Efficient and β-stereoselective synthesis of 4(5)-methyl-5(4)-(5- amino-5-deoxy-β-D-ribofuranosyl)imidazole and related compounds exhibiting antiulcer activity

Chemical and Pharmaceutical Bulletin

Volumn 45, Issue 1, 1997, Pages 53-61

  Harusawa, Shinya ^a   Moriyama, Hideki ^a   Murai, Yoshihiko ^a   Imazu, Tomonari ^a   Ohishi, Hirofumi ^a   Yoneda, Ryuji ^a   Kurihara, Takushi ^a   Hata, Hiroyoshi ^b   Sakamoto, Yasuhiko ^b  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b Nippon Shoji Kaisha Ltd   (Japan)

Author keywords

antiulcer activity; imidazole C nucleoside; Mitsunobu reaction; X ray analysis

Indexed keywords

1 CYANO 2 METHYL 3 [5 DEOXY 1 (1H IMIDAZOL 4(5) YL) BETA D RIBOFURANOS 5 YL]GUANIDINE; 4(5) [5 DEOXY 5 (N PHENYLTHIOUREIDO) BETA D RIBOFURANOSYL]IMIDAZOLE; ANTIULCER AGENT; HISTAMINE H2 RECEPTOR ANTAGONIST; IMIDAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONOTROPISM; CONTROLLED STUDY; DRUG EFFICACY; DRUG SYNTHESIS; GUINEA PIG; HEART ATRIUM; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; STEREOCHEMISTRY; STOMACH ULCER;

EID: 0031033747     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.45.53     Document Type: Article

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