseudomonas exotoxin A and alphaviruses fails to cleave Sindbis virus glycoprotein PE2. J. Virol. 65:2332-2339.
54. Ziemiecki, A., H. Garoff, and K. Simons. 1980. Formation of the Semliki Forest virus membrane glycoprotein complexes in the infected cell. J. Gen. Virol. 50:111-123.