-
1
-
-
0004220273
-
The concentratio-related distribution of cyclosporine in blood
-
Annesley, T.M., Giacherio, D.A. and Feldkamp, C.S. (1986) The concentratio-related distribution of cyclosporine in blood. J. Clin. Immunoassay 9, 53.
-
(1986)
J. Clin. Immunoassay
, vol.9
, pp. 53
-
-
Annesley, T.M.1
Giacherio, D.A.2
Feldkamp, C.S.3
-
3
-
-
0025740680
-
Cyclosporin a and FK-506 both affect DNa binding of regulatory nuclear proteins to the human interleukin-2 promoter
-
Baumann, G., Geisse, S. and Sullivan, M. (1991) Cyclosporin A and FK-506 both affect DNA binding of regulatory nuclear proteins to the human interleukin-2 promoter. New Biol. 3, 270.
-
(1991)
New Biol.
, vol.3
, pp. 270
-
-
Baumann, G.1
Geisse, S.2
Sullivan, M.3
-
4
-
-
0026693772
-
Cyclosporine and its analogue SDZ IMM 125 mediate very similar effects on T-cell activation - A comparative analysis in vitro
-
Baumann, G., Andersen, E., Quesniaux, V. and Eberle, M.K. (1992) Cyclosporine and its analogue SDZ IMM 125 mediate very similar effects on T-cell activation - a comparative analysis in vitro. Transplant. Proc. 24, 43.
-
(1992)
Transplant. Proc.
, vol.24
, pp. 43
-
-
Baumann, G.1
Andersen, E.2
Quesniaux, V.3
Eberle, M.K.4
-
5
-
-
0026602240
-
The efficacy of cyclosporin A, FK-506 and prednisolone to modify the adoptive transfer of experimental allergic encephalomyelitis (EAE)
-
Bolton, C. (1992) The efficacy of cyclosporin A, FK-506 and prednisolone to modify the adoptive transfer of experimental allergic encephalomyelitis (EAE). Agents Actions 35, 79.
-
(1992)
Agents Actions
, vol.35
, pp. 79
-
-
Bolton, C.1
-
6
-
-
0017157814
-
Biological effect of cyclosporin A: A new antilymphocytic agent
-
Borel, J.F., Feurer, C., Gubler, H.U. and Stähelin, H. (1976) Biological effect of cyclosporin A: a new antilymphocytic agent. Agents Actions 6, 468.
-
(1976)
Agents Actions
, vol.6
, pp. 468
-
-
Borel, J.F.1
Feurer, C.2
Gubler, H.U.3
Stähelin, H.4
-
7
-
-
0025284234
-
Hawk's Cay meeting on therapeutic drug monitoring of cyclosporine
-
Consensus Document: (1990) Hawk's Cay meeting on therapeutic drug monitoring of cyclosporine. Transplant. Proc. 22, 1357.
-
(1990)
Transplant. Proc.
, vol.22
, pp. 1357
-
-
-
8
-
-
0026523345
-
Synthesis of the main metabolite (OL-17) of cyclosporin A
-
Eberle, M.K. and Nuninger, F. (1992) Synthesis of the main metabolite (OL-17) of cyclosporin A. J. Org. Chem. 57, 2689.
-
(1992)
J. Org. Chem.
, vol.57
, pp. 2689
-
-
Eberle, M.K.1
Nuninger, F.2
-
9
-
-
0026560491
-
The optimal use of cyclosporin a in autoimmune diseases
-
erratum appeared in J. Autoimmun. (1992) 5, 545
-
Feutren, G. (1992) The optimal use of cyclosporin A in autoimmune diseases [erratum appeared in J. Autoimmun. (1992) 5, 545]. J. Autoimmun. 5 (suppl. A), 183.
-
(1992)
J. Autoimmun.
, vol.5
, Issue.SUPPL. A
, pp. 183
-
-
Feutren, G.1
-
10
-
-
0026027135
-
Assessment of the biological activity of cyclosporine metabolites using the human Jurkat cell line
-
Freed, B.M., Stevens, C., Brooks, C., Cramer, S., Lempert, N. and Rosano, T.G. (1991) Assessment of the biological activity of cyclosporine metabolites using the human Jurkat cell line. Transplant. Proc. 23, 980.
-
(1991)
Transplant. Proc.
