Alterations in dopamine clearance and catechol-O-methyltransferase activity by dopamine infusions in children

Critical Care Medicine

Volumn 25, Issue 1, 1997, Pages 181-189

  Allen, Elizabeth ^a,b,c   Pettigrew, Anita ^a,b,c   Frank, Dorothy ^a,b   Thompson, Suzanne ^a,b,c   Myers, Carolyn ^a,b,c   Yamashita, Toyoko ^a,b   Blumer, Jeffrey L ^a,b,c  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF VIRGINIA MEDICAL CENTER   (United States)

Author keywords

catechol O methyltransferase (COMT); congenital heart disease; dopamine; enzyme induction; pharmacokinetics

Indexed keywords

3 O METHYLDOPAMINE; CATECHOL METHYLTRANSFERASE; DOPAMINE;

AGE; ARTICLE; CHILD; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONGENITAL HEART DISEASE; CONTROLLED STUDY; CRITICAL ILLNESS; DOPAMINE BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; ENZYME ACTIVITY; FEMALE; HEART OUTPUT; HUMAN; HUMAN CELL; INFANT; INTRAVENOUS DRUG ADMINISTRATION; MALE; MONONUCLEAR CELL; PRIORITY JOURNAL; STEADY STATE; URINE VOLUME;

CATECHOL O-METHYLTRANSFERASE; CHILD; CHILD, PRESCHOOL; CRITICAL ILLNESS; DOPAMINE; FEMALE; HEART DEFECTS, CONGENITAL; HUMANS; INFANT; INFANT, NEWBORN; INFUSIONS, INTRAVENOUS; LEUKOCYTES, MONONUCLEAR; MALE;

EID: 0031032237     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-199701000-00032     Document Type: Article

References (36)

