Glial cell line-derived neurotrophic factor (GDNF) is a neurotrophic factor for sensory neurons: Comparison with the effects of the neurotrophins

Journal of Neurobiology

Volumn 32, Issue 1, 1997, Pages 22-32

  Matheson, Christine R ^a   Carnahan, Josette ^a   Urich, Janal L ^a   Bocangel, Dora ^a   Zhang, T J ^a   Yan, Qiao ^a  

^a AMGEN INC   (United States)

Author keywords

axotomy; DRG; GDNF; neuronal survival; neurotrophins; retrograde transport

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; NERVE GROWTH FACTOR;

ARTICLE; GLIA CELL; HUMAN; HUMAN CELL; NERVE FIBER TRANSECTION; NERVE GROWTH; NEUROTROPISM; PRIORITY JOURNAL; SCIATIC NERVE; SENSORY NERVE CELL; SPINAL GANGLION;

ANIMALS; ANIMALS, NEWBORN; AUTORADIOGRAPHY; AXONAL TRANSPORT; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL COUNT; CELL DEATH; CELL SIZE; CELL SURVIVAL; CELLS, CULTURED; CHICKENS; ESCHERICHIA COLI; GANGLIA, SPINAL; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; HUMANS; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEURONS, AFFERENT; NEUROPROTECTIVE AGENTS; NEUROTROPHIN 3; RADIOLIGAND ASSAY; RATS; SCIATIC NERVE;

EID: 0031031298     PISSN: 00223034     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4695(199701)32:1<22::AID-NEU3>3.0.CO;2-G     Document Type: Article

References (41)

