Suppression of experimental autoimmune encephalomyelitis (EAE) by intraperitoneal administration of soluble myelin antigens in Wistar rats

Journal of Neuroimmunology

Volumn 72, Issue 1, 1997, Pages 3-10

  Rivero, V E ^a   Maccioni, M ^a   Bucher, A E ^a   Roth, G A ^a   Riera, C M ^a  

^a UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

Author keywords

autoimmunity; experimental autoimmune encephalomyelitis; immunoglobulin isotypes; myelin basic protein; suppression

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MYELIN; MYELIN BASIC PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOIMMUNITY; CELL PROLIFERATION; ENCEPHALOMYELITIS; FEMALE; HISTOLOGY; HUMORAL IMMUNITY; IMMUNIZATION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MONONUCLEAR CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SPLEEN CELL;

ANIMALS; ANTIBODY FORMATION; AUTOIMMUNITY; BRAIN; CATTLE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNIZATION; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INJECTIONS, INTRAPERITONEAL; MALE; MYELIN BASIC PROTEINS; RATS; RATS, WISTAR; SOLUBILITY; SPINAL CORD; SPLEEN;

EID: 0031031186     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(96)00117-8     Document Type: Article

References (35)

1. Aharoni, R., Teitelbaum, D., Arnon, R. and Puri, J. (1991) Immunomodulation of experimental allergic encephalomyelitis by antibodies to the antigen-Ia complex. Nature (London) 351, 147-150.
2. Amitabh, G., Wiers, B., Liu, A., Rothbard, J. and Fathman, C.G. (1992) Amelioration of autoimmune encephalomyelitis by myelin basic protein synthetic peptide-induced anergy. Science 258, 1491-1494.
3. Autilio, L.A., Norton, W.T. and Terry, R.D. (1964) The preparation and some properties of purified myelin from the central nervous system. J. Neurochem. 11, 17-27.
4. Bitar, D. and Whitacre, C.C. (1988) Suppression of experimental autoimmune encephalomyelitis by the oral administration of myelin basic protein. Cell. Immunol. 112, 364-370.
5. Correa, S.G. and Riera, C.M. (1991) Adjuvant effect of liposomes in the autoimmune response to rat male accessory glands. Immunol. Lett. 28, 39-46.
6. Ferro, M.E., Galmarini, M. and Riera, C.M. (1985) Antigen-induced inhibition to rat male accessory glands. Am. J. Reprod. Immunol. Microbiol. 9, 73-76.
7. Ferro, M.E., Yranzo-Volonté, N. and Riera, C.M. (1987) Adoptive transfer of suppression of autoimmune response to rat male accessory glands. Characterization of the suppressor cells. Immunol. Lett. 16, 125-132.
8. Ferro, M.E., Romero-Piffiguer, M. and Riera, C.M. (1990) Antigen-induced inhibition to rat male accessory glands: Distinct role of I-A and I-E positive peritoneal cells. Eur. J. Immunol. 20, 1007-1012.
9. Galmarini, M., Serra, H., Pistoresi-Palencia, C., Vottero-Cima, E. and Riera, C.M. (1986) Production of rat male accessory gland lesion by transfer of spleen mononuclear cells. Cell. Mol. Biol. 32, 293-301.
10. Galmarini, M., Ferro, M.E. and Riera, C.M. (1988) Delayed hypersensitivity and lesions following isoimmunization with modified rat male accessory glands: Kinetics of induction. J. Reprod. Immunol. 13, 147-157.
11. Heber-Katz, E. and Acha Orbea, H. (1989) The V-region disease hypothesis: Evidence from autoimmune encephalomyelitis. Immunol. Today 10, 164-169.
12. Higgins, P.J. and Weiner, H.L. (1988) Suppression of experimental allergic encephalomyelitis by oral administration of myelin basic protein. J. Immunol. 140, 440-445.
13. Karpus, W.J. and Swanborg, R.H. (1991) Protection against experimental autoimmune encephalomyelitis requires both CD4+ T suppressor cells and myelin basic protein-primed B cells. J. Neuroimmunol. 33, 173-177.
14. Kennedy, M.K., Dal Canto, M.C., Trotter, J.L. and Miller, S.D. (1988) Specific immune regulation of chronic-relapsing experimental allergic encephalomyelitis in mice. J. Immunol. 141, 2986-2993.
15. Kennedy, M.K., Tan, L.J., Dal Canto, M.C., Tuohy, V.K., Lu, Z., Trotter, J.L. and Miller, S.D. (1990) Inhibition of murine relapsing experimental allergic encephalomyelitis by immune tolerance to proteolipid protein and its encephalitogenic peptides. J. Immunol. 144, 909-915.
