Limited effect of sulphasalazine treatment in reactive arthritis. A randomised double blind placebo controlled trial

Annals of the Rheumatic Diseases

Volumn 56, Issue 1, 1997, Pages 32-36

  Egsmose, Charlotte ^a,b,g   Hansen, Troels Mørk ^b   Andersen, Lis Smedegaard ^c   Beier, Jannie Marion ^d   Christensen, Lene ^h   Ejstrup, Leif ^d   Peters, Niels Daugaard ^e   Van Der Heijde, Désirée M F M ^f  

^a Copenhagen Municipal Hospital ^*  (Denmark)

^b GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^c King Christian the Xth Hospital   (Denmark)

^d ODENSE UNIVERSITY HOSPITAL   (Denmark)

^e Hjørring Hospital   (Denmark)

^f MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^g SLAGELSE HOSPITAL   (Denmark)

^h Slagelse County Hospital ^*

Author keywords

[No Author keywords available]

Indexed keywords

PLACEBO; SALAZOSULFAPYRIDINE;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; LEUKOPENIA; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REACTIVE ARTHRITIS; TREATMENT OUTCOME;

EID: 0031030062     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.56.1.32     Document Type: Article

References (14)

1. McConkey B, Amos RS, Durham S, Forster PJG, Huball S, Walsh L. Sulphasalazine in rheumatoid arthritis. BMJ 1980;280:442-4.
2. Pullar T, Capell HA. Sulphasalazine: a "new" antirheumatic drug. Br J Rheumatol 1984;23:26-34.
3. Mielants H, Veys EM. HLA-B27 related arthritis and bowel inflammation. Part 1. Sulphasalazine (Salazopyrin) in HLA-B27 related reactive arthritis. J Rheumatol 1985; 12:287-93.
4. Mielants H, Veys EM, Cuvelier C, De Vos M, Botelberghe L. HLA- B27 related arthritis and bowel inflammation. Part 2. Ileocolonoscopy and bowel histology in patients with HLA-B27 related arthritis. J Rheumatol 1985; 12:294-8.
5. Mielants H, Veys EM, Joos R, Cuvelier C, de Vos M. Repeat ileo-colonoscopy in reactive arthritis. J Rheumatol 1987; 14:456-8.
6. Mielants H, Veys EM, Goemaere S, Goethals K, Cuvelier C, De Vos M. Gut inflammation in the spondyloarthropathies: clinical, radiological, biological and genetic features in relation to the type of histology. A prospective study. J Rheumatol 1991;18:1542-51.
7. Peppercorn MA. Sulphasalazine: pharmacology, clinical use, toxicity and related new drug development. Ann Intern Med 1984;101:377-86.
8. Mielants H, Veys EM, Joos R. Sulphasalazine (Salazaopyrin) in the treatment of enterogenic reactive synovitis and ankylosing spondylitis with peripheral arthritis. Clin Rheumatol 1986;5:80-3.
9. Stroehmann I, Wüstenhagen E, Martini M. Die Therapie seronegativer Oligo-artritiden mit Salazopyrin. Z Rheumatol 1987;46:79-82.
10. Trnavský K, Peliskova Z, Vácha J. Sulphasalazine in the treatment of reactive arthritis. Scand J Rheumatol 1988;suppl 67:76-9.
11. Dougados M, Maetzel A, Mijiyawa M, Amor B. Evaluation of sulphasalazine in the treatment of spondyloarthropathies. Ann Rheum Dis 1992;51:955-8.
12. Dougados M, van der Linden S, Leirisalo-Repo M, Huitfeldt B, Juhlin R, Veys E, et al. Sulphasalazine in the treatment of spondylarthopathy. Arthritis Rheum 1995; 38:618-27.
13. Wilkens RF, Arnett FC, Bitter T, Calin A, Fisher L, Ford DK, et al. Reiter's sydrome. Evaluation of preliminary criteria for definite disease. Arthritis Rheum 1981;24:844-9.
14. Dougados M, van der Linden S, Juhlin R, Huitfeld B, Amor B, Calin A, et al. The European spondylarthropathy study group preliminary criteria for the classification of spondylarthropathy. Arthritis Rheum 1991;34:1218-27.