1. ABERCROMBIE, M. (1946). Estimation of nuclear populations from microtome sections. Anat. Rec. 94:239-247.
2. BUCHMAN, V. L. and DAVIES, A. M. (1993). Different neurotrophins are expressed and act in a developmental sequence to promote the survival of embryonic sensory neurons. Development 118:989-1001.
3. BUJ-BELLO, A., BUCHMAN, V. L., HORTON, A., ROSENTHAL, A., and DAVIES, A. M. (1995). GDNF is an age specific factor for sensory and autonomic neurons. Neuron 15:821-828.
4. CROWLEY, C., SPENCER, S. D., NISHIMURA, M. C., CHEN, K. S., PITTS-MEEK, S., ARMANINI, M. P., LING, L. H., MCMAHON, S. B., SHELTON, D. L., LEVINSON, A. D., and PHILLIPS, H. S. (1994). Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons. Cell 76:1001-1011.
5. DAVIES, A. M., HORTON, A., BURTON, L. E., SCHMELZER, C., VANDLEN, R., and ROSENTHAL, A. (1994). Neurotrophin-4/5 is a mammalian-specific survival factor for distinct population of sensory neurons. J. Neurosci. 13:4961-4967.
6. DISTEFANo, P. S., FRIEDMAN, B., RADZIEJEWSKI, C., ALEXANDER, C., BOLAND, P., SCHICK, C. M., LINDSAY, R. M., and WEIGAND, S. J. (1992). The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons. Neuron 8:983-993.
7. ERNFORS, P. and PERSSON, H. (1991). Developmentally regulated expression of HDNF/NT-3 mRNA in rat spinal cord motor neurons and expression of BDNF in embryonic dorsal root ganglion. Eur. J. Neurosci. 3:953-961.
8. ERNFORS, P., LEE, K. F., KUCERA, J., and JAENISCH, R. (1994). Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents. Cell 77:503-512.
9. ERNFORS, P., LEE, K.-F., and JAENISCH, R. (1994). Mice lacking brain-derived neurotrophic factor develop with sensory deficits. Nature 368:147-150.
10. ERIKSSON, N. P., LINDSAY, R. M., and ALDSKOGIUS, H. (1994). BDNF and NT-3 rescue sensory but not motoneurons following axotomy in the neonate. Neuroreport 5:1445-1448.
11. FARINAS, I., JONES, K. R., BACKUS, C., WANG, X.-Y., and REICHARDT, L. F. (1994). Severe sensory and sympathetic deficits in mice lacking neurotrophin-3. Nature 369:658-661.
12. FRIEDMAN, L. and MYTILINEOU, C. (1987). The toxicity MPTP to dopamine neurons in culture is reduced at high concentrations. Neurosci. Lett. 79:65-72.
13. HENDERSON, C. E., PHILLIPS, H. S., POLLOCK, R. A., DAVIES, A. M., LEMEULLE, C., ARMANINI, M., SIMPSON, L. C., MOFFAT, B., VANDLEN, R. A., KOLLIATSOS, V. E., and ROSENTHAL, A. (1994). GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle. Nature 266:1062-1064.
14. HENDRY, I. A., STACH, R. A., and HERRUP, K. (1974). Characteristics of the retrograde transport system for nerve growth factor in the sympathetic nervous system. Brain Res. 82:117-128.
15. HIMES, T. and TESSLER, A. (1989). Death of some dorsal root ganglion neurons and plasticity of others following sciatic nerve section in adult and neonatal. J. Comp. Neural. 284:215-230.
16. HOHN, A., LEIBROCK, J., BAILEY, K., and BARDE, Y.-A. (1990). Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family. Nature 344:339-341.
17. HORY-LEE, F., RUSSELL, M., LINDSAY, R. M., and FRANK, E. (1993). Neurotrophin-3 supports the survival of developing muscle sensory neurons in culture. Proc. Natl Acad. Sci. USA 90:2613-2617.
18. 125NGF. Brain Res. 150:319-331.
19. KLEIN, R., LAMBALLE, F., BRYANT, S., and BARBACID, M. (1992). The trkB tyrosine protein kinase is a receptor for neurotrophin-4. Neuron 8:947-956.
20. LIN, L.-F. H., DOHERTY, D. H., LILE, J. D., BEKTESH, S., and COLLINS, F. (1993). GDNF: a glial cell-line derived neurotrophic factor for midbrain dopaminergic neurons. Nature 260:1130-1132.
21. LINDSAY, R. M., THOENEN, H., and BARDE, Y.-A. (1985). Placode and neural crest-derived sensory neurons are responsive at early developmental stages to brain-derived neurotrophic factor. Dev. Biol. 112:319-328.
22. MCMAHON, S. B., ARMANINI, M. P., LING, L. H., and PHILLIPS, H. S. (1994). Expression and coexpression of trk receptors in subpopulations of adult primary sensory neurons projecting to identified peripheral targets. Neuron 12:1161-1171.
23. MAISONPIERRE, P. C., BELLUSCIO, L., SQUINTO, S., IP, N. Y., FURTH, M. E., LINDAY, R. M., and YANCOPOULOS, G. (1990). Neurotrophin-3: a neurotrophic factor related to NGF and BDNF. Science 247:1446-1451.
24. MARCHALONIS, J. J. (1969). An enzyme method for the trace iodination of immunoglobulins and other proteins. Biochem. J. 113:229-305.
25. MEMBERG, S. P. and HALL, A. K. (1995). Proliferation, differentiation, and survival of rat sensory neuron precursers in vitro require specific trophic factors. Mol. Cell. Neurosci. 6:323-335.
26. MU, X., SILOS-SANTIAGO, I., CARROLL, S. L., and SNIDER, W. D. (1993). Neurotrophin receptor genes are expressed in distinct patterns in developing dorsal root ganglia. J. Neurosci. 13:4029-4041.
27. SCHECTERSON, L. C. and BOTHWELL, M. (1992). Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons. Neuron 9:449-463.
28. SMEYNE, R. J., KLEIN, R., SCHNAPP, A., LONG, L. K., BRYANT S., LEWIN, A., LIRA, S. A., and BARBACID, M. (1994). Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene. Nature 368:246-249.
29. SNIDER, W. D. and JOHNSON, E. M., JR. (1989). Neurotrophic molecules. Ann. Neural. 26:489-506.
30. SNIDER, W. D., ELLIOTT, J. L., and YAN, Q. (1992). Axotomy-induced neuronal death during development. J. Neurosci. 23:1231-1246.
31. SNIDER, W. D. and WRIGHT, D. E. (1996). Neurotrophins cause a new sensation. Neuron 16:229-232.
32. STROMBERG, I., BJORKLUND, L., JOHANSSON, M., TOMAC, A., COLLINS, F., OLSON, L., HOFFER, B., and HUMPEL, C. (1993). Glial cell line-derived neurotrophic factor is expressed in the developing but not adult striatum and stimulates developing dopamine neurons in vivo. Exp. Neural. 124:401-412.
33. SPINA, M. B., SQUINTO, S. P., MILLER, J., LINDSAY, R. M., and HYMAN, C. (1992). BDNF protects dopamine neurons against 6-OHDA and MPP+ toxicity: involvement of the glutathione system. J. Neurochem. 59:99-106.
34. THOENEN, H. and BARDE, Y.-A. (1980). Physiology of nerve growth factor. Physiol. Rev. 60:1284-1335.
35. TOMAC, A., LINDQVIST, E., LIN, L.-H. F., ORGON, S. O., YOUNG, D., HOFFER, B. J., and OLSON, L. (1995). Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo. Nature 373:335-339.
36. TRUPP, M., RYDEN, M., JORNVALL, H., FUNAKOSHI, H., TIMMUSK, T., ARENAS, E., and IBANEZ, C. F. (1995). Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons. J. Cell Biol. 130:137-148.
37. OPPENHEIM, R. W., HOUONOU, L., JOHNSON, J. E., LIN, L.-F. H., LI, L., LE, A. C., NEWSOME, A. L., PREVETTE, D. M., and WANG, S. (1995). Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF. Nature 373:344-346.
38. YAN, Q., ELLIOTT, J. L., and SNIDER, W. D. (1992). Brain-derived neurotrophic factor rescues spinal motoneurons from axotomy induced cell death. Nature 360:753-755.
39. YAN, Q., ELLIOTT, J. L., MATHESON, C., SUN, J., ZHANG, L., MU, X., REX, K. L., and SNIDER, W. (1993). Influences of neurotrophins on mammalian motoneurons in vivo. J. Neurobiol. 24:1555-1577.
40. YAN, Q., MATHESON, C., and LOPEZ, O. T. (1995). In vivo neurotrophic effects of GDNF on neonatal and adult facial motoneurons. Nature 373:341-344.
41. YIP, H. K., RICH, K. M., LAMPE, P. A., and JOHNSON, E. M., JR. (1984). The effects of nerve growth factor and its antiserum on the postnatal development and survival after injury of sensory neurons in rat dorsal root ganglia. J. Neurosci. 4:2986-2992.