Loss of hippocampal CA1 neurons and learning impairment in subicular lesioned rats

Brain Research

Volumn 745, Issue 1-2, 1997, Pages 121-126

  Govindaiah, ^a   Shankaranarayana Rao, B S ^a   Raju, T R ^a   Meti, B L ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

Author keywords

Acquisition; Electrolytic lesion; Hippocampus; Ibotenic acid lesion; Operant learning; Retention; Subiculum

Indexed keywords

IBOTENIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CONTROLLED STUDY; HIPPOCAMPUS; HISTOLOGY; INSTRUMENTAL CONDITIONING; LEARNING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SUBICULUM;

ANIMALS; AXONS; CELL COUNT; CONDITIONING, OPERANT; ELECTROSHOCK; EXCITATORY AMINO ACID ANTAGONISTS; HIPPOCAMPUS; IBOTENIC ACID; LEARNING DISORDERS; MALE; MEMORY; NERVE DEGENERATION; NEURONS; RATS; RATS, WISTAR; STEREOTAXIC TECHNIQUES;

EID: 0031032489     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)01135-3     Document Type: Article

References (30)

1. Alvarado, M.C and Rudy, J.W., A comparison of kainic acid plus colchicine and ibotenic acid-induced hippocampal formation damage on four configural tasks in rats, Behav. Neurosci., 109 (1995) 1052-1062.
2. Amaral, D.G., Dolorfo, C. and Alvarez-Royo, P., Organization of CA1 projections to the subiculum: a PHA-L analysis in the rats, Hippocampus, 1 (1991) 415-436.
3. Bouffard, J. and Jarrard, L.E., Acquisition of a complex place task in rats with selective ibotenate lesions of hippocampal formation: combined lesions of subiculum and entorhinal cortex vs. hippocampus, Behav. Neurosci., 102 (1988) 828-834.
4. Cho, Y.H and Jaffard R., Spatial location learning in mice with ibotenate lesions of entorhinal cortex or subiculum, Neurobiol. Learning Memory, 64 (1995) 285-290.
5. Hirsh, The hippocampus, conditional operations and cognition, Physiol. Psychol., 8 (1986) 175-182.
6. Jarrard, L.E., Selective hippocampal lesions: differential effects on performance by rats of spatial task with pre- operative and post-operative training, J. Comp. Physiol. Psychol., 92 (1978) 1119-1127.
7. Jarrard, L.E., Okaichi, H., Gold Schmidt, R. and Steward, O., On the role of hippocampal connections in the performance of place and cue tasks: comparison with damage to hippocampus, Behav. Neurosci., 98 (1984) 946-954.
8. Jarrard, L.E., Felton, J., Rawlins, J.N.P., Sinden, J.D. and Gray, J.A., The effects of intrahippocampal ibotenate on resistance to extinction after continuous or partial reinforcement, Exp. Brain Res., 61 (1986) 519-530.
9. Jarrard, L.E., Selective hippocampal lesions and behavior: Implications for current research and theorizing. In R.L. Isaacson and K.H. Pribram (Eds.), The Hippocampus, Vol. 4, Plenum Press, New York, 1986, pp. 93-126.
10. Jarrard, L.E., On the use of ibotenic acid to lesion selectively different components of the hippocampal formation, J. Neurosci. Methods, 29 (1989) 251-259.
11. Johnson, L.S. and Jarrard, L.E., Effects of ibotenate lesions of the CA1 hippocampal cell field on acquisition of complex place and cue tasks in the rat, Virginia J. Sci., 37 (1986) 135.
12. Kohler, C. and Schwartz, R., Comparison of ibotenate and kainate neurotoxicity in rat brain: A histological study, Neuroscience, 8 (1983) 819-835.
13. Kohler, C., Intrinsic projections of the retrohippocampal regions in the rat brain. The subicular complex, J. Comp. Neurol., 236 (1985) 504-522.
14. Morris, R.G.M., Hagan, J.J. and Rawlins, J.N.P., Allocentric spatial learning by hippocampectomized rats: a further test of the 'spatial mapping' and 'working memory' theories of hippocampal functions, Q. J. Exp. Psychol., 38 (1986) 365-395.
15. Morris, R.G.M., Schenk, F.T. and Jarrard, L.E., Ibotenate lesions of hippocampus and/or subiculum: Dissociating components of allocentric spatial learning, Eur. J. Neurosci., 2 (1990) 1016-1028.
16. O'Keefe, J. and Nadel, L., The Hippocampus as a Cognitive Map, Oxford Univ. Press, London, 1978.
17. Olton, D.S., Becker, J.T. and Handelmann, G.E., Hippocampus, space and memory, Brain Behav. Sci., 2 (1979) 313-365.
18. Olsen, G.M., Schecl-Kruger, J., Moller, A. and Jensen, L.H., Relation of spatial learning of rats in the Morris water maze task to the number of viable CAl neurons following four vessel occlusion, Behav. Neurosci., 108 (1994) 681-690.
19. Paxinos, G. and Watson, C., The Rat Brain in Stereotaxic Coordinates, Academic Press, New York, 1982.
20. Rawlins, J.N.P., Associations across time: The hippocampus as a temporary memory store, Brain Behav. Sci., 8 (1985) 479-496.
21. Schenk, F.T. and Morris R.G.M., Dissociation between components of spatial memory in rats after recovery from the effects of retrohippocampal lesions, Exp. Brain Res., 58 (1985) 11-28.
22. Sinden, J.D., Rawlins, J.N.P., Jafferry, A., Gray and Jarrard, L.E., Selective cytotoxic lesions of the hippocampal formation and DRL performance in rats, Behav. Neurosci., 100 (1986) 320-329.
23. Swanson, L.W. and Cowan, W.M., An autoradiographic study of the organization of the efferent connections of the hippocampal formation in the rat, J. Comp. Neurol., 172 (1977) 49-84.
24. Taube, J.S., Muller, R.V. and Ranck, J.B. Jr., Head direction cells recorded from the post subiculum in freely moving rats. I. Description and quantitative analysis, J. Neurosci., 10 (1990) 420-435.
25. Taube, J.S., Muller, R.V. and Ranck, J.B., Jr., Head direction cells recorded from the post subiculun in freely moving rats. II. The effects of environmental manipulation, J. Neurosci., 10 (1990) 436-447.
26. Taube, J.S., Kesslak, J.P. and Cotman, C.W., Lesions of the rat postsubiculum impair performance on spatial tasks, Behav. Neural Biol., 57 (1992) 131-143.
27. Volpe, B.T., Davis, H.P., Towle, A. and Dunlop, W.P., Loss of hippocampal CA1 pyramidal neurons correlates with memory impairment in rats with ischemic or neurotoxic lesions, Behav. Neurosci., 106 (1992) 457-464.
28. Witter, P.P., Connectivity of the rat hippocampus. In V. Chan-palay and C. Kohler (Eds.), The Hippocampus - New Vistas, Neurology and Neurobiology, Vol. 10, A.R. Liss, New York, 1989, pp. 53-69.
29. Wood, E.R., Mumby, D.G., Pinel, J.P.J. and Phillips, A.G., Impaired object recognition in rats following ischemia induced damage to the hippocampus, Behav. Neurosci., 107 (1993) 51-62.
30. Zar, J.H., Biostatistical Analysis, Prentice-Hall Int., New Jersey, USA, 1984.