Is Aluminum Toxicity Responsible for Uremic Pruritus in Chronic Hemodialysis Patients?

Nephron

Volumn 75, Issue 1, 1997, Pages 48-53

  Friga, Vasiliki ^a   Linos, Athena ^a   Linos, Dimitrios A ^b  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b HYGEIA HOSPITAL   (Greece)

Author keywords

Aluminum; Calcium phosphate product; Chronic renal failure; Hemodialysis; Pruritus

Indexed keywords

ALUMINUM; CALCIUM PHOSPHATE;

ADULT; AGED; ARTICLE; BLOOD LEVEL; CHRONIC KIDNEY FAILURE; FEMALE; HEMODIALYSIS; HEMODIALYSIS PATIENT; HUMAN; LONG TERM EXPOSURE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PRURITUS;

EID: 0031029113     PISSN: 16608151     EISSN: 22353186     Source Type: Journal    
DOI: 10.1159/000189499     Document Type: Article

References (22)

1. Matsumoto M. Ichimaru K. Horie A: Prurilus and mast cell proliferation of the skin in end-stage renal failure. Clin Nephrol 1985:23:285-288.
2. Young AW. Sweeney EW. David DS. Chcigh J. Hochgclcrcnt EL, Sakai S. Stenzel KH. Rubin AL: Dermatologic evaluation of pruritus in patients on hemodialysis. NY State J Med 1973: 73:2670-2674.
3. Gilchrest BA, Stern RS. Steinman TI. Brown RS, Arndt KA, Anderson WW: Clinical features of pruritus among patients undergoing maintenance hemodialysis. Arch Dermatol 1982:118:154-156.
4. Massry SG. Popovtzcr MM. Coburn JW. Makoff DL, Maxwell MH, Kleeman CR: Intractable pruritus as a manifestation of secondary hyperparathyroidism in uremia: Disappearance of itching after subtotal hyperparathyroidectomy. N Engl J Med 1968:279:697-700.
5. Blachley JD. Blankenship DM. Menter A. Parker TF III, Knöchel JP: Uremic pruritus: Skin divalent ion content and response to ultraviolet phototherapy. Am J Kidney Dis 1985: 5:237-241.
6. Berne B. Vahlquist A, Fischer T. Danieisson B