16. Laemmli, U.K. (1970) Cleveage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227, 680-685.
17. Miller, S.D. and Karpus, W. (1994) The immunopathogenesis and regulation of T-cell-mediated demyelinating diseases. Immunol. Today 15, 356-361.
18. Miller, A., Lider, O., Abramsky, O. and Weiner, H.L. (1994) Orally administered myelin basic protein in neonates primes for immune responses and enhances experimental autoimmune encephalomyelitis in adult animals. Eur. J. Immunol. 24, 1026-1032.
19. Paterson, P.Y. and Drobish, D. (1969) Cyclophosphamide: Effect on experimental allergic encephalomyelitis in Lewis rats. Science 165, 191-192.
20. Pender, M.P. (1987) Demyelination and neurological signs in experimental allergic encephalomyelitis. J. Neuroimmunol. 15, 11-24.
21. Raine, C.S., Traugott, U., Farooq, M., Bornstein, M.B. and Norton, W.T. (1981) Augmentation of immune-mediated demyelination by lipid haptens. Lab. Invest. 45, 174-182.
22. Rivero, V.E., Ferro, M.E., Romero-Piffiguer, M., Correa, S., Yranzo Volonté, N. and Riera, C.M. (1991) Antigen-induced inhibition of autoimmune response to rat male accessory glands: Distinct characteristics of IA and IE positive peritoneal cells. Eur. J. Immunol. 21, 1141-1146.
23. Roth, G.A., Monferran, C.G., Maggio, B. and Cumar, F.A. (1982) Central nervous system lipid alterations in rats with experimental allergic encephalomyelitis and its suppression by immunosuppressive drugs. Life Sci. 30, 859-866.
24. Roth, G.A., Yu, R.K. and Bornstein, M.B. (1983) Chemical analysis of organotypic cultures of mouse spinal cord in normal, demyelinative, and nondemyelinative conditions. J. Neurochem. 41, 1710-1717.
25. Roth, G.A. and Obata, K. (1991) Experimental allergic encephalomyelitis: Dissociation of immunochemical and clinicopathological responses in two strains of rats. Neurochem. Int. 19, 213-220.
26. Saoudi, A., Kuhn, J., Huygen, K., De Kozak, Y., Velu, T., Goldman, M., Druet, P. and Bellon, B. (1993) Th2 activated cells prevent experimental autoimmune uveoretinitis, a Th1-dependent autoimmune disease. Eur. J. Immunol. 23, 3096-3103.
27. Sharma, S.D., Bishwajit, N., Su, X.M., Green, D., Spack, E., Clark, B.R. and Subramaniam, S. (1991) Antigen-specific therapy of experimental allergic encephalomyelitis by soluble class II major histocompatibility complex-peptide complexes. Proc. Natl. Acad. Sci. USA 88, 11465-11469.
28. Sriram, S. and Steinman, L. (1983) Anti-IA antibody suppresses active encephalomyelitis: Treatment model for disease linked to IR genes. J. Exp. Med. 158, 1362-1367.
29. Stein, C.S., St. Louis, J., Gilbert, J.J. and Strejan, G.H. (1990) Treatment of spinal cord-induced experimental allergic encephalomyelitis in the Lewis rat with liposomes presenting central nervous system antigens. J. Neuroimmunol. 28, 119-130.
30. Swanborg, R.H. (1983) Autoimmune effector cells. V. A monoclonal antibody specific for rat helper T lymphocytes inhibits adoptive transfer of autoimmune encephalomyelitis. J. Immunol. 130, 1503-1508.
31. Swierkosz, J.E. and Swanborg, R.H. (1977) Immunoregulation of experimental allergic encephalomyelitis: Conditions for induction of suppressor cells and analysis of mechanism. J. Immunol. 119, 1501-1506.
32. Towbin, H., Staehelin, T. and Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Natl. Acad. Sci. USA 76, 4350-4354.
33. Weiner, L.H., Friedman, A., Miller, A., Khoury, S.J., Al-Sabbagh, A., Santos, L., Sayegh, M., Nussenblatt, R.B., Trentham, D.V. and Hafler, D.A. (1994) Oral tolerance: Immunologic mechanisms and treatment of animal and human organ-specific autoimmune diseases by oral administration of autoantigens. Ann. Rev. Immunol. 12, 809-837.
34. Wraith, D.C., Smilek, D.E., Mitchell, D.J., Steinman, L. and McDevitt, O.H. (1989) Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy. Cell 59, 247-255.
35. Zaller, D.M., Osman, G., Kanagawa, O. and Hood, L. (1990) Prevention and treatment of murine experimental allergic encephalomyelitis with T cell receptor Vb-specific antibodies. J. Exp. Med. 171, 1943-1955.