Transcriptional and post-transcriptional regulation of LDL receptor gene expression in PMA-treated THP-1 cells by LDL-containing immune complexes

Journal of Lipid Research

Volumn 38, Issue 1, 1997, Pages 110-120

  Huang, Yan ^a   Ghosh, Malabika J ^a   Lopes Virella, Maria F ^a,b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b RALPH H JOHNSON VA MEDICAL CENTER   (United States)

Author keywords

cholesterol; Fc receptor; macrophage

Indexed keywords

FC RECEPTOR; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR;

ANTIGEN ANTIBODY COMPLEX; ARTICLE; CELL TRANSFORMATION; FOAM CELL; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LIPOPROTEIN METABOLISM; MACROPHAGE; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RECEPTOR BINDING; REGULATORY MECHANISM; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

ANTIGEN-ANTIBODY COMPLEX; CELL LINE; CHOLESTEROL; CHOLESTEROL ESTERS; GENE EXPRESSION REGULATION; HUMANS; LIPOPROTEINS, LDL; MONOCYTES; RECEPTORS, LDL; RNA PROCESSING, POST-TRANSCRIPTIONAL; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION, GENETIC;

EID: 0031034985     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Ross, R. 1981. A problem of the biology of the arterial wall cells and their interaction with blood components. Arteriosclerosis. 1:293-311.
2. Gisinger, C., G. T. Virella, and M. F. Lopes-Virella. 1991. Erythrocyte-bound low density lipoprotein (LDL) immune complexes lead to CE accumulation in human monocyte derived macrophages. Clin. Immunol. Immunopathol 59:37-52.
3. Lopes-Virella, M. F. and G. Virella. 1994. Atherosclerosis and autoimmunity. Clin. Immunol. Immunopathol. 73:155-167.
4. Klimov, A. N., A. D. Denisenko, A. V. Popov, V. A. Nagornev, V. M. Pleskov, A. G. Vinogradov, T. V. Denisenko, E. Y. Magracheva, G. M. Kheifes, and A. S. Kuznetzov. 1985. Lipoprotein-antibody immune complexes: Their catabolism and role in foam cell formation. Atherosclerosis. 58:1-15.
5. Klimov, A. N., A. D. Denisenko, A. G. Vinogradov, V. A. Nagornev, Y. I. Pivovarova, O. D. Sitnikova, and V. M. Pleskov. 1988. Accumulation of CE in macrophages incubated with human lipoprotein-antibody autoimmune complex. Atherosclerosis. 74:41-46.
6. Szondy, E., E. Lengyel, Z. Mezey, G. Fust, and S. Gero. 1985. Occurrence of anti-low density lipoprotein antibodies and circulating immune complexes in aged subjects. Mech. Aging Dev. 29:117-123.
7. Boullier, A., M. Hamon, E. Walters-Laporte, F. Martin-Nizart, R. Mackereel, J-C. Fruchart, M. Bertrand, and P. Duriez. 1995. Detection of autoantibodies against oxidized LDL and of IgG-bound LDL in patients with coronary heart disease. Clin. Chim. Acta. 238:1-10.
8. Bergmark, C., R. Wu, U. de Faire, A. K. Lefvert, and J. Swedenborg. 1995. Patients with early-onset peripheral vascular disease have increased levels of auto-antibodies against oxidized LDL. Arterioscler. Thromb. Vasc. Biol. 15: 441-445.
9. Ylä-Herttuala, S., W. Palinski, S. W. Butler, S. Picard, D. Steinberg and J. L. Witztum. 1994. Rabbit and human atherosclerotic lesions contain IgG that recognizes epitopes of oxidized LDL. Arterioscler. Thromb. 14:32-40.
10. Salonen, J. T., S. Ylä-Herttuala, R. Yamamoto, S. Butler, H. Korpela, R. Salonen, K. Nyyssonen, W. Palinski, and J. L. Witztum. 1992. Autoantibody against oxidized LDL and progression of carotid atherosclerosis. Lancet. 339: 883-887.
