Protection by diphenyliodonium against glutamate neurotoxicity due to blocking of N-methyl-D-aspartate receptors

Neuroscience

Volumn 76, Issue 2, 1997, Pages 459-466

  Nakamura, Y ^a   Tsuji, K ^a   Shuto, M ^b   Ogita, K ^b   Yoneda, Y ^b   Shimamoto, K ^c   Shibata, T ^a   Kataoka, K ^a  

^a EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SETSUNAN UNIVERSITY   (Japan)

^c SUNTORY INSTITUTE FOR BIOORGANIC RESEARCH   (Japan)

Author keywords

Ca2+ influx; Ca2+ microfluorometry; Diphenyleneiodonium; Dizocilpine maleate (MK 801); NMDA receptor antagonist; NOS inhibitor

Indexed keywords

DIPHENYLIODONIUM SALT; DIZOCILPINE; FURA 2; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROPROTECTIVE AGENT;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL CULTURE; CONTROLLED STUDY; EMBRYO; INTRACELLULAR RECORDING; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BIPHENYL COMPOUNDS; CALCIUM; CELLS, CULTURED; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; GLUTAMIC ACID; N-METHYLASPARTATE; NEURONS; NITRIC OXIDE SYNTHASE; ONIUM COMPOUNDS; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 0031034291     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(96)00375-2     Document Type: Article

References (34)

