-
1
-
-
0027478063
-
Modification of the megaprimer method of PCR mutagenesis: Improved amplification of the final product
-
Aiyar, A., Leis, J. 1993. Modification of the megaprimer method of PCR mutagenesis: Improved amplification of the final product. Biotechniques 14:366-369
-
(1993)
Biotechniques
, vol.14
, pp. 366-369
-
-
Aiyar, A.1
Leis, J.2
-
2
-
-
0026485739
-
Acetylcholine receptor channel structure probed in cysteine-substitution mutants
-
Akabas, M.H., Stauffer, D.A., Xu, M., Karlin, A. 1992. Acetylcholine receptor channel structure probed in cysteine-substitution mutants. Science 258:307-310
-
(1992)
Science
, vol.258
, pp. 307-310
-
-
Akabas, M.H.1
Stauffer, D.A.2
Xu, M.3
Karlin, A.4
-
3
-
-
0026755899
-
Molecular localization of an ion-binding site within the pore of mammalian sodium channels
-
Backx, P.H., Yue, D.T., Lawrence, J.H., Marban, E., Tomaselli, G.F. 1992. Molecular localization of an ion-binding site within the pore of mammalian sodium channels. Science 257:248-251
-
(1992)
Science
, vol.257
, pp. 248-251
-
-
Backx, P.H.1
Yue, D.T.2
Lawrence, J.H.3
Marban, E.4
Tomaselli, G.F.5
-
4
-
-
0019393846
-
Sodium current in single rat heart muscle cells
-
Brown, A.M., Lee, K.S., Powell, T. 1981. Sodium current in single rat heart muscle cells. J. Physiol. 318:479-500
-
(1981)
J. Physiol.
, vol.318
, pp. 479-500
-
-
Brown, A.M.1
Lee, K.S.2
Powell, T.3
-
5
-
-
0022450133
-
Amino-aromatic interactions in proteins
-
Burley, S.K., Petsko, G.A. 1986. Amino-aromatic interactions in proteins. FEBS Lett. 203:139-143
-
(1986)
FEBS Lett.
, vol.203
, pp. 139-143
-
-
Burley, S.K.1
Petsko, G.A.2
-
6
-
-
0025272768
-
How does vestibule surface charge affect ion conduction and toxin binding in a sodium channel?
-
Cai, M., Jordan, P.C. 1990. How does vestibule surface charge affect ion conduction and toxin binding in a sodium channel? Biophys. J. 57:883-891
-
(1990)
Biophys. J.
, vol.57
, pp. 883-891
-
-
Cai, M.1
Jordan, P.C.2
-
7
-
-
0026760836
-
Chimeric study of sodium channels from rat skeletal and cardiac muscle
-
Chen, L.-Q., Chahine, M, Kallen, R.G., Barchi, R.L., Horn, R. 1992. Chimeric study of sodium channels from rat skeletal and cardiac muscle. FEBS Lett. 309:253-257
-
(1992)
FEBS Lett.
, vol.309
, pp. 253-257
-
-
Chen, L.-Q.1
Chahine, M.2
Kallen, R.G.3
Barchi, R.L.4
Horn, R.5
-
8
-
-
8044232306
-
Cysteine mapping in the selectivity region of the sodium channel
-
Abstr.
-
Chen, S.-F., Hartmann, H.A., Kirsch, G.E. 1995. Cysteine mapping in the selectivity region of the sodium channel. Soc. Neurosci. Abstr. 21:1817 (Abstr.)
-
(1995)
Soc. Neurosci. Abstr.