11. Maggi, E., R. Chiesa, G. Melissano, R. Castellano, D. Astore, A. Grossi, G. Finardi, and G. Bellomo. 1994. LDL oxidation in patients with severe carotid atherosclerosis: a study of in vitro and in vivo oxidation markers. Arterioscler. Thromb. 14:1892-1899.
12. Virella, G., J. F. Munoz, G. M. P. Galbraith, C. Gissinger, C. Chassereau, and M. F. Lopes-Virella. 1995. Activation of human monocyte-derived macrophages by immune complexes containing low-density lipoprotein. Clin. Immunol. Immunopathol. 75:179-189.
13. Griffith, R. L., G. T. Virella, H. C. Stevenson, and M. F. Lopes-Virella. 1988. Low density lipoprotein metabolism by human macrophages activated with low density lipoprotein immune complexes. J. Exp. Med. 168:1041-1059.
14. Aywerx, J. 1991. The human leukemia cell line. THP-1: a multifaceted model for the study of monocyte-macrophage differentiation. Experientia. 47:22-30.
15. Haberland, M. E., G. M. Fless, A. M. Scanu and A. M. Fogelman. 1992. Malondialdehyde modification of lipoprotein[a] produces avid uptake by human monocyte-rnacrophages. J. Biol. Chem. 267:4143-4151.
16. Bratzler, R. L., G. M. Chisolm, C. K. Cotton, J. A. Smith, and R. S. Lees. 1977. The distribution of labeled low density lipoproteins across the rabbit thoracic aorta in vivo. Arteriosclerosis. 28:289-309.
17. Lopes-Virella, M. F., G. K. Sherer, A. M. Lees, H. Wohltmann, R. Mayfield, J. Sagel, D. Leroy, and J. A. Colwell. 1982. Surface binding, internalization and degradation by cultured human fibroblasts of LDL isolated from type I diabetic patients: changes with metabolic control. Diabetologia. 22:430-436.
18. Lowry, O. H., N. J. Rosebrough, A. L. Farr, and R. J. Randall. 1957. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:265-275.
19. Maniatis, T., E. F. Fritsch, and J. Sambrook. 1989. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
20. Friedman, G., M. E. Wernette-Hammond, D. Y. Hui, R. W. Mahley, and T. L. Innerarity. 1987. Characterization of lipoprotein receptors on rat Fu5AH hepatoma cells. J. Lipid Res. 28:1482-1498.
21. Chen, M., J. L. Breslow, W. Li, and T. Leff. 1994. Transcriptional regulation of the apoC-III gene by insulin in diabetes mice: correlation with changes in plasma triglyceride levels. J. Lipid Res. 35:1918-1924.
22. Vitols, S., S. Norgren, G. Juliusson, L. Tatidis, and H. Luthman. 1994. Multilevel regulation of low-density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in normal and leukemic cells. Blood. 15:2689-2698.
23. Sharkey, M. F., A. Miynohara, R. L. Elam, T. Friedmann, and J. L. Witztum. 1990. Post-transcriptional regulation of retroviral vector-transduced low density lipoprotein receptor activity. J. Lipid Res. 12:2167-2178.
24. Mueckler, M. M., M. J. Merrill, and H. C. Pitol. 1983. Translational and pretranslational control of ornithine aminotransferase synthesis in rat liver. J. Biol. Chem. 258: 6109-6114.
25. Guyette, W. A., R. J. Matusik, and J. M. Rosen. 1979. Prolactin-mediated transcriptional and post-transcriptional control of casein gene expression. Cell. 17:1013-1023.
26. Wang, X., J-t,Pai, E. Wiedenfeld, J. C. Medina, C. A. Slaughter, J. L. Goldstein, and M. S. Brown. 1995. Purification of an interleukin-1b converting enzyme-related cysteine protease that cleaves sterol regulatory element-binding proteins between the leucine zipper and transmembrane domains. J. Biol. Chem. 270:18044-18050.
27. Wang, X., M. R. Griggs, X. Hua, C. Yokoyama, J. L. Goldstein, and M. S. Brown. 1993. Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. J. Biol. Chem. 268:14497-14504.