, vol.23
, pp. 980
-
-
Freed, B.M.1
Stevens, C.2
Brooks, C.3
Cramer, S.4
Lempert, N.5
Rosano, T.G.6
-
11
-
-
0026547953
-
Cyclosporin monitoring: Its role in autoimmune indications
-
Holt, D.W. and Johnston, A. (1992) Cyclosporin monitoring: its role in autoimmune indications. J. Autoimmun. 5, 177.
-
(1992)
J. Autoimmun.
, vol.5
, pp. 177
-
-
Holt, D.W.1
Johnston, A.2
-
12
-
-
0002418693
-
Pharmacokinetics and monitoring of cyclosporin A
-
A.W. Thomson and T.E. Starzl (Eds.), Edward Arnold, London
-
Holt, D.W. and Johnston, A. (1994) Pharmacokinetics and monitoring of cyclosporin A. In: A.W. Thomson and T.E. Starzl (Eds.), Immunosuppressive Drugs-Developments in Anti-Rejection Therapy. Edward Arnold, London, p. 37.
-
(1994)
Immunosuppressive Drugs-Developments in Anti-Rejection Therapy
, pp. 37
-
-
Holt, D.W.1
Johnston, A.2
-
13
-
-
0023245677
-
FK-506, a novel immunosuppressant isolated from a streptomyces. I. Fermentation, isolation, physico-chemical characteristics
-
Kino, T., Hatanaka, H., Hashimoto, M., Nishiyama, M., Goto, T., Okuhara, M., Kohsaka, M., Aoki, M. and Imanaka, H. (1987) FK-506, a novel immunosuppressant isolated from a streptomyces. I. Fermentation, isolation, physico-chemical characteristics. J. Antibiot. 40, 1249.
-
(1987)
J. Antibiot.
, vol.40
, pp. 1249
-
-
Kino, T.1
Hatanaka, H.2
Hashimoto, M.3
Nishiyama, M.4
Goto, T.5
Okuhara, M.6
Kohsaka, M.7
Aoki, M.8
Imanaka, H.9
-
14
-
-
0028335905
-
Reduced inter- and intraindividual variability in cyclosporine pharmacokinetics from a microemulsion formulation
-
Kovarik, J.M., Mueller, E.A., van Bree, J.B., Tetzloff, W. and Kutz, K. (1994) Reduced inter- and intraindividual variability in cyclosporine pharmacokinetics from a microemulsion formulation. J. Pharm. Sci. 83, 444.
-
(1994)
J. Pharm. Sci.
, vol.83
, pp. 444
-
-
Kovarik, J.M.1
Mueller, E.A.2
Van Bree, J.B.3
Tetzloff, W.4
Kutz, K.5
-
15
-
-
0001240467
-
Cyclosporin a inhibits T-cell growth factor gene expression at the level of mRNa transcription
-
Kroencke, M., Leonard, W.J., Depper, M.J., Arya, S.K., Wong-Staal, F., Gallo, R.C., Waldmann, T.A. and Greene, T.C. (1984) Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription. Proc. Natl. Acad. Sci. USA 81, 5214.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 5214
-
-
Kroencke, M.1
Leonard, W.J.2
Depper, M.J.3
Arya, S.K.4
Wong-Staal, F.5
Gallo, R.C.6
Waldmann, T.A.7
Greene, T.C.8
-
16
-
-
0025694815
-
The actions of cyclosporin a and FK506 suggest a novel step in the activation of T lymphocytes
-
Mattila, P.S., Ullman, K.S., Fiering, S., Emmel, E.A., McCutcheon, M., Crabtree, G.R. and Herzenberg, L.A. (1990) The actions of cyclosporin A and FK506 suggest a novel step in the activation of T lymphocytes. EMBO J. 9, 4425.
-
(1990)
EMBO J.
, vol.9
, pp. 4425
-
-
Mattila, P.S.1
Ullman, K.S.2
Fiering, S.3
Emmel, E.A.4
McCutcheon, M.5
Crabtree, G.R.6
Herzenberg, L.A.7
-
17
-
-
0028329964
-
Improved dose linearity of cyclosporine pharmacokinetics from a microemulsion formulation
-
Mueller, E.A., Kovarik, J.M., van Bree, J.B., Tetzloff, W., Grevel, J. and Kutz, K. (1994) Improved dose linearity of cyclosporine pharmacokinetics from a microemulsion formulation. Pharm. Res. 11, 301.
-
(1994)
Pharm. Res.
