Intratympanic gentamicin for treatment of intractable Meniere's disease: A preliminary report

Laryngoscope

Volumn 107, Issue 1, 1997, Pages 49-55

  Rauch, Steven D ^a   Oas, John G ^a  

^a MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

Author keywords

Gentamicin; Intratympanic therapy; Meniere's disease; Vertigo

Indexed keywords

GENTAMICIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG EFFECT; DRUG EFFICACY; FEMALE; HEARING LOSS; HUMAN; MALE; MENIERE DISEASE; PRIORITY JOURNAL; TOPICAL DRUG ADMINISTRATION; VERTIGO;

ADMINISTRATION, TOPICAL; ADULT; AGED; ANTI-BACTERIAL AGENTS; FEMALE; GENTAMICINS; HUMANS; MALE; MENIERE'S DISEASE; MIDDLE AGED; TREATMENT OUTCOME; TYMPANIC MEMBRANE; VESTIBULAR FUNCTION TESTS;

EID: 0031033323     PISSN: 0023852X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005537-199701000-00012     Document Type: Article

References (16)

1. Schuknecht HF. Ablation therapy in the management of Meniere's disease. Acta Otolaryngol [Suppl] 1957;132:1-42.
2. Sala T. Transtympanic administration of aminoglycosides in patients with Meniere's disease. Arch Otorhinolaryngol 1988;245:293-6.
3. Ödkvist LM. Middle ear ototoxic treatment for inner ear disease. Acta Otolaryngol [Suppl] 1989;457:83-6.
4. Magnusson M, Padoan S, Karlberg M, Johansson R. Delayed onset of ototoxic effects of gentamicin in treatment of Meniere's disease. Acta Otolaryngol [Suppl] 1991;481:610-2.
5. Magnusson M, Padoan S. Delayed onset of ototoxic effects of gentamicin in treatment of Meniere's disease. Rationale for extremely low dose therapy. Acta Otolaryngol 1991;111:671-6.
6. Magnusson M, Padoan S, Karlberg M, Johansson R. Delayed onset of ototoxic effects of gentamicin in patients with Meniere's disease. Acta Otolaryngol [Suppl] 1991;485:120-2.
7. Nedzelski JM, Schessel DA, Bryce GE, Pfleiderer AG. Chemical labyrinthectomy: local application of gentamicin for the treatment of unilateral Meniere's disease. Am J Otol 1992;13:18-22.
8. Nedzelski JM, Bryce GE, Pfleiderer AG. Treatment of Meniere's disease with topical gentamicin: a preliminary report. J Otolaryngol 1992;21:95-101.
9. Nedzelski JM, Chiong CM, Fradet G, Schessel DA, Bryce GE, Pfleiderer AG. Intratympanic gentamicin instillation as treatment of unilateral Meniere's disease: update of an ongoing study. [Review]. Am J Otol 1993;14:278-82.
10. Pyykkö I, Ishizaki H, Kaasinen S, Aalto H. Intratympanic gentamicin in bilateral Meniere's disease. Otolaryngol Head Neck Surg 1994;110:162-7.
11. Committee on Hearing and Equilibrium. Committee on Hearing and Equilibrium Guidelines for the Diagnosis and Evaluation of Therapy in Meniere's Disease. Otolaryngol Head Neck Surg 1995;113:181-5.
12. Wall CI, Black FO. Algorithms for the clinical analysis of nystagmus eye movements. IEEE Trans Biomed Eng 1981;28:638-10.
13. Dimitri PS, Wall CI, Oas JG. Classification of human rotational test results using parametric modeling and multivariate statistics. Acta Otolaryngol 1996;116:497-506.
14. Schacht J. Biochemical basis of aminoglycoside ototoxicity. Otolaryngol Clin North Am 1993;26:845-56.
15. Pender DJ. Gentamicin tympanoclysis: effects on the vestibular secretory cells. Ant J Otolaryngol 1985;6: 358-67.
16. Baloh RW, Honrubia V. Clinical neurophysiology of the vestibular system. 2nd ed. Philadelphia: Davis, 1990.