1. Zaritsky A, Chernow B: Use of catecholamines in pediatrics. J Pediatr 1984; 105:341-350
2. Lang P, Williams R, Norwood W, et al: The hemodynamic effects of dopamine in infants after corrective cardiac surgery. J Pediatr 1980; 96:630-634
3. Padbury J, Agata Y, Baylen B, et al: Dopamine pharmacokinetics in critically ill newborn infants. J Pediatr 1987; 110:293-298
4. Zaritsky A, Lotze A, Stull R, et al: Steady-state dopamine clearance in critically ill infants and children. Crit Care Med 1988; 16:217-220
5. Notterman D, Greenwald B, Moran F, et al: Dopamine clearance in critically ill infants and children: Effect of age and organ system dysfunction. Clin Pharmacol Ther 1990; 48:138-147
6. Jarnberg PO, Bengtsson L, Ekstrand J, et al: Dopamine infusion in man. Plasma catecholamine levels and pharmacokinetics. Acta Anesthesiol Scand 1981; 25:328-331
7. Eldadah M, Schwartz P, Harrison R, et al: The pharmacokinetics of dopamine in infants and children. Crit Care Med 1991; 19:1008-1011
8. Banner W, Vernon D, Dean JM, et al: Nonlinear dopamine pharmacokinetics in pediatric patients. J Pharmacol Exp Ther 1989; 249:131-133
9. Zis A, Gold P, Paul S, et al: Elevation of human plasma and platelet amine oxidase activity in response to intravenous dopamine. Life Sci 1981; 28:371-376
10. Radovick S, Dahms W, Hill J, et al: Inhibition of TSH release during dopamine (DA) infusion in children. Abstr. Pediatr Res 1986; 20:182A
11. Axelrod J, Tomchick R: Enzymatic O-methylation of epinephrine and other catechols. J Biol Chem 1958; 233: 702-705
12. Kopin I: Catecholamine metabolism: Basic aspects and clinical significance. Pharm Rev 1985; 37:333-364
13. LaBrosse EH, Axelrod J, Kety SS: O-methylation, the principal route of metabolism of epinephrine in man. Science 1958; 128:593-594
14. 3-epinephrine-d-bitartarate in normal young men. J Clin Invest 1961; 40:253-260
15. Goodall McC, Alton H: Metabolism of 3-hydroxytyramine (dopamine) in human subjects. Biochem Pharmacol 1968; 17: 905-914
16. Kadar D, Tang HY, Conn AW: Isoproterenol metabolism in children after intravenous administration. Clin Pharmacol Ther 1974; 16:789-795
17. Weinshilboum R, Raymond F: Inheritance for low erythrocyte catechol-O-methyltransferase activity in man. Am J Hum Genet 1977; 29:125-135
18. Weinshilboum R: Human erythrocyte catechol-O-methyltransferase: Correlation with lung and kidney activity. Life Sci 1978; 22:625-630
19. Sladek-Chelgren S, Weinshilboum R: Catechol-O-methyltransferase biochemical genetics: Human lymphocyte enzyme. Biochem Genet 1981; 19: 1037-1053
20. Boudikova B, Szumlanski C, Maidak B, et al: Human liver catechol-O-methyl-transferase pharmacogenetics. Clin Pharmacol Ther 1990; 48:381-389
21. Cullen DJ, Nemeskal AR: Therapeutic intervention scoring system (TISS). In: Problems in Critical Care. Vol 3. Kirby RR, Taylor RW (Series Eds). Farmer JC (Ed). Philadelphia, JB Lipppincott, 1989, pp 545-562
22. Bioanalytical Systems (BAS) method for the determination of plasma catecholamines (LCEC Application Note #14)
23. Allen E, Myers C, Frank D, et al: Application of organic solvent extraction to the determination of catechol-O-methyl-transferase activity by high performance liquid chromatography in human mononuclear cells. J Chromatogr 1992; 578: 175-188
24. Lowry OH, Rosebrough NJ, Farr AL, et al: Protein measurement with the folin phenol reagent. J Biol Chem 1951; 193: 265-275
25. Blumer J, Ruggerie D, Weise KL, et al: Comparative pharmacokinetics of dopamine and dobutamine in children. Abstr. Crit Care Med 1989; 17:898
26. Tsuchiya T, Levy G: Relationship between dose and plateau levels of drugs eliminated by parallel first-order and capacity-limited kinetics. J Pharm Sci 1972; 61:541-544
27. Motulsky H, Insel P: Adrenergic receptors in man. Direct identification, physiologic regulation, and clinical implications. N Engl J Med 1981; 307:18-29
28. Besunder J, Reed M, Blumer J: Principles of drug biodisposition in the neonate. A critical evaluation of the pharmacokinetic-pharmacodynamic interface (part 1). Clin Pharmacol 1988; 14:189-216
29. Sumikawa K, Hirano H: Quantitative analysis of the contribution of hepatic, renal and portal circulation to the clearance of exogenous catecholamines. Res Commun Chem Pathol Pharmacol 1988; 60:337-346
30. Sumikawa K, Hayaski Y, Yamatodani A, et al: Contribution of the lungs to the clearance of exogenous dopamine in humans. Anesth Analg 1991; 72:622-626
31. Conney AH: Pharmacologic implications of microsomal enzyme induction. Pharm Rev 1967; 19:317-366
32. Conney AH, Davison C, Gastel R, et al: Adaptive increases in drug metabolizing enzymes induced by phenobarbital and other drugs. J Pharmacol Expt Ther 1960; 130:1-8
33. Weinshilboum R: Biochemical genetics of catecholamines in humans. Mayo Clin Proc 1983; 58:319-330
34. Floderus Y, Wetteberg L: The inheritance of human erythrocyte catechol-O-methyltransferase activity. Clin Genet 1991; 19:392-395
35. Scanlon P, Raymond F, Weinshilboum R: Catechol-O-methyltransferase: Thermolabile enzyme in erythrocytes of subjects homozygous for allele for low activity. Science 1979; 203:63-65
36. Spielman R, Weinshilboum R: Genetics of RBC cell COMT activity: Analysis of thermal stability and family data. Am J Med Genet 1981; 10:279-290