Treatment of chronic postoperative otorrhea with cultured keratinocyte sheets

Annals of Otology, Rhinology and Laryngology

Volumn 106, Issue 1, 1997, Pages 15-21

  Verbeken, Gilbert ^b   Duinslaeger, Luc ^b   Somers, Thomas ^a   Vanhalle, Stefaan ^b   Govaerts, Paul ^a   Delaey, Bernard ^b   Offecirs, Erwin ^a  

^a SINT AUGUSTINUS HOSPITAL   (Belgium)

^b QUEEN ASTRID MILITARY HOSPITAL   (Belgium)

Author keywords

cytokine; growth factor; keratinocyte; middle ear surgery; otorrhea; tympanoplasty

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; ATRESIA; CELL MIGRATION; CHOLESTEATOMA; CLINICAL ARTICLE; CLINICAL TRIAL; EPITHELIZATION; HUMAN; HUMAN CELL; HUMAN TISSUE; KERATINOCYTE; OTITIS MEDIA; OTORRHEA; PRIORITY JOURNAL; SCHOOL CHILD; WOUND HEALING;

EID: 0031034068     PISSN: 00034894     EISSN: None     Source Type: Journal    
DOI: 10.1177/000348949710600103     Document Type: Article

References (26)

1. Youngs R. The histopathology of mastoidectomy cavities, with particular reference to persistent disease leading to chronic otorrhoea. Clin Otolaryngol 1992;17:505-10.
2. Marquet J, Declau F. Congenital middle ear malformations. Acta Otorhinolaryngol Belg 1988;42:122-302.
3. Hamans EPPM, Govaerts PJ, Somers T, Offeciers FE. Allograft tympanoplasty type 1 in the childhood population, Ann Otol Rhinol Laryngol 1996;105:871-6.
4. Duinslaeger L, Verbeken G, Delaey B, Vanhalle S, Vanderkelen A. Lyophilized keratinocyte cell lysates contain multiple mitogenic activities and stimulate closure of meshed skin autograft-covered burn wounds with similar efficiency as fresh allogenic keratinocyte cultures. Plast Reconstr Surg (in press).
5. Madden MR, Finkelstein JL, Staiano-Coico L, et al. Grafting of cultured allogeneic epidermis on second- and third-degree burn wounds on 26 patients. J Trauma 1986;26:955-62.
6. Marcusson J, Lindgren C, Berghard A, Toftgård R. Allogeneic cultured keratinocytes in the treatment of leg ulcers: a pilot study. Acta Derm Venereol (Stockh) 1992;72:61-4.
7. Blight A, Fatah MF, Datubo-Brown DD, Mountford EM, Cheshire IM. The treatment of donor sites with cultured epithelial grafts. Br J Plast Surg 1991;44:12-4.
8. De Luca M, Albanese E, Bondanza S, et al. Multicentre experience in the treatment of bums with autologous and allo geneic cultured epithelium, fresh or preserved in a frozen state. Burns 1989;15:303-9.
9. McAree KG, Klein RL, Boeckman CR. The use of cultured epithelial autografts in the wound care of severely burned patients. J Pediatr Surg 1993;28:166-8.
10. Lee AJ, Jackler RK, Kato BM, Scott NM. Repair of chronic tympanic membrane perforations using epidermal growth factor progress toward clinical application. Am J Otol 1994;15:10-8.
11. Rheinwald JG, Green H. Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells. Cell 1975;6:331-44.
12. Alberti PWRM. Epithelial migration on the tympanic membrane. J Laryngol Otol 1964;78:808-30.
13. Litton WB. Epidermal migration in the ear: the location and characteristics of the generation center revealed by utilizing a radioactive desoxyribose nucleic acid precursor. Acta Otolaryngol [Suppl] (Stockh) 1968(suppl 240).
14. Boedts D, Kuijpers W. Epithelial migration on the tympanic membrane. Acta Otolaryngol (Stockh) 1978;85:248-52.
15. Somers T, De Cubber J, Daemers K, Govaerts P, Offeciers FE. The bone anchored hearing aid and auricular prosthesis. Acta Otorhinolaryngol Belg 1994;48:343-9.
16. Reijnen CJH, Kuijpers W. The healing pattern of the drum membrane. Acta Otolaryngol [Suppl] (Stockh) 1971(suppl 287).
17. Premachandra DJ, Woodward B, Milton CM, Sergeant RJ, Fabre JW. Long-term results of mastoid cavities grafted with cultured epithelium prepared from autologous epidermal cells to prevent chronic otorrhea. Laryngoscope 1993;103:1121-5.
18. Proops DW, Hawke WM, Parkinson EK. Tissue culture of migratory skin of the external ear and cholesteatoma: a new research tool. J Otolaryngol 1984;13:63-9.
19. Phillips TJ. Biologic skin substitutes. J Dermatol Surg Oncol 1993;19:794-800.
20. Eisinger M, Sadan S, Silver IA, Flick RB. Growth regulation of skin cells by epidermal cell-derived factors: implications for wound healing. Proc Natl Acad Sci USA 1988;85:1937-41.
21. Burt AM, Pallett CD, Sloane JP, et al. Survival of cultured allografts in patients with burns assessed with probe specific for Y chromosome. BMJ 1989;298:915-9.
22. Morhenn VB, Benike CJ, Cox AJ. Cultured human epidermal cells do not synthesize HLA-DR. J Invest Dermatol 1982;78:32-7.
23. Mondain M, Ryan A. Histological study of the healing of traumatic tympanic membrane perforation after basic fibroblast growth factor application. Laryngoscope 1993;103:312-8.
24. Kirsner RS, Falanga V, Eaglstein WH. The biology of skin grafts. Arch Dermatol 1993;129:481-3.
25. Falanga V. Growth factors and wound healing. Dermatol Clin 1993;11:667-75.
26. Govaerts PJ, Jacob WA, Marquet J. Histological study of thin replacement membrane of human tympanic membrane perforations. Acta Otolaryngol (Stockh) 1988;105:297-302.