Modulation of human hepatocyte acute phase protein production in vitro by n-3 and n-6 polyunsaturated fatty acids

Annals of Surgery

Volumn 225, Issue 1, 1997, Pages 103-111

  Wigmore, Stephen J ^a   Fearon, Kenneth C H ^a   Ross, James A ^a  

^a ROYAL INFIRMARY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE PHASE PROTEIN; ALPHA 1 ANTICHYMOTRYPSIN; BOVINE SERUM ALBUMIN; C REACTIVE PROTEIN; GAMMA LINOLENIC ACID; HAPTOGLOBIN; ICOSAPENTAENOIC ACID; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PREALBUMIN; RECOMBINANT INTERLEUKIN 6; TRANSFERRIN;

ACUTE PHASE RESPONSE; ARTICLE; CELL COUNT; CELL FUNCTION; CELL ISOLATION; CELL STIMULATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; LIVER CELL; LIVER CELL CULTURE; METABOLIC REGULATION; PRIORITY JOURNAL; PROTEIN METABOLISM;

ACUTE-PHASE PROTEINS; CELLS, CULTURED; FATTY ACIDS, UNSATURATED; HUMANS; INTERLEUKIN-6; LIVER;

EID: 0031033707     PISSN: 00034932     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000658-199701000-00012     Document Type: Article

References (36)