, vol.11
, pp. 301
-
-
Mueller, E.A.1
Kovarik, J.M.2
Van Bree, J.B.3
Tetzloff, W.4
Grevel, J.5
Kutz, K.6
-
18
-
-
0025821379
-
Considerations for monitoring cyclosporine in transplant recipients
-
Napoli, K.L. and Kahan, B.D. (1991) Considerations for monitoring cyclosporine in transplant recipients. Clin. Lab. Med. 11, 671.
-
(1991)
Clin. Lab. Med.
, vol.11
, pp. 671
-
-
Napoli, K.L.1
Kahan, B.D.2
-
19
-
-
0023205385
-
Cyclophilin binds to the region of cyclosporine involved in its immunosuppressive activity
-
Quesniaux, V.F.J., Schreier, M.H., Wenger, R.M., Hiestand, P.C., Harding, M.W. and van Regenmortel, M.H.V. (1987) Cyclophilin binds to the region of cyclosporine involved in its immunosuppressive activity. Eur. J. Immunol. 17, 1359.
-
(1987)
Eur. J. Immunol.
, vol.17
, pp. 1359
-
-
Quesniaux, V.F.J.1
Schreier, M.H.2
Wenger, R.M.3
Hiestand, P.C.4
Harding, M.W.5
Van Regenmortel, M.H.V.6
-
20
-
-
0025268491
-
Monoclonal antibodies to cyclosporin are representative of the major antibody populations present in antisera of immunized mice
-
Quesniaux, V.F., Schmitter, D., Schreier, M.H. and Van Regenmortel, M.H. (1990) Monoclonal antibodies to cyclosporin are representative of the major antibody populations present in antisera of immunized mice. Mol. Immunol. 27, 227.
-
(1990)
Mol. Immunol.
, vol.27
, pp. 227
-
-
Quesniaux, V.F.1
Schmitter, D.2
Schreier, M.H.3
Van Regenmortel, M.H.4
-
21
-
-
0025972415
-
A preliminary study to evaluate an in vitro assay for determining patient whole blood immunosuppressive cyclosporine a and metabolite activity: Comparison with cytosolic binding assays using cyclophilin or a 50-kilodalton binding protein, and the Abbott TDx cyclosporine a parent, and parent and metabolites assays
-
Russell, R.L., Donnelly, J.G., Palaszynski, E.W., Chan, M.M. and Soldin, S.J. (1991) A preliminary study to evaluate an in vitro assay for determining patient whole blood immunosuppressive cyclosporine A and metabolite activity: comparison with cytosolic binding assays using cyclophilin or a 50-kilodalton binding protein, and the Abbott TDx cyclosporine A parent, and parent and metabolites assays. Ther. Drug Monit. 13, 32.
-
(1991)
Ther. Drug Monit.
, vol.13
, pp. 32
-
-
Russell, R.L.1
Donnelly, J.G.2
Palaszynski, E.W.3
Chan, M.M.4
Soldin, S.J.5
-
22
-
-
0004136246
-
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
-
(1989)
Molecular Cloning: a Laboratory Manual
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
23
-
-
0027964239
-
Human cyclophilin C: Primary structure, tissue distribution, and determination of binding specificity for cyclosporins
-
Schneider, H., Charara, N., Schmitz, R., Wehrli, S., Mikol, V., Zurini, M.G., Quesniaux, V.F. and Movva, N.R. (1994) Human cyclophilin C: primary structure, tissue distribution, and determination of binding specificity for cyclosporins. Biochemistry 33, 8218.
-
(1994)
Biochemistry
, vol.33
, pp. 8218
-
-
Schneider, H.1
Charara, N.2
Schmitz, R.3
Wehrli, S.4
Mikol, V.5
Zurini, M.G.6
Quesniaux, V.F.7
Movva, N.R.8
-
24
-
-
0026575932
-
The mechanism of action of cyclosporin a and FK506
-
Schreiber, S.L. and Crabtree, G.R. (1992) The mechanism of action of cyclosporin A and FK506. Immunol. Today 13, 136.
-
(1992)
Immunol. Today
, vol.13
, pp. 136
-
-
Schreiber, S.L.1
Crabtree, G.R.2
-
25
-
-
0342321233
-
Long-Term Culture and Cloning of Specific Helper T Cells
-
I. Lefkovits and B. Pernis (Eds.), Academic Press, New York
-
Schreier, M.H. and Tees, R. (1981) Long-Term Culture and Cloning of Specific Helper T Cells. In: I. Lefkovits and B. Pernis (Eds.), Immunological Methods, Vol. 2. Academic Press, New York, p. 263.
