메뉴 건너뛰기




Volumn 38, Issue 3, 1997, Pages 303-304

An approach to chiral tri-substituted olefins: Synthesis of the C(1)-C(7) segment of halichomycin

Author keywords

[No Author keywords available]

Indexed keywords

HALICHOMYCIN; MACROLIDE; UNCLASSIFIED DRUG;

EID: 0031032857     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(96)02338-6     Document Type: Article
Times cited : (7)

References (18)
  • 7
    • 0342569442 scopus 로고    scopus 로고
    • note
    • 13C (125 MHz) NMR spectra, as well as appropriate parent ion identification by high-resolution mass spectrometry.
  • 12
    • 0000604671 scopus 로고
    • Heathcock has investigated 3-thiopropenals in stereoselective aldol reactions and reported that they can be selectively manipulated to produce either syn-or anti-aldol products, see: Danda, H.; Hansen, M. M.; Heathcock, C. H. J. Org. Chem. 1990, 55, 173.
    • (1990) J. Org. Chem. , vol.55 , pp. 173
    • Danda, H.1    Hansen, M.M.2    Heathcock, C.H.3
  • 15
    • 0342569438 scopus 로고    scopus 로고
    • note
    • Given that the binary mixture is reduced to a single product upon reductive removal of the chiral auxiliary, this byproduct is likely derived from dehydration of the anti-or non-Evans syn aldol product.
  • 16
    • 0342569437 scopus 로고    scopus 로고
    • Reference 2a
    • For the synthesis of (+)-9, see: (a) Reference 2a.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.