, vol.21
, pp. 1817
-
-
Chen, S.-F.1
Hartmann, H.A.2
Kirsch, G.E.3
-
10
-
-
0030062943
-
Control of ion flux and selectivity by negatively charged residues in the outer mouth of rat sodium channels
-
Chiamvimonvat, N., Pérez-García, M.T., Tomaselli, G.F., Marban, E. 1996b. Control of ion flux and selectivity by negatively charged residues in the outer mouth of rat sodium channels. J. Physiol. 491:51-59
-
(1996)
J. Physiol.
, vol.491
, pp. 51-59
-
-
Chiamvimonvat, N.1
Pérez-García, M.T.2
Tomaselli, G.F.3
Marban, E.4
-
12
-
-
0022626737
-
Ion-channel entrances influence permeation. Net charge, size, shape, and binding considerations
-
Dani, J.A. 1986. Ion-channel entrances influence permeation. Net charge, size, shape, and binding considerations. Biophys. J. 49:607-618
-
(1986)
Biophys. J.
, vol.49
, pp. 607-618
-
-
Dani, J.A.1
-
13
-
-
85011599929
-
Potassium channels in mammalian brain: A molecular approach
-
T. Narahashi, editor. Academic Press, San Diego
-
Drewe, J.A., Hartmann, H.A., Kirsch, G.E. 1994. Potassium channels in mammalian brain: A molecular approach. In: Ion channels of excitable cells. T. Narahashi, editor. pp. 243-260. Academic Press, San Diego
-
(1994)
Ion Channels of Excitable Cells
, pp. 243-260
-
-
Drewe, J.A.1
Hartmann, H.A.2
Kirsch, G.E.3
-
14
-
-
0027322242
-
Modification of cardiac sodium channels by carboxyl reagents. Trimethyloxonium and water-soluble carbodiimide
-
Dudley, S.C., Baumgarten, C.M. 1993. Modification of cardiac sodium channels by carboxyl reagents. Trimethyloxonium and water-soluble carbodiimide. J. Gen. Physiol. 101:651-671
-
(1993)
J. Gen. Physiol.
, vol.101
, pp. 651-671
-
-
Dudley, S.C.1
Baumgarten, C.M.2
-
16
-
-
0026026676
-
Surface charges and ion channel function
-
Green, W.N., Andersen, O.S. 1991. Surface charges and ion channel function. Ann. Rev. Physiol. 53:341-359
-
(1991)
Ann. Rev. Physiol.
, vol.53
, pp. 341-359
-
-
Green, W.N.1
Andersen, O.S.2
-
17
-
-
0023221072
-
Batrachotoxin-modified sodium channels in planar lipid bilayers. Ion permeation and block
-
Green, W.N., Weiss, L.B., Andersen, O.S. 1987. Batrachotoxin-modified sodium channels in planar lipid bilayers. Ion permeation and block. J. Gen. Physiol. 89:841-872
-
(1987)
J. Gen. Physiol.
, vol.89
, pp. 841-872
-
-
Green, W.N.1
Weiss, L.B.2
Andersen, O.S.3
-
18
-
-
0025334586
-
Pursuing the structure and function of voltage-gated channels
-
Guy, H.R., Conti, F. 1990. Pursuing the structure and function of voltage-gated channels. Trends Neurosci. 13:201-206
-
(1990)
Trends Neurosci.
, vol.13
, pp. 201-206
-
-
Guy, H.R.1
Conti, F.2
-
19
-
-
0000882125
-
Molecular model of the action potential sodium channel
-
Guy, H.R., Seetharamulu, P. 1986. Molecular model of the action potential sodium channel. Proc. Natl. Acad. Sci. USA 83:508-512
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 508-512
-
-
Guy, H.R.1
Seetharamulu, P.2
-
21
-
-
0026698250
-
Molecular basis for pharmacological differences between brain and cardiac sodium channels
-
Heinemann, S.H., Terlau, H., Imoto, K. 1992a. Molecular basis for pharmacological differences between brain and cardiac sodium channels. Pfluegers Arch. 422:90-92
-
(1992)
Pfluegers Arch.
