Distribution of apolipoprotein e gene polymorphisms in japanese patients with alzheimer’s disease and in japanese centenarians

Human Heredity

Volumn 47, Issue 1, 1997, Pages 22-26

  Yamagata, Zentaro ^a   Asada, Takashi ^a   Kinoshita, Akemi ^a   Zhang, Yingning ^a   Asaka, Akio ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

Alzheimer s disease; Apolipoprotein E; Centenarian; Gene polymorphism

Indexed keywords

APOLIPOPROTEIN E; APOLIPOPROTEIN E2; APOLIPOPROTEIN E4;

AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENETIC SUSCEPTIBILITY; HUMAN; HUMAN CELL; JAPAN; MAJOR CLINICAL STUDY; MALE; ONSET AGE; POLYMERASE CHAIN REACTION; POPULATION GENETICS;

AGED; AGED, 80 AND OVER; ALLELES; ALZHEIMER DISEASE; APOLIPOPROTEINS E; HUMANS; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; RISK FACTORS;

EID: 0031032999     PISSN: 00015652     EISSN: 14230062     Source Type: Journal    
DOI: 10.1159/000154384     Document Type: Article

References (17)

1. Corder EL, Sauders AM, Strittmatter WJ, Schmcchcl DE, Gaskell PC, Small GW, Roses AD, Haines JL, Pericak-Vance MA: Gene dose of apolipoprotcin E type 4 allele and the risk of Alzheimer's disease in laic onset families, Science 1993: 261:921-923.
2. Strittmattcr WJ, Sauders AM, Schmcchcl D, Pericak-Vance M, Enghild J, Salvcsen GS, Roses AD: Apolipoprotcin E: High-avidity binding to B-antyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease, Proe Natl Acad Sci USA 1993:90: 1977-1981.
3. Van Duijn CM, Knijl TP, Cruts M, Wehncrt A, Havakcs LM, Holman A, Van Brocckhovcn C: Apolipopro-lein E4 allele in a population-based study of early-onsct Alzheimer's disease, Nat Genet 1994:7:74-78.
4. Hixon JE, Vernier DT: Restriction isotvping of human apolipoprotcin E by gene amplification and cleavage with Aal, J Lipid Res 1990:31: 545-548.
5. Tsukamoto K, Watanabe T, Matsushima T, Kinoshita M, Kalo H, Hashimoto Y, Kurokawa K, Teramoto T: Determination by PC'R-RFLP of apoE genotype in a Japanese population, J Lab Clin Med 1993:121: 598-602.
6. Schellenberg GD, Bird TD, Wijs-man EM, Orr HT, Anderson L, Nemens E, White JA, Bonnycastle L, Weber JL, Alonso EM, Potter H, Heston LL, Martin GM: Genetic linkage evidence for a familial Alzheimer’s disease loeus on chromosome 14. Science 1992:258:668-671.
7. St George-Hvslop PH, Tanzi RE, Polinskv RJ, Hains JE, Nee L, Watkins PC, Myers RH, Feldman RG, Pollen D, Drachman D, Gowdon J, Bruni A, Foncin JF, Salmon D, Frömmelt P, Amaducci L, Sorbi S, Piaccntini S, Stewart GD, Horrs WJ, Conncally PM, Gusella JF: The genetic defect causing familial Alzheimer's disease maps on chromosome 21. Science 1987:235:885-890.
8. Goate A, Chartier-llarlin MC, Mul-lan M, Brown J, Crawford F, Fidani L, Guiffra L, Haynes A, Irving N, James L, Mant R, Newton P, Rooke K, Roques P, Talbot C, Pericak-Vance M, Roses A, Williamson R, Rossor M, Owen M, Hardy J: Segregation of missense mutation in the amyloid precursor protein gene with familial Alzheimer’s disease, Nature 1991:349:704-706.
9. Pericak-Vancc MA, Bcboul JL, Gas-kell PC, Yamaoka LH, Hung WY, Alberts MJ, Walker AP, Bartlett RJ, Haynes CA, Welsh KA, Earl NL, Hcyman A, Clark CM, Roses AD: Linkage studies in familial Alzheimer disease: Evidence for chromosome 19 linkage, Am J Hum Genet 1991:48:1034-1050.
10. Borgaonkar DS, Schmidt LC, Marlin SE, Kanzer MD, Edelsohn L, Growdon J, Farrcr LA: Linkage of late-onset Alzheimer’s disease with apolipoprotein E type 4 on chromosome 19. Lancet 1993:342:625.
11. Poirier J, Davignon J, Bothillicr D, Kogan S, Bertrand P, Gauthier S: Apolipoprotein E polymorphism and Alzheimer's disease, Lancet 1993;342:697-699.
12. Ueki A, Kawano M, Namba Y, Kawakanti M, Ikeda K: A high frequency of apolipoprotein E4 iso-protein in Japanese patients with late-onsct nonfamilial Alzheimer’s disease, Ncurosci Lett 1993:163: 166-168.
13. Corder EH, Saunders AM, Riseh NJ, Strittmatter WJ, Schmechel DE, Gaskcll Jr PC, Rimmler JB, Locke PA, Conncally PM, Schmader KE, Small GW, Roses AD, Haines JL, Pericak-Vancc MA: Protective effect of apoliporoicin E type 2 allele for late onset Alzheimer disease, Nat Genet 1994:7:180-184.
14. Dai XY, Nanko S, Hattori M, Fukuda R, Nagata K, Isse K, Ueki A, Kazamatsuri H: Association of apolipoprotein E4 with sporadic Alzheimer's disease is more pronounced in early onset type, Neuro-sci Lett 1994:175:74-76.
15. Yoshizawa T, Yamakawa-Kobava-shi K, Komatsuzaki Y, Arinami T, Oguni E, Mizusawa H, Shoji S, Ha-maguchi II: Dose-depenent association of apolipoprotein E allele epsilon 4 with late-onset, sporadic Alzheimer's disease, Ann Neurol 1994: 36:656-659.
16. Kawamata J, Tanaka S, Shimohama S, Ucda K, Kimura J: Apolipoprotein E polymorphism in Japanese patients with Alzheimer's disease or vascular dementia, J Neurol Ncuro-surg Psychiatry 1994:57:1414-1416.
17. Okuizumi K, Onodera O, Tanaka H, Kobayashi H, Tsuji S, Takahashi H, Oyanagi K, Seki K, Naruse S, Mizusawa H, Kanazawa I: ApoE-s4 and carly-onset Alzheimer’s, Nat Genet 1994;7:10-11.