메뉴 건너뛰기




Volumn 272, Issue 1 35-1, 1997, Pages

Use of labeling pattern of liver glutamate to calculate rates of citric acid cycle and gluconeogenesis

Author keywords

chemical biopsy; lactate; pyruvate metabolism; stable isotope

Indexed keywords

CARBON 13; GLUTAMIC ACID; LACTIC ACID; LIVER ENZYME; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); PYRUVATE DEHYDROGENASE; PYRUVATE KINASE; PYRUVIC ACID;

EID: 0031031340     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1997.272.1.e51     Document Type: Article
Times cited : (28)

References (30)
  • 2
    • 0027337194 scopus 로고
    • 13C labeling pattern of glutamate by gas chromatography-mass spectrometry
    • 13C labeling pattern of glutamate by gas chromatography-mass spectrometry. Anal. Biochem. 212: 532-536, 1993.
    • (1993) Anal. Biochem. , vol.212 , pp. 532-536
    • Beylot, M.1    David, F.2    Brunengraber, H.3
  • 5
    • 0016693944 scopus 로고
    • The effects of inhibition of gluconeogenesis on ketogenesis in starved and diabetic rats
    • Blackshear, P. J., P. A. H. Holloway, and K. G. M. M. Alberti. The effects of inhibition of gluconeogenesis on ketogenesis in starved and diabetic rats. Biochem. J. 148: 353-362, 1975.
    • (1975) Biochem. J. , vol.148 , pp. 353-362
    • Blackshear, P.J.1    Holloway, P.A.H.2    Alberti, K.G.M.M.3
  • 6
    • 0018717177 scopus 로고
    • Modulation of the phosphorylation state of rat liver pyruvate kinase by allosteric effectors and insulin
    • Claus, T. H., H. R. El-Maghrabi, and S. J. Pilkis. Modulation of the phosphorylation state of rat liver pyruvate kinase by allosteric effectors and insulin. J. Biol. Chem. 254: 7855-7864, 1979.
    • (1979) J. Biol. Chem. , vol.254 , pp. 7855-7864
    • Claus, T.H.1    El-Maghrabi, H.R.2    Pilkis, S.J.3
  • 7
    • 0023605591 scopus 로고
    • Determination of Krebs cycle carbon exchange in vivo and its use to estimate the individual contributions of gluconeogenesis and glycogenolysis to overall glucose output in man
    • Consoli, A., J. Kennedy, J. Miles, and J. E. Gerich. Determination of Krebs cycle carbon exchange in vivo and its use to estimate the individual contributions of gluconeogenesis and glycogenolysis to overall glucose output in man. J. Clin. Invest. 80: 1303-1310, 1987.
    • (1987) J. Clin. Invest. , vol.80 , pp. 1303-1310
    • Consoli, A.1    Kennedy, J.2    Miles, J.3    Gerich, J.E.4
  • 9
    • 0014198445 scopus 로고
    • Control of gluconeogenesis in liver. I. General features of gluconeogenesis in the perfused livers or rats
    • Exton, J. H., and C. R. Park. Control of gluconeogenesis in liver. I. General features of gluconeogenesis in the perfused livers or rats. J. Biol. Chem. 242: 2622-2636, 1967.
    • (1967) J. Biol. Chem. , vol.242 , pp. 2622-2636
    • Exton, J.H.1    Park, C.R.2
  • 10
    • 0020063476 scopus 로고
    • 12C atoms in the pathway of gluconeogenesis in vivo
    • 12C atoms in the pathway of gluconeogenesis in vivo. Federation Proc. 41: 104-109, 1985.
    • (1985) Federation Proc. , vol.41 , pp. 104-109
    • Hetenyi Jr., G.1
  • 11
    • 0015523324 scopus 로고
    • The conjugation of phenylacetic acid in man, sub-human primates and some non-primate species
    • James, M. O., R. L. Smith, R. T. Williams, and M. Reidenberg. The conjugation of phenylacetic acid in man, sub-human primates and some non-primate species. Proc. R. Soc. Lond. 182: 25-35, 1957.
    • (1957) Proc. R. Soc. Lond. , vol.182 , pp. 25-35
    • James, M.O.1    Smith, R.L.2    Williams, R.T.3    Reidenberg, M.4
  • 12
    • 0022048405 scopus 로고
    • 14C labeled substrates
    • Regulatory Integrative Comp. Physiol. 17
    • 14C labeled substrates. Am. J. Physiol. 248 (Regulatory Integrative Comp. Physiol. 17): R391-R399, 1985.
    • (1985) Am. J. Physiol. , vol.248
    • Katz, J.1
  • 13
    • 0022454148 scopus 로고
    • Gluconeogenesis from labeled carbon: Estimating isotope dilution
    • Endocrinol. Metab. 13
    • Kelleher, J. K. Gluconeogenesis from labeled carbon: estimating isotope dilution. Am. J. Physiol. 250 (Endocrinol. Metab. 13): E296-E305, 1986.
    • (1986) Am. J. Physiol. , vol.250
    • Kelleher, J.K.1
  • 14
    • 0013956638 scopus 로고
    • The fate of isotopic carbon in kidney cortex synthesizing glucose from lactate
    • Krebs, H. A., R. Hems, M. J. Weidemann, and R. N. Speake. The fate of isotopic carbon in kidney cortex synthesizing glucose from lactate. Biochem. J. 101: 242-249, 1966.
    • (1966) Biochem. J. , vol.101 , pp. 242-249
    • Krebs, H.A.1    Hems, R.2    Weidemann, M.J.3    Speake, R.N.4
