The tumour associated cell surface antigen A6H is costimulatory for human CD4+ but not CD8+ cells

Immunology

Volumn 90, Issue 2, 1997, Pages 236-243

  Labuda, T ^a   Parra, E ^a   Hedlund, G ^a,b   Kalland, T ^a   Dohlsten, M ^a,b  

^a LUND UNIVERSITY   (Sweden)

^b Pharmacia & Upjohn AB   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; MONOCLONAL ANTIBODY; TRANSCRIPTION FACTOR; TUMOR ANTIGEN;

ADULT; ARTICLE; GENETIC REGULATION; HUMAN; HUMAN CELL; IMMUNOREGULATION; KIDNEY CARCINOMA; LYMPHOCYTE ACTIVATION; NORMAL HUMAN; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

EID: 0031033962     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1997.00149.x     Document Type: Article

References (37)

1. MUELLER D. L., JENKINS M. K & SCHWARTZ R. (1989) Clonal expansion vs. clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy. Ann Rev Immunol 7, 445.
2. JENKINS M. K. & JOHNSON J. G. (1993) Molecules involved in T cell costimulation. Curr Opin Immunol 5, 361.
3. JANEWAY C. A. JR. & GOLDSTEIN P. (1993) Lymphocyte activation and effector functions, editorial overview: the role of cell surface molecules. Curr Opin Immunol 5, 313.
4. ROBEY E. & ALLISON J.P. (1995) T cell activation: integration of signals from the antigen receptor and costimulatory molecules. Immunol Today 16, 307.
5. BOUSSIOTIS V. A., GRIBBEN J. G., FREEMAN G. J. & NADLER L. M. (1994) Blockade of the CD28 co-stimulatory pathway: a means to induce tolerance. Curr Opin Immunol 6, 797.
6. JENKINS M. & SCHWARTZ R. (1987) Antigen presentation by chemically modified splenocytes induces antigen specific T cell unresponsiveness in vitro and in vivo. J Exp Med 165, 302.
7. SPRINGER T. A. (1990) Adhesion receptors of the immune system. Nature 346, 425.
8. VAN SEVENTER G. A., NEWMWN W., SHIMIZU Y. et al. . (1991) Analysis of T cell stimulation by superantigen plus major histocompatibility complex class 11 molecules or by CD3 monoclonal antibody: costimulation by purified adhesion ligands VCAM-1, ICAM-1 but not ELAM-I. Exp Med 174, 901.
9. FISHER H., GJÖRLOFF A., HEDLUND G. et al. (1992) Stimulation of human naive and memory T helper cells with bacterial super antigen. Naive CD4 + 45RA + T cells require a costimulatory signal mediated through the LFA-1/ICAM-1 pathway. J Immunol 148 (1993)
10. CLARK E. A. & LEDBETTER J. A. (1994) How B and Tcells talk to each other. Nature 367, 425.
11. SHIMIZU Y., VAN SEVENTER G. A., HORGAN K. J. & SHAW S. (1990) Roles of adhesion molecules in T cell recognition: Fundamental similarities between four integrins on resting human T cells (LFA-1, VLA-4, VLA-5, VLA-6 in expression, binding and costimulation. Immunological Rev 114, 109.
12. LABUDA T., LANDO P., BJÖRKDAHL O. et al. (1995) A novel co-stimulatory T cell antigen co-expressed on renal cell carcinoma. Int Immunol 7, 1425.
13. VESSELLA R. L., MOON T.D., CHIOU R. K. et al. (1985) Monoclonal antibodies to human renal cell carcinoma: recognition of shared and restricted tissue antigens. Cancer Research 45, 6131.
14. JAIN J., LOH C. & RAO A. (1995) Transcriptional regulation of the IL-2 gene. Curr Opin Immunol 7, 333.
15. NABEL G. & BALTIMORE D. (1987) An inducible transcription factor activates expression of human immunodeficiency virus in T cells. Nature 326, 711.
16. GHOSH P., TAN T. H., RICE N. R., SICA A. & YOUNG H. A. (1992) The interleukin 2 CD28 responsive complex contains at least three members of the NF-κB family: c-rel, p50 and p65. Proc Natl Acad Sci USA 90, 1696.
17. ULLMAN K. S., NORTHROP J. P., ADMON A. & CRABTREE G. R. (1992) Jun family members are controlled by a calcium-regulated, cyclosporin A-sensitive signalling pathway in activated T lymphocytes. Genes Dev 7, 188.