, vol.422
, pp. 90-92
-
-
Heinemann, S.H.1
Terlau, H.2
Imoto, K.3
-
22
-
-
0026517122
-
Calcium channel characteristics conferred on the sodium channel by single mutations
-
Heinemann, S.H., Terlau, H. Stühmer, W., Imoto, K., Numa, S. 1992b. Calcium channel characteristics conferred on the sodium channel by single mutations. Nature 356:441-443
-
(1992)
Nature
, vol.356
, pp. 441-443
-
-
Heinemann, S.H.1
Terlau, H.2
Stühmer, W.3
Imoto, K.4
Numa, S.5
-
23
-
-
0015166645
-
The permeability of the sodium channel to organic cations in myelinated nerve
-
Hille, B. 1971. The permeability of the sodium channel to organic cations in myelinated nerve. J. Gen. Physiol. 58:599-619
-
(1971)
J. Gen. Physiol.
, vol.58
, pp. 599-619
-
-
Hille, B.1
-
24
-
-
0015357133
-
The permeability of the sodium channel to metal cations in myelinated nerve
-
Hille, B. 1972. The permeability of the sodium channel to metal cations in myelinated nerve. J. Gen. Physiol. 59:637-658
-
(1972)
J. Gen. Physiol.
, vol.59
, pp. 637-658
-
-
Hille, B.1
-
25
-
-
0016782794
-
The receptor for tetrodotoxin and saxitoxin. A structural hypothesis
-
Hille, B. 1975. The receptor for tetrodotoxin and saxitoxin. A structural hypothesis. Biophys. J. 15:615-619
-
(1975)
Biophys. J.
, vol.15
, pp. 615-619
-
-
Hille, B.1
-
27
-
-
0016848139
-
Negative surface charge near sodium channels of nerve: Divalent ions, monovalent ions, and pH
-
Hille, B., Woodhull, A.M., Shapiro, B.I. 1975. Negative surface charge near sodium channels of nerve: Divalent ions, monovalent ions, and pH. Phil. Trans. R. Soc. Lond. 270:301-318
-
(1975)
Phil. Trans. R. Soc. Lond.
, vol.270
, pp. 301-318
-
-
Hille, B.1
Woodhull, A.M.2
Shapiro, B.I.3
-
28
-
-
0020452327
-
Actions of nortetrodotoxin on frog muscle and squid axon
-
Kao, C.Y. 1982. Actions of nortetrodotoxin on frog muscle and squid axon. Toxicon. 20:1043-1050
-
(1982)
Toxicon.
, vol.20
, pp. 1043-1050
-
-
Kao, C.Y.1
-
29
-
-
0028118783
-
Conductance mutations of the nicotinic acetylcholine receptor do not act by a simple electrostatic mechanism
-
Kienker, P., Tomaselli, G., Jurman, M., Yellen, G. 1994. Conductance mutations of the nicotinic acetylcholine receptor do not act by a simple electrostatic mechanism. Biophys. J. 66:325-334
-
(1994)
Biophys. J.
, vol.66
, pp. 325-334
-
-
Kienker, P.1
Tomaselli, G.2
Jurman, M.3
Yellen, G.4
-
30
-
-
0028035084
-
Differential effects of sulfhydryl reagents on saxitoxin and tetrodotoxin block of voltage-dependent Na channels
-
Kirsch, G.E., Alam, M., Hartmann, H.A. 1994. Differential effects of sulfhydryl reagents on saxitoxin and tetrodotoxin block of voltage-dependent Na channels. Biophys. J. 67:2305-2315
-
(1994)
Biophys. J.
, vol.67
, pp. 2305-2315
-
-
Kirsch, G.E.1
Alam, M.2
Hartmann, H.A.3
-
31
-
-
0027413853
-
Site-directed mutagenesis of the putative pore region of the rat HA sodium channel
-
Kontis, K.J., Goldin, A.L. 1993. Site-directed mutagenesis of the putative pore region of the rat HA sodium channel. Mol. Pharmacol. 43:635-644
-
(1993)
Mol. Pharmacol.
