Synthesis and preliminary structure-activity relationships of 1-[(3-fluoro-4-pyridinyl)amino]-3-methyl-1H-indol-5-yl methyl carbamate (P10358), a novel acetylcholinesterase inhibitor

Bioorganic and Medicinal Chemistry Letters

Volumn 7, Issue 2, 1997, Pages 157-162

  Martin, Lawrence L ^a   Davis, Larry ^a   Klein, Joseph T ^a   Nemoto, Peter ^a   Olsen, Gordon E ^a   Bores, Gina M ^a   Camacho, Fernando ^a   Petko, Wayne W ^a   Rush, Douglas K ^a   Selk, David ^a   Smith, Craig P ^a   Vargas, Hugo M ^a   Winslow, James T ^a   Effland, Richard C ^a   Fink, David M ^a  

^a SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

1 [(3 FLUORO 4 PYRIDINYL)AMINO] 3 METHYL 1H INDOL 5 YL METHYLCARBAMATE; ACETYLCHOLINESTERASE; BESIPIRDINE; CHOLINESTERASE INHIBITOR; SCOPOLAMINE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DRUG ACTIVITY; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; LEARNING; MEMORY; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PASSIVE AVOIDANCE; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0031030952     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(96)00592-6     Document Type: Article

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