Characterization of the in vitro oxidative metabolites of the COX-2 selective inhibitor L-766,112

Bioorganic and Medicinal Chemistry Letters

Volumn 7, Issue 1, 1997, Pages 53-56

  Trimble, Laird A ^a   Chauret, Nathalie ^a   Silva, José M ^a   Nicoll Griffith, Deborah A ^a   Li, Chun Sing ^a   Yergey, James A ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

5 (4 METHYLSULFONYLPHENYL) 6 PHENYLIMIDAZO[2,1 B]THIAZOLE; CYCLOOXYGENASE 2 INHIBITOR; DRUG METABOLITE; NONSTEROID ANTIINFLAMMATORY AGENT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG IDENTIFICATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; LIVER METABOLISM; LIVER MICROSOME; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT; RHESUS MONKEY; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 0031032108     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(96)00581-1     Document Type: Article

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