Activation of metabotropic glutamate receptors increases endogenous protein kinase C substrate phosphorylation in adult hippocampal slices

Brain Research

Volumn 745, Issue 1-2, 1997, Pages 46-54

  Angenstein, Frank ^a   Hirschfelder, Monika ^a   Staak, Sabine ^a  

^a LEIBNIZ INSTITUTE FOR NEUROBIOLOGY   (Germany)

Author keywords

Hippocampal slice; In situ phosphorylation; MARCKS; Neurogranin; Phorbol ester; Protein kinase C translocation; Two dimensional gel electrophoresis

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; 3,5 DIHYDROXYPHENYLGLYCINE; GLUTAMATE RECEPTOR; METABOTROPIC RECEPTOR; PHORBOL 13 ACETATE 12 MYRISTATE; PHORBOL ESTER; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR; QUISQUALIC ACID;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; HIPPOCAMPUS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT;

ANIMALS; AUTORADIOGRAPHY; BIOTRANSFORMATION; CYCLOLEUCINE; EXCITATORY AMINO ACID AGONISTS; HIPPOCAMPUS; ISOENZYMES; MALE; N-METHYLASPARTATE; NEUROPROTECTIVE AGENTS; PHOSPHORYLATION; PROTEIN KINASE C; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, MUSCARINIC; SUBCELLULAR FRACTIONS; TETRADECANOYLPHORBOL ACETATE;

EID: 0031031612     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)01129-8     Document Type: Article

References (32)