1. Endres S, Ghorbani R. Kelley VE, et al. The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of imerleukin-1 and tumour necrosis factor by mononuclear cells. N Engl J Med 1989; 320:265-271.
2. Falconer JS, Ross JA, Fearon KCH, et al. Effect of eicosapentaenoic acid and other fatty acids on the growth in vitro of human pancreatic cancer cell lines, Br J Cancer 1994; 69:826-832.
3. Beck SA, Smith KL, Tisdate MJ. Amicachectic and antitumor effect of eicosapentaenoic acid and its effect on protein turnover. Cancer Res 1991; 51:6089-6093.
4. Tisdale MJ, Beck SA, Inhibition of tumour-induced lipolysis in vitro and caehexia and tumour growth In vivo by eicosapentaenoic acid. Biochem Pharmacol 1991; 41:103-107.
5. Tisdale MJ, Dhesi JK. Inhibition of weight loss by ∂-3 fatty acids in an experimental cachexia model. Cancer Res 1990: 50:5022-5026.
6. Begin ME, Ells G, Horrobin DF. Polyunsaturated fatty acid-induced cytotoxicity against tumour cells and its relationship to lipid peroxidation. J Natl Cancer Inst 1988; 80:188-194.
7. Wigmore SJ, Falconer JS, Fearon KCH. Fatty acids for treating pancreatic cancer. Br Med J 1994; 309:544.
8. Hwang D. Essential fatty acids and the immune response. FASEB J 1989; 3:2052-2061.
9. Fisher M, Levine PH. Weiner BH, et al. Metabolism of eicosapentaenoic acid by aorta: formation of a novel 13-hydroxylated prostagiandin, Biochim Biophys Acta 1985; 835:201-211.
10. Virella G. Kilpatrick JM, Rugeles MT, et al. Depression of humoral responses and phagocytic functions in vivo and in vitro by fish oil and eicosapentaenoic acid. Clin Immunol Immunopathol 1989; 52:257-270.
11. Cooper AL, Gibbons L, Koran MA, et al. Effect of dietary fish oil supplementation on fever and cytoktne production in human volunteers. Clin Nutr 1993; 12:321-328.
12. Pomposelli JJ, Mascioli EA, Bistrian BR, et al. Attenuation of the febrile response in guinea pigs by fish oil enriched diets, JPEN J Parenter Enteral Nutr 1989; 13:136-140.
13. Heinrich PC, Castell JV, Andus T. Interleukin-6 and the acute phase response, Biochem J 1990; 265:621-636.
14. Selby P, Hobbs S, Viner C, et al. Tumour necrosis factor in man: Clinical and biological observations. Br J Cancer 1987; 56:803-808.
15. Starnes HF, Warren RS. Jeevanandam M. et al. Tumour necrosis factor and the acute metabolic response to tissue injury in man. J Clin Invest 1988; 82:1321-1325.
16. Falconer JS, Fearon KCH, Plester CE. et al, Cytokines, the acute phase response and pancreatic cancer. Ann Surg 1994; 219:325-331.
17. Dixon JS, Bird HA, Sitton NG, Pickup ME. Wright V, C-reactive protein in the serial assessment of disease activity in rheumatoid arthritis. Scand J Rheumatol 1984; 13:39-44.
18. Cush JJ, Lipsky PE, Posthelthwaite AE, Schrohenloher RE, Saway A, Koopman WJ. Correlation of serologic indicators of inflammation with effectiveness of nonsteroidal antiinflammafory drug therapy in rheumatoid arthritis. Arthritis Rheum 1990; 33:19-28.
19. Kremer JM, Jubiz W, Michalek A, et al. Fish-oil supplementation in active rheumatoid arthritis. Ann Intern Med 1987; 106:497-503.
20. Deehan DJ, Heys S, Simpson W, et al. Correlation of cytokines serum cytokine and acute phase reactant levels with alterations in weight and serum albumin in patients receiving immunotherapy with IL-2. Clin Exp Immunol 1994; 95:366-372.
21. O'Riordain MG, Ross JA, Fearon KCH, et al. Insulin and the counter-regulatory hormones influence acute phase protein production in the human hepatocyte. Am J Physiol 1995; 269:E323-E330.
22. Kushner I. The phenomenon of the acute phase response. Ann N Y Acad Sci 1982; 389:39-48.
23. Akira S, Kishimoto T. IL-6 and NF-IL-6 in acute phase response and viral infection. Immunol Rev 1992; 127:25-50.
24. Yamazaki K, Hamazaki T. Changes in fatty acid composition in rat blood and organs after infusion of eicosapentaenoic acid ethyl ester. Biochim Biophys Acta 1992; 1128:35-43.
25. Falconer JS, Ross JA, Fearon KCH (1994). A phase II study of ganiina-linolenic acid in pancreatic cancer and its effect on immune function and cytokine production. In: D Horrobin, ed. New Approaches to Cancer Treatment. Churchill-Livingstone; 1994:68-78.
26. Clamp AG, Grimble RF. The effects of fatty acids on the inflammatory response to cytokines by cultured rat hepatocytes. Proc Nutr Soc 1994; 53:184A.
27. Clamp AG, Grimble RF. Fatty acids modulate the affinity of the tumour necrosis factor-α (TNF-α) receptor in cultured rat hepatocytes. Proc Nutr Soc 1994; 53:180A.
28. Clamp AG, Grimble RF. Dietary lipid manipulation influences phospholipid class distribution in the rat hepatocyte plasma membrane. Proc Nutr Soc 1994; 53:35A.
29. Ferreti A, Flanagan VP, Modification of prostaglandin metabolism in vivo by long chain omega-3 polyunsaturates. Biochim Biophys Acta 1990; 1045:299-301.
30. Kunkel SL, Spengler M, May MA, et al. Prostaglandin E2 regulates macrophage-derived tumour necrosis factor gene expression, J Biol Chem 1988; 263:5380-5384.
31. Spengler RN, Spengler ML, Stricter RM, Modulation of tumour necrosis factor-α gene expression. J Immunol 1989; 142:4346-4350.
32. Kunkel SL. Chensue SW, Phan SH. Prostaglandins as endogenous mediators of interleukin-1 production. J Immunol 1986: 136:186-192.
33. Roland CR, GOSS JA, Mangino MJ. et al. Autoregulation by eicosanoids of human Kupffer cell secretory products, Ann Surg 1994; 219:389-399.
34. West MA, Manthei R, Bubrick MP. Autoregulation of hepatic macrophage activation in sepsis. J Trauma 1993; 34:473-480.
35. Goss JA, Mangino MJ. Flye MW. Prostaglandin E2 production during hepatic regeneration downregulates Kupffer cell IL-6 production. Ann Surg 1992; 215:553-559.
36. Stahl N, Boulton TG, Farruggella T, et al. Association and activation of Jak-Tyk kinases by CNTF-LIF-QSM-IL-6 beta receptor components. Science 1994; 263:92-95.