  • 15
    • 0029044616 scopus 로고
    • Estimates of Krebs cycle activity and contributions of gluconeogenesis to hepatic glucose production in fasting healthy subjects and IDDM patients
    • Landau, B. R., V. Chandramouli, W. C. Schumann, K. Ekberg, K. Kumaran, S. C. Kalhan, and J. Wahren. Estimates of Krebs cycle activity and contributions of gluconeogenesis to hepatic glucose production in fasting healthy subjects and IDDM patients. Diabetologia 38: 831-838, 1995.
    • (1995) Diabetologia , vol.38 , pp. 831-838
    • Landau, B.R.1    Chandramouli, V.2    Schumann, W.C.3    Ekberg, K.4    Kumaran, K.5    Kalhan, S.C.6    Wahren, J.7
  • 16
    • 0029025630 scopus 로고
    • Lactate and pyruvate isotopic enrichments in plasma and tissues of postabsorptive and starved rats
    • Endocrinol. Metab. 31
    • Large, V., M. Soloviev, H. Brunengraber, and M. Beylot. Lactate and pyruvate isotopic enrichments in plasma and tissues of postabsorptive and starved rats. Am. J. Physiol. 268 (Endocrinol. Metab. 31): E880-E888, 1995.
    • (1995) Am. J. Physiol. , vol.268
    • Large, V.1    Soloviev, M.2    Brunengraber, H.3    Beylot, M.4
  • 18
    • 0344162984 scopus 로고
    • Regulation of liver pyruvate kinase and the phosphoenolpyruvate crossroad
    • Llorente, P., R. Marco, and A. Sols. Regulation of liver pyruvate kinase and the phosphoenolpyruvate crossroad. Eur. J. Biochem. 68: 497-506, 1976.
    • (1976) Eur. J. Biochem. , vol.68 , pp. 497-506
    • Llorente, P.1    Marco, R.2    Sols, A.3
  • 20
    • 0000904694 scopus 로고
    • Synthesis of phenylacetylglutamine by human tissues
    • Moldave, K., and A. Meister. Synthesis of phenylacetylglutamine by human tissues. J. Biol. Chem. 229: 463-476, 1957.
    • (1957) J. Biol. Chem. , vol.229 , pp. 463-476
    • Moldave, K.1    Meister, A.2
  • 21
    • 0020328983 scopus 로고
    • Regulation by glucagon of hepatic pyruvate kinase, 6-phospho-fructokinase and fructose 2-6 biphosphatase
    • Pilkis, S. J., M. R. El-Maghrabi, M. McGrave, J. Pilkis, and T. H. Claus. Regulation by glucagon of hepatic pyruvate kinase, 6-phospho-fructokinase and fructose 2-6 biphosphatase. Federation Proc. 41: 2623-2628, 1982.
    • (1982) Federation Proc. , vol.41 , pp. 2623-2628
    • Pilkis, S.J.1    El-Maghrabi, M.R.2    McGrave, M.3    Pilkis, J.4    Claus, T.H.5
  • 24
    • 0021763961 scopus 로고
    • Use of t-butyldimethylsilylation in the GC-MS analysis of physiological compounds found in plasma using electron impact ionization
    • Schwenck, W. K., P. J. Berg, B. Beaufrère, J. M. Miles, and M. W. Raymond. Use of t-butyldimethylsilylation in the GC-MS analysis of physiological compounds found in plasma using electron impact ionization. Anal. Biochem. 141: 101-109, 1984.
    • (1984) Anal. Biochem. , vol.141 , pp. 101-109
    • Schwenck, W.K.1    Berg, P.J.2    Beaufrère, B.3    Miles, J.M.4    Raymond, M.W.5
  • 25
    • 0017347216 scopus 로고
    • Effect of dichloroacetate on gluconeogenesis in isolated rat hepatocytes
    • Stacpoole, P. W. Effect of dichloroacetate on gluconeogenesis in isolated rat hepatocytes. Metab. Clin. Exp. 26: 107-115, 1977.
    • (1977) Metab. Clin. Exp. , vol.26 , pp. 107-115
    • Stacpoole, P.W.1
  • 26
    • 0000815130 scopus 로고
    • Incorporation of acetate carbon into glucose by liver slices from normal and alloxan diabetic rats
    • Strisower, E. G., G. D. Kolher, and I. L. Chaikoff. Incorporation of acetate carbon into glucose by liver slices from normal and alloxan diabetic rats. J. Biol. Chem. 188: 115-126, 1952.
    • (1952) J. Biol. Chem. , vol.188 , pp. 115-126
    • Strisower, E.G.1    Kolher, G.D.2    Chaikoff, I.L.3
  • 27
    • 0016285850 scopus 로고
    • Mechanism of activation of pyruvate dehydrogenase by dichloroacetate and other halogenated carboxylic acids
    • Whitehouse, S., R. M. Cooper, and P. J. Randle. Mechanism of activation of pyruvate dehydrogenase by dichloroacetate and other halogenated carboxylic acids. Biochem. J. 141: 761-774, 1974.
    • (1974) Biochem. J. , vol.141 , pp. 761-774
    • Whitehouse, S.1    Cooper, R.M.2    Randle, P.J.3
  • 28
    • 0020465703 scopus 로고
    • Estimation of branched chain α-ketoacids in blood by gas chromatography
    • Woolf, L. I., C. Hasinoff, and A. Perry. Estimation of branched chain α-ketoacids in blood by gas chromatography. J. Chromatogr. 231: 236- 245, 1982.
    • (1982) J. Chromatogr. , vol.231 , pp. 236-245
    • Woolf, L.I.1    Hasinoff, C.2    Perry, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.