Synthesis and biological evaluation of a new reversely linked type of dual histamine H2 and gastrin receptor antagonist

Chemical and Pharmaceutical Bulletin

Volumn 45, Issue 1, 1997, Pages 116-124

  Kawanishi, Yasuyuki ^a   Ishihara, Shoichi ^a   Takahashi, Kimio ^a   Tsushima, Tadahiko ^a   Hagishita, Sanji ^a   Ishikawa, Michio ^a   Ishihara, Yasunobu ^a  

^a SHIONOGI AND CO LTD   (Japan)

Author keywords

anti ulcer agent; gastrin receptor antagonist; histamine H2 receptor antagonist

Indexed keywords

1 (2,3 DIHYDRO 1 METHYL 2 OXO 5 PHENYL 1H 1,4 BENZODIAZEPIN 3 YL) 3 (3 METHYLPHENYL)UREA; 1 [3 [N' [4 [2 (N AMINOSULFONYLAMIDINO)ETHYLTHIOMETHYL]THIAZOL 2 YL]GUANIDINOMETHYL]PHENYL] 3 (2,3 DIHYDRO 1 METHYL 2 OXO 5 PHENYL 1H 1,4 BENZODIAZEPIN 3 YL)UREA; FAMOTIDINE; GASTRIN ANTAGONIST; HISTAMINE H2 RECEPTOR ANTAGONIST; ROXATIDINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DRUG CLASSIFICATION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; GUINEA PIG; NONHUMAN; PEPTIC ULCER; STOMACH ACID SECRETION; STOMACH ULCER;

EID: 0031030635     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.45.116     Document Type: Article

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