, vol.43
, pp. 635-644
-
-
Kontis, K.J.1
Goldin, A.L.2
-
32
-
-
0027436998
-
A mechanism for ion selectivity in potassium channels: Computational studies of cation-π interactions
-
Kumpf, R.A., Dougherty, D.A. 1993. A mechanism for ion selectivity in potassium channels: Computational studies of cation-π interactions. Science 261:1708-1710
-
(1993)
Science
, vol.261
, pp. 1708-1710
-
-
Kumpf, R.A.1
Dougherty, D.A.2
-
34
-
-
0022653969
-
Existence of distinct sodium channel messenger RNAs in rat brain
-
Noda, M., Ikeda, T., Kayano, T., Suzuki, H., Takeshima, H., Kurasaki, M., Takahashi, H., Numa, S. 1986. Existence of distinct sodium channel messenger RNAs in rat brain. Nature 320:188-192
-
(1986)
Nature
, vol.320
, pp. 188-192
-
-
Noda, M.1
Ikeda, T.2
Kayano, T.3
Suzuki, H.4
Takeshima, H.5
Kurasaki, M.6
Takahashi, H.7
Numa, S.8
-
35
-
-
0021123234
-
Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence
-
Noda, M., Shimizu, S., Tanabe, T., Takai, T., Kayano, T., Ikeda, T., Takahashi, H., Nakayama, H., Kanaoka, Y., Minamino, N., Kangawa, K., Matsuo, H., Raftery, M.A., Hirose, T., Inayama, S., Hayashida, H., Miyata, T., Numa, S. 1984. Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence. Nature 312:121-127
-
(1984)
Nature
, vol.312
, pp. 121-127
-
-
Noda, M.1
Shimizu, S.2
Tanabe, T.3
Takai, T.4
Kayano, T.5
Ikeda, T.6
Takahashi, H.7
Nakayama, H.8
Kanaoka, Y.9
Minamino, N.10
Kangawa, K.11
Matsuo, H.12
Raftery, M.A.13
Hirose, T.14
Inayama, S.15
Hayashida, H.16
Miyata, T.17
Numa, S.18
-
36
-
-
0024811092
-
A single point mutation confers tetrodotoxin and saxitoxin insensitivity on the sodium channel II
-
Noda, M., Suzuki, H., Numa, S., Stühmer, W. 1989. A single point mutation confers tetrodotoxin and saxitoxin insensitivity on the sodium channel II. FEBS Lett. 259:213-216
-
(1989)
FEBS Lett.
, vol.259
, pp. 213-216
-
-
Noda, M.1
Suzuki, H.2
Numa, S.3
Stühmer, W.4
-
38
-
-
0030051135
-
Structure of the sodium channel pore revealed by serial cysteine mutagenesis
-
Pérez-García, M.-T., Chiamvimonvat, N., Marban, E., Tomaselli, G.F. 1996. Structure of the sodium channel pore revealed by serial cysteine mutagenesis. Proc. Natl. Acad. Sci. USA 93:300-304
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 300-304
-
-
Pérez-García, M.-T.1
Chiamvimonvat, N.2
Marban, E.3
Tomaselli, G.F.4
-
39
-
-
0025737816
-
Single point mutations of the sodium channel drastically reduce the pore permeability without preventing its gating
-
Pusch, M., Noda, M., Stühmer, W., Numa, S., Conti, F. 1991. Single point mutations of the sodium channel drastically reduce the pore permeability without preventing its gating. Eur. Biophys. J. 20:127-133
-
(1991)
Eur. Biophys. J.
, vol.20
, pp. 127-133
-
-
Pusch, M.1
Noda, M.2
Stühmer, W.3
Numa, S.4
Conti, F.5
-
40
-
-
0026637366
-
A mutant of TTX-resistant cardiac sodium channels with TTX-sensitive properties
-
Satin, J., Kyle, J.W., Chen, M., Bell, P., Cribbs, L.L., Fozzard, H.A., Rogart, R.B. 1992. A mutant of TTX-resistant cardiac sodium channels with TTX-sensitive properties. Science 256:1202-1205
-
(1992)
Science
, vol.256
, pp. 1202-1205
-
-
Satin, J.1
Kyle, J.W.2
Chen, M.3
Bell, P.4
Cribbs, L.L.5
Fozzard, H.A.6
Rogart, R.B.7
-
41
-
-
0028108255
-
The saxitoxin/tetrodotoxin binding site on cloned rat brain IIa Na channels is in the transmembrane electric field
-
Satin, J., Limgeris, J.T., Kyle, J.W., Rogart, R.B., Fozzard, H.A. 1994. The saxitoxin/tetrodotoxin binding site on cloned rat brain IIa Na channels is in the transmembrane electric field. Biophys. J. 67: 1007-1014
-
(1994)
Biophys. J.