1. Benveniste H., Drejer J., Schousboe A. and Diemer N. H. (1984) Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J. Neurochem. 43, 1369-1374.
2. Bradford M. M. (1976) A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Analyt. Biochem. 72, 248-254.
3. Choi D. W. (1988) Glutamate neurotoxicity and diseases of the nervous system. Neuron 1, 623-634.
4. Choi D. W., Maulucci-Gedde M. and Kriegstein A. R. (1987) Glutamate neurotoxicity in cortical cell culture. J. Neurosci. 7, 357-368.
5. Choi D. W. and Rothman S. M. (1990) The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. A. Rev. Neurosci. 13, 171-182.
6. Cross A. R. and Jones O. T. G. (1986) The effect of the inhibitor diphenyleneiodonium on the superoxide generating system of neutrophils: specific labeling of a component polypeptide of the oxidase. Biochem. J. 237, 111-116.
7. Dawson V. L., Dawson T. M., Bartley D. A., Uhi G. R. and Snyder S. H. (1993) Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures. J. Neurosci. 13, 2651-2661.
8. Finkbeiner S. and Stevens C. F. (1988) Applications of quantitative measurements for assessing glutamate neurotoxicity. Proc. natn. Acad. Sci. U.S.A. 85, 4071-4074.
9. Frandsen A. and Schousboe A. (1987) Time and concentration dependency of the toxicity of excitatory amino acids on the cerebral neurons in primary culture. Neurochem. Int. 10, 583-591.
10. Frandsen A. and Schousboe A. (1990) Development of excitatory amino acid induced cytotoxicity in cultured neurons. Int. J. devl Neurosci. 8, 209-216.
11. Hancock J. T. and Jones O. T. G. (1987) The inhibition by diphenyleneiodonium and its analogues of superoxide generation by macrophages. Biochem. J. 242, 103-107.
12. Hewett S. J., Corbett J. A., McDaniel M. L. and Choi D. W. (1993) Inhibition of nitric oxide formation does not protect murine cortical cell cultures from N-methyl-D-aspartate neurotoxicity. Brain Res. 625, 337-341.
13. Hewett S. J., Csernansky C. A. and Choi D. W. (1994) Selective potentiation of NMDA-induced neuronal injury following induction of astrocytic iNOS. Neuron 13, 487-494.
14. Holland P. C., Clark M. G., Bloxham D. P. and Lardy H. A. (1973) Mechanism of action of the hypoglycemic agent diphenyleneiodonium. J. biol. Chem. 248, 6050-6056.
15. Koh J. Y. and Choi D. W. (1987) Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay. J. Neurosci. Meth. 20, 83-90.
16. Lernner-Natoli M., Rondouin G., Debock F. and Bockaert J. (1992) Chronic NO synthase inhibition fails to protect hippocampal neurons against NMDA toxicity. NeuroReport 3, 1109-1112.
17. Mitani A., Kubo H., Iga K., Imon H., Kadoya F. and Kataoka K. (1990) A new enzymatic cycling technique for glutamate determination in brain microdialysates. J. Neurochem. 54, 709-711.
18. Morioka T., Kalehua A. N. and Streit W. J. (1991) The microglial reaction in the rat dorsal hippocampus following transient forebrain ischemia. J. cerebr. Blood Flow Metab. 11, 966-973.
19. Ogata T., Nakamura Y., Tsuji K., Shibata T. and Kataoka K. (1993) Steroid hormones protect spinal cord neurons from glutamate toxicity. Neuroscience 55, 445-449.
20. 2+ mobilization in conjunction with metabotropic glutamate receptor activation by t-ACPD in cultured hippocampal astrocytes. Neurosci. Lett. 170, 5-8.
21. Ogita K., Ohkawara A., Suzuki T., Ohgaki T., Uchida S., Meguri H. and Yoneda Y. (1992) Effects of ifenprodil on the N-methyl-D-aspartate receptor ionophore complex in rat brain. Neurochem. Int. 21, 135-147.
22. Olney J. W. (1969) Brain lesions, obesity and other disturbances in mice treated with monosodium glutamate. Science 164, 719-721.
23. Olney J. W., Ho O. L. and Rhee V. (1971) Cytotoxic effects of acidic and sulfur-containing amino acids on the infant mouse central nervous system. Expl Brain Res. 14, 61-76.
24. Pauwels P. J. and Leysen J. E. (1992) Blockade of nitric oxide formation does not prevent glutamate-induced neurotoxicity in neuronal cultures from rat hippocampus. Neurosci. Lett. 143, 27-30.
25. Regan R. F. and Choi D. W. (1991) Glutamate neurotoxicity in spinal cord cell culture. Neuroscience 43, 585-591.
26. Regan R., Renn K. and Pnter S. S. (1993) NMA neurotoxicity in murine cortical cell cultures is not attenuated by hemoglobin or inhibition of nitric oxide synthesis. Neurosci. Lett. 153, 53-56.
27. Rothman S. M. and Olney J. W. (1987) Excitoxicity and NMDA receptor. Trends Neurosci. 10, 299-302.
28. Rothman S. M., Thurston J. H. and Hauhart R. E. (1987) Delayed neurotoxicity of excitatory amino acids in vitro. Neuroscience 22, 471-480.
29. Schumidt-Kastner R., Szymas J. and Hossmann K.-A. (1990) Immunohistochemical study of glial reaction and serum-protein extravasation in relation to neuronal damage in rat hippocampus after ischemia. Neuroscience 38, 527-540.
30. Stuehr D. J., Fasehun O. A., Kwon N. S., Gross S. S., Gonzalez J. A., Levi R. and Nathan C. F. (1991) Inhibition of macrophage and endothelial cell nitric oxide synthase by diphenyleneiodonium and its analogs. Fedn Proc. Fedn Am. Socs exp. Biol. 5, 98-103.
31. Tsuji K., Nakamura Y., Ogata T., Mitani A., Kataoka K., Shibata T., Ishida M. and Shinozaki H. (1995) Neurotoxicity of acromelic acid in cultured neurons from rat spinal neurons. Neuroscience 68, 585-591.
32. Tsuji K., Nakamura Y., Ogata T., Shibata T. and Kataoka K. (1994) Rapid decrease in ATP content without recovery phase during glutamate-induced cell death in cultured spinal neurons. Brain Res. 662, 289-292.
33. Wong E. H. F., Kemp J. A., Priestley T., Knight A. R., Woodruff G. N. and Iversen L. L. (1986) The anticonvulsant MK801 is a potent N-methyl-D-aspartate antagonist. Proc. natn. Acad. Sci. U.S.A. 83, 7104-7108.
34. Yoneda Y., Enomoto R. and Ogita K. (1994) Supporting evidence for negative modulation by protons of an ion channel associated with the N-methyl-D-aspartate receptor complex in rat brain using ligand binding techniques. Brain Res. 636, 298-307.