-
(1981)
Immunological Methods
, vol.2
, pp. 263
-
-
Schreier, M.H.1
Tees, R.2
-
26
-
-
0028869086
-
Rapamune (Sirolimus, rapamycin): An overview and mechanism of action
-
Sehgal, S.N. (1995) Rapamune (Sirolimus, rapamycin): an overview and mechanism of action. Ther. Drug Monit. 17, 660.
-
(1995)
Ther. Drug Monit.
, vol.17
, pp. 660
-
-
Sehgal, S.N.1
-
27
-
-
0024318981
-
Advances in cyclosporine pharmacology, measurement, and therapeutic monitoring
-
Shaw, L.M. (1989) Advances in cyclosporine pharmacology, measurement, and therapeutic monitoring. Clin. Chem. 35, 1299.
-
(1989)
Clin. Chem.
, vol.35
, pp. 1299
-
-
Shaw, L.M.1
-
28
-
-
0026668716
-
FK-506 and cyclosporin A: Immunosuppressive mechanism of action and beyond
-
Siekierka, J.J. and Sigal, N.H. (1992) FK-506 and cyclosporin A: immunosuppressive mechanism of action and beyond. Curr. Opin. Immunol. 4, 548.
-
(1992)
Curr. Opin. Immunol.
, vol.4
, pp. 548
-
-
Siekierka, J.J.1
Sigal, N.H.2
-
29
-
-
0026016210
-
Inter- and intra-subject variation of the suppression of mitogen-induced proliferation of human lymphocytes by cyclosporin-A: Reduction of response with delayed addition may be relevant to timing of therapy
-
Spiers, E.M. and Beck, J.S. (1991) Inter- and intra-subject variation of the suppression of mitogen-induced proliferation of human lymphocytes by cyclosporin-A: reduction of response with delayed addition may be relevant to timing of therapy. Int. J. Immunopharmacol. 13, 245.
-
(1991)
Int. J. Immunopharmacol.
, vol.13
, pp. 245
-
-
Spiers, E.M.1
Beck, J.S.2
-
30
-
-
0023508097
-
Cyclosporine: Structure, pharmacokinetics and therapeutic drug monitoring
-
Vine, W. and Bowers, L.D. (1987) Cyclosporine: structure, pharmacokinetics and therapeutic drug monitoring [Review]. Crit. Rev. Clin. Lab. Sci. 25, 275.
-
(1987)
Crit. Rev. Clin. Lab. Sci.
, vol.25
, pp. 275
-
-
Vine, W.1
Bowers, L.D.2
-
31
-
-
0000852668
-
Structure of cyclosporine and its metabolites: Total synthesis of cyclosporine metabolites formed by oxidation at positions 4 and 9 of cyclosporine. Preparation of leucine-4-cyclosporine, (γ-hydroxy)-N-methyl-leucine-9-cyclosporine and leucine-4-(γ-hydroxy)-N-methyl-leucine-9-cyclosporine
-
Wenger, R.M., Martin, K., Timbers, C. and Tromelin, A. (1992) Structure of cyclosporine and its metabolites: total synthesis of cyclosporine metabolites formed by oxidation at positions 4 and 9 of cyclosporine. Preparation of leucine-4-cyclosporine, (γ-hydroxy)-N-methyl-leucine-9-cyclosporine and leucine-4-(γ-hydroxy)-N-methyl-leucine-9-cyclosporine. Chimia 46, 314.
-
(1992)
Chimia
, vol.46
, pp. 314
-
-
Wenger, R.M.1
Martin, K.2
Timbers, C.3
Tromelin, A.4
-
32
-
-
0027316918
-
Molecular mechanisms of immunosuppression by cyclosporins
-
Zenke, G., Baumann, G., Wenger, R., Hiestand, P., Quesniaux, V., Andersen, E. and Schreier, M.H. (1993) Molecular mechanisms of immunosuppression by cyclosporins. Ann. N.Y. Acad. Sci. 685, 330.
-
(1993)
Ann. N.Y. Acad. Sci.
, vol.685
, pp. 330
-
-
Zenke, G.1
Baumann, G.2
Wenger, R.3
Hiestand, P.4
Quesniaux, V.5
Andersen, E.6
Schreier, M.H.7
|