, vol.67
, pp. 1007-1014
-
-
Satin, J.1
Limgeris, J.T.2
Kyle, J.W.3
Rogart, R.B.4
Fozzard, H.A.5
-
42
-
-
0018881098
-
Chemical modification reduces the conductance of sodium channels in nerve
-
Sigworth, F.J., Spalding, B.C. 1980. Chemical modification reduces the conductance of sodium channels in nerve. Nature 238:293-295
-
(1980)
Nature
, vol.238
, pp. 293-295
-
-
Sigworth, F.J.1
Spalding, B.C.2
-
43
-
-
0018910573
-
Properties of toxin-resistant sodium channels produced by chemical modification in frog skeletal muscle
-
Spalding, B.C. 1980. Properties of toxin-resistant sodium channels produced by chemical modification in frog skeletal muscle. J. Physiol. 305:485-500
-
(1980)
J. Physiol.
, vol.305
, pp. 485-500
-
-
Spalding, B.C.1
-
44
-
-
0026072218
-
Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II
-
Terlau, H., Heinemann, S.H., Stühmer, W., Pusch, M., Conti, F., Imoto, K., Numa, S. 1991. Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II. FEBS Lett. 293:93-96
-
(1991)
FEBS Lett.
, vol.293
, pp. 93-96
-
-
Terlau, H.1
Heinemann, S.H.2
Stühmer, W.3
Pusch, M.4
Conti, F.5
Imoto, K.6
Numa, S.7
-
45
-
-
0024692740
-
Primary structure and functional expression of a mammalian skeletal muscle sodium channel
-
Trimmer, J.S., Cooperman, S.S., Tomiko, S.A., Zhou, J., Crean, S.M., Boyle, M.B., Kallen, R.G., Sheng, Z., Barchi, R.L., Sigworth, F.J., Goodman, R.H., Agnew, W.S., Mandel, G. 1989. Primary structure and functional expression of a mammalian skeletal muscle sodium channel. Neuron 3:33-49
-
(1989)
Neuron
, vol.3
, pp. 33-49
-
-
Trimmer, J.S.1
Cooperman, S.S.2
Tomiko, S.A.3
Zhou, J.4
Crean, S.M.5
Boyle, M.B.6
Kallen, R.G.7
Sheng, Z.8
Barchi, R.L.9
Sigworth, F.J.10
Goodman, R.H.11
Agnew, W.S.12
Mandel, G.13
-
46
-
-
0022599511
-
Trimethyloxonium modification of single batrachotoxin-activated sodium channels in planar bilayers
-
Worley III, J.F., French, R.J., Krueger, B.K. 1986. Trimethyloxonium modification of single batrachotoxin-activated sodium channels in planar bilayers. J. Gen. Physiol. 87:327-349
-
(1986)
J. Gen. Physiol.
, vol.87
, pp. 327-349
-
-
Worley III, J.F.1
French, R.J.2
Krueger, B.K.3
-
47
-
-
0026731650
-
Actions of Chiriquitoxin on frog skeletal muscle fibers and implications for the tetrodotoxin/saxitoxin receptor
-
Yang, L., Kao, C.Y. 1992. Actions of Chiriquitoxin on frog skeletal muscle fibers and implications for the tetrodotoxin/saxitoxin receptor. J. Gen. Physiol. 100:609-622
-
(1992)
J. Gen. Physiol.
, vol.100
, pp. 609-622
-
-
Yang, L.1
Kao, C.Y.2
|