Intrapleural streptokinase versus urokinase in the treatment of complicated parapneumonic effusions: A prospective, double-blind study

American Journal of Respiratory and Critical Care Medicine

Volumn 155, Issue 1, 1997, Pages 291-295

  Bouros, Demosthenes ^a,b   Schiza, Sophia ^a   Patsourakis, George ^a   Chalkiadakis, George ^a   Panagou, Panagiotis ^a   Siafakas, Nikolaos M ^a  

^a UNIVERSITY OF CRETE   (Greece)

^b UNIVERSITY HOSPITAL OF HERAKLION   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

STREPTOKINASE; UROKINASE;

ADOLESCENT; ADULT; AGED; ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; ECHOGRAPHY; FEMALE; FIBRINOLYTIC THERAPY; HOSPITALIZATION; HUMAN; INFLAMMATION; INTRAPLEURAL DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; PLEURA EFFUSION; PLEURA EMPYEMA; PNEUMONIA; PRIORITY JOURNAL; THORAX RADIOGRAPHY; TUBE;

EID: 0031034568     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.155.1.9001327     Document Type: Article

References (35)

1. Light, R. W., W. M. Girard, S. G. Jenkinson, and R. B. Goerge. 1980. Parapneumonic effusions. Am. J. Med. 69:507-512.
2. Sahn, S. A., and R. W. Light. 1989. The sun should never set on a parapneumonic effusion. Chest 95:945-946.
3. Taryle, D. A., D. E. Potts, and S. A. Sahn. 1978. The incidence and clinical correlates of parapneumonic effusions in pneumococcal pneumonia. Chest 74:170-173.
4. Sahn, S. A. 1993. Management of complicated parapneumonic effusions. Am. Rev. Respir. Dis. 148:813-817.
5. Andrews, N. C., E. F. Parker, R. R. Shaw, N. J. Wilson, and W. R. Webb. 1962. Management of nontuberculous empyema: a statement of the subcommittee on surgery. Am. Rev. Respir. Dis. 85:935-936.
6. Light, R. W. 1985. Parapneumonic effusions and empyema. Clin. Chest Med. 6:55-62.
7. Bartlett, J. G. 1988. Bacterial infections of the pleural space. Semin. Respir. Infect. 3:308-321.
8. Orringer, M. B. 1988. Thoracic empyema: back to basics. Chest 93: 901-902.
9. Heffner, J. E., L. K. Brown, C. Barbieri, and J. M. DeLeo. 1995. Pleural fluid chemical analysis in parapneumonic effusions: a meta-analysis. Am. J. Respir. Crit. Care Med. 151:1700-1708.
10. Bouros, D., S. Schiza, P. Panagou, J. Drositis, and N. M. Siafakas. 1994. Role of SK in the treatment of acute loculated parapneumonic pleural effusions and empyema. Thorax 49:852-855.
11. Kaplan, D. K. 1994. Treatment of empyema thoracis. Thorax 49:845-846.
12. Strange, C., and S. A. Sahn. 1991. Management of parapneumonic pleural effusions and empyema. Infect. Dis. Clin. North Am. 5: 539-559.
13. Tillet, W. S., and S. Sherry. 1949. The effect in patients of streptococcal fibrinolysis (streptokinase) and streptococcal desoxyribonuclease on fibrinous purulent, and sanguinous pleural exudations. J. Clin. Invest. 28:173-190.
14. Bergh, N. P., R. Ekroth, S. Larsson, and P. Nagy. 1977. Intrapleural streptokinase in the treatment of hemothorax and empyema. Scand. J. Thorac. Cardiovasc. Surg. 11:265-268.
15. Fraedrich, G., D. Hoffmann, P. Effenhauser, and R. Jander. 1982. Instillation of fibrinolytic enzymes in the treatment of pleural empyema. Thorac. Cardiovasc. Surg. 30:36-38.
16. Mitchell, M. E., W. M. Alberts, K. W. Chandler, and A. L. Goldman. 1989. Intrapleural streptokinase in management of parapneumonic effusions: report of series and review of literature. J. Fla. Med. Assoc. 76:1019-1022.
17. Willsie-Ediger, S. K., G. Salzman, G. Reisz, and M. G. Foreman. 1990. Use of intrapleural streptokinase in the treatment of thoracic empyema. Am. J. Med. Sci. 30:296-300.
18. Aye, R. W., D. P. Froese, and L. D. Hill. 1991. Use of purified streptokinase in empyema and hemothorax. Am. J. Surg. 161:560-562.
19. Henke, C. A., and J. W. Leatherman. 1992. Intrapleurally administered streptokinase in the treatment of acute loculated non purulent parapneumonic effusions. Am. Rev. Respir. Dis. 145:680-684.
20. Aflageme, I., F. Munoz, N. Pena, and S. Umbrias. 1993. Empyema of the thorax in adults: etiology, biologic findings, and management. Chest 103:839-843.
21. Taylor, R. F. H., M. B. Rubens, M. C. Pearson, and N. C. Barnes. 1994. Intrapleural SK in the management of empyema. 49:856-859.
22. Moulton, J. S., P. T. Moore, and R. A. Mencini. 1989. Treatment of loculated pleural effusions with transcatheter intracavitary UK. A.J.R. 153:941-945.
23. Lee, K. S., J. G. Im, Y. H. Kim, S. H. Hwang, W. K. Bae, and B. H. Lee. 1991. Treatment of thoracic multiloculated empyemas with intracavitary UK: a prospective study. Radiology 179:771-775.
24. Robinson, L. A., A. Moulton, W. H. Flemming, A. Alonso, and T. A. Galbraith. 1994. Intrapleural fibrinolytic treatment of multiloculated thoracic empyemas. Ann. Thorac. Surg. 57:803-814.
25. Pollack, J. S., and C. S. Passik. 1994. Intrapleural UK in the treatment of loculated pleural effusions. Chest 105:868-873.
26. Couser, J. I., J. Berley, and E. G. Timm. 1992. Intrapleural urokinase for loculated effusions. 101:1467-1469.
27. Bouros, D., A. Schiza, N. Tzanakis, J. Drositis, and N. M. Siafakas. 1996. Urokinase in the treatment of complicated parapneumonic effusions and empyema. Eur. Respir. J. 9:1656-1659.
28. Hippocrates. 1984. Aphorisms, V. Loeb Classical Library, Harvard University Press, Cambridge, MA.
29. Light, R. W. 1995. A new classification of parapneumonic effusions and empyema. Chest 108:299-301.
30. Berger, H. A., and M. L. Morganroth. 1990. Immediate drainage is not required for all patients with complicated parapneumonic effusions. Chest 97:731-735.
31. Holden, R. W. 1990. Plasminogen activators: pharmacology and therapy. Radiology 174:993-1001.
32. Lahora, J. M., J. R. Haaga, T. Stellato, T. Flanigan, and R. Graham. 1993. Safety of intracavitary urokinase with percutaneous abscess drainage. A.J.R. 160:171-174.
33. Schiza, S., D. Bouros, P. Panagou, J. Drositis, N. Tzanakis, and N. Siafakas. 1994. Intrapleural SK vs. UK in the treatment of loculated parapneumonic effusions. Eur. Respir. J. 7:272s.
34. Vidovich, R. R., D. E. Heiselman, and D. Hudok. 1992. Treatment of urokinase-related anaphylactoid reaction with intravenous famotidine. Ann. Pharmacother. 26:782-783.
35. Ward, G. L. H., D. E. Heiseiman, and L. J. White. 1992. Pulsus paradoxus in anaphylactic shock due to urokinase administration. Chest 101:589.