18. DOHLSTEN M., HEDLUND G., ÅKERBLOM E., LANDO P. A. & KALLAND T. (1991) Monoclonal antibody-targeted superantigens: a different class of anti-tumor agents. Proc Natl Acad Sci USA 88, 9287.
19. LINSLEY P. S., BRADY W., URNES M., GROSMAIRE L. S. DAMLE N. K. & LEDBETTER J. (1991) CTLA-4 is a second ligand for B cell activation antigen B7. J exp Med 174, 561.
20. ABRAHAMSÉN L., DOHLSTEN M., SEGREN S., BJÖRK P., JONSSON E. & KALLAND T. (1995) Characterization of two distinct MHC class II binding sites in the superantigen staphyloccocal enterotoxin A. EMBO J 14, 2978.
21. WINGREN A. G., HEDLUND G., KALLAND T. et al. (1992) The LFA-3 adhesion pathway is differently utilized by superantigenactivated human CD4 + T-cell subsets. Scand J Immunol 36, 243.
22. CARLSSON R., FISCHER H. & SJÖGREN H. O. (1988) Binding of staphylococcal enterotoxin to accessory cells is a requirement for its ability to activate human T cells. J Immunol 140, 2484.
23. LANDO P. A., DOHLSTEN M., HEDLUND G., BRODIN T., SANSOM D. & KALLAND T. (1993) Co-stimulation with B7 and targeted superantigen is required for MHC class II-independent T-cell proliferation but not cytotoxicity. Immunology 80, 236.
24. PARRA E., VARGA M., SIGVARDSSON M. et al. (1995) Costimulation of human CD4 + T cells with LFA-3 and B7 induce distinct effects on AP-1 and NF-κB transcription factors. J Immunol 155, 1132.
25. MANIATIS T., FRITSCH E. F & SAMBROOK S. (1982) In: Molecular cloning: A Laboratory Manual. p. 91. Cold Spring Harbor Laboratories, Cold Spring Harbor, NY.
26. ROMANO F. M., BISOGNI R., LAMBERTI A. et al. (1994) Regulation of NF-κB nuclear activity in peripheral blood mononuclear cells: role of CD28 antigen. Cell Immunol 156, 371.
27. RINCON M. & FLAVELL R. A. (1994) AP-1 transcriptional activity requires both T cell receptor-mediated and co-stimulatory signals in primary T lymphocytes. EMBO J 13, 43726.
28. CROFT M. (1994) Activation of naive, memory and effector T cells. Curr Opin Immunol 6, 431.
29. JUNE C. H., LEDBETTER J. A., LINDSTEN T. & THOMSON C.B. (1989) Evidence for the involvement of three distinct signals in the induction of IL-2 gene expression in human T lymphocytes. J Immunol 143, 153.
30. WINGREN A. G., PARRA E., VARGA M. et al. (1995) T cell activation pathways: B7, LFA-3 and ICAM-1 shape unique T cell profiles. Crit Rev Immunol 15, 235.
31. DURAND D. B., SHAW J. P, BUSH M. R., REPLOGE R. E., BELAGAJE R. & CRABTREE G.R. (1988) Characterization of antigen receptor response elements within the IL-2 enhancer Mol Cell Biol 8, 1715.
32. ULLMAN K. S., NORTHROP J. P., VERWEIJ C.L. & CRABTREE G. (1990) Transmission of signals from the T lymphocyte surface receptor to the genes responsible for cell proliferation and immune function: the missing link. Annu Rev Immunol 8, 421.
33. PIPERNO A. G. & NOLAN P. (1991) Nuclear transcription factors that bind to elements of the IL-2 promoter: induction requirements in primary human T cells. J Immunol 147, 2734.
34. JAIN J., VALGE-ARCHER V. E. & RAO A. (1992) Analysis of the AP-1 sites in the IL-2 promoter. J Immunol 148, 1240.
35. RYSECK R. P. & BRAVO R. (1991) C-Jun, Jun-B and Jun-D differ in their binding affinities to AP-1 and CRE consensus sequences: effect of Fos proteins. Oncogene 6, 533.
36. LOS M., SCHENK H., BAUERLE P. A. DRÖGE W. & OSTHOFF K. S. (1995) IL-2 gene expression and NF-κB activation through CD28 requires reactive oxygen production by 5-lipoxygenase. EMBO J 14, 3731.
37. BING S., JACINTO E., HIBI M., KALLUNKI T., KARIN M. & BEN-NERIAH Y. (1994) JNK is involved in signal integration during costimulation of T lymphocytes. Cell. 77, 727.