1. Baudier, J., Bronner, C., Kligman, D. and Cole, R.D., Protein kinase C substrates from bovine brain, J. Biol. Chem., 264 (1989) 1824-1828.
2. Bazzi, M.D. and Nelsestuen, G.L., Properties of membrane inserted protein kinase C, Biochemistry, 27 (1988) 7589-7593.
3. Bell, R.M., Protein kinase C activation by diacylglycerol second messengers, Cell, 45 (1986) 631-632.
4. Bell, R.M. and Bruns, D.J., Lipid activation of protein kinase C, J. Biol. Chem., 266 (1991) 4661-4664.
5. Boss, V., Desai, M.A., Smith, T.S. and Conn, P.J., trans-ACPD-induced phosphoinositide hydrolysis and modulation of hippocampal pyramidal cell excitability do not undergo parallel developmental regulation, Brain Res., 594 (1992) 181-188.
6. Bradford, M.M., A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding, Anal. Biochem., 72 (1976) 248-254.
7. Chakravarthy, B.R., Whitfield, J.F. and Durkin, J.P., Inactive membrane protein kinase Cs: a possible target for receptor signalling, Biochem. J., 304 (1994) 809-816.
8. Coffey, E.T., Herrero, I., Sihra, T.S., Sánchez-Prieto, J. and Nicholls, D.G., Glutamate exocytosis and MARCKS phosphorylation are enhanced by a metabotropic glutamate receptor coupled to a protein kinase C synergistically activated by diacylglycerol and arachidonic acid, J. Neurochem., 63 (1994) 1303-1310.
9. Fujise, A., Mizuno, K., Ueda, Y., Osada, S., Hirai, S., Takayanagi, A., Shimuzi, N., Owada, M.K., Nakajima, H. and Ohno, S., Specificity of the high affinity interaction of protein kinase C with a physiological substrate, myristyolated alanine-rich protein kinase C substrate, J. Biol. Chem., 269 (1994) 31642-31648.
10. Golapakrishna, R., Barsky, S.H., Thomas, T.P. and Anderson, W.B., Factors influencing chelator-stable, detergent-extractable, phorboldiester induced membrane association of protein kinase C, J. Biol. Chem., 261 (1989) 16438-16445.
11. Hannun, Y.A., Loomis, C.R. and Bell, R.M., Activation of protein kinase C by triton X-100 mixed micelles containing diacylglycerol and phosphatidylserine, J. Biol. Chem., 260 (1985) 10039-10043.
12. Hochstrasser, D.F., Harrington, M.G., Hochstrasser, A.-C., Miller, M.J. and Merril, C.R., Methods for increasing the resolution of two-dimensional protein electrophoresis, Anal. Biochem., 173 (1988) 424-435.
13. Huang, F.L., Yoshida, Y., Nakabayashi, H., Young, W.S. and Huang, K.P., Immunocytochemical localization of protein kinase C isoenzyme in rat brain, J. Neurosci., 8 (1988) 4734-4744.
14. Kikkawa, U., Takai, Y., Minakuchi, R., Inohara, S.I. and Nishizuka, Y., Calcium-activated, phopholipid-dependent protein kinase from rat brain, J. Biol. Chem., 257 (1982) 13341-13341.
15. Klann, E., Chen, S.-J. and Sweatt, J.D., Increased phosphorylation of a 17-kDa protein kinase C substrate (P 17) in long-term potentiation., J. Neurochem., 58 (1992) 1576-1579.
16. Kraft, A.S. and Anderson, W.B., Phorbol esters increase the amount of calcium, phospholipid dependent protein kinase associated with plasma membrane, Nature, 301 (1983) 621-623.
17. Nishizuka, Y., Intracellular signalling by hydrolysis of phospholipids and activation of protein kinase C, Science, 258 (1992) 607-614.
18. Otani, S. and Ben-Ari, Y., Biochemical correlates of long-term potentiation in hippocampal synapses, Int. Rev. Neurobiol., 35 (1993) 1-44.
19. Otani, S., Ben-Ari, Y. and Roisin-Lallemand, M.P., Metabotropic receptor stimulation coupled to weak tetanus leads to long-term potentiation and a rapid elevation of cytosolic protein kinase C activity, Brain Res., 613 (1993) 1-9.
20. Reymann, K.G. and Staak, S. In P.L. Canonico, U. Scapagnini, F. Pamparana and A. Routtenberg (Eds.), Protein Kinase C in the CNS Focus on Neuronal Plasticity: Proceedings, Masson, Milano/Paris/Barcelona, 1994, pp. 31-56.
21. Riedel, G., Casabona, G. and Reymann, K.G., Inhibition of long-term potentiation in the dentate gyrus of freely moving rats by the metabotropic glutamate receptor antagonist MCPG, J. Neurosci., 15 (1995) 87-98.
22. Sacktor, T.C., Osten, P., Valsamis, H., Jiang, X. and Sublette, E., Persistent activation of the ζ isoform of protein kinase C in the maintenance of long-term potentiation, Proc. Natl. Acad. Sci. USA, 90 (1993) 8342-8346.
23. Sallés, J., A., W. and Fain, J.N., Modulation of the phospholipase C activity in rat brain cortical membranes by simultaneous activation of distinct monoaminergic and cholinergic muscarinic receptors, Mol. Brain Res., 20 (1993) 111-117.
24. Scholz, W.K., An ibotenate-selective metabotropic glutamate receptor mediates protein phosphorylation in cultured hippocampal pyramidal neurons, J. Neurochem., 62 (1994) 1764-1772.
25. Scholz, W.K. and Palfrey, H.C., Glutamate-stimulated protein-phosphorylation in cultured hippocampal pyramidal neurons, J. Neurosci., 11 (1991) 2422-2432.
26. Shaffer, L.M., Man, Y.-F. and Dokas, L.A., Phorbol ester- and glutamate-sensitive phosphorylation of hippocampal membrane proteins from adult and neonatal rats, Dev. Brain Res., 73 (1993) 133-139.
27. Staak, S., Behnisch, T. and Angenstein, F., Hippocampal long-term potentiation: transient increase but no persistent translocation of protein kinase C isoenzymes α and β, Brain Res., 682 (1995) 55-62.
28. 2+-independent form of kinase C in long-term potentiation, Biochem. Biophys. Res. Commun., 189 (1992) 1515-1520.
29. Tan, S.-E., Wenthold, R.J. and Soderling, T.R., Phosphorylation of AMPA-Type glutamate receptors by calcium/ calmodulin-dependent protein kinase II and protein kinase C in cultured hippocampal neurons, J. Neurosci., 14 (1994) 1123-1129.
30. Tobwin, H., Staehelin, T. and Gorden, J., Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose: procedure and some applications, Proc. Natl. Acad. Sci. USA, 76 (1979) 4350-4354.
31. Trilivas, I., McDonough, P.M. and Brown, J.H., Dissociation of protein kinase C redistribution from the phosphorylation of its substrates, J. Biol. Chem., 266 (1991) 8431-8438.
32. Zatz, M., Translocation of protein kinase C in rat hippocampal slices, Brain Res., 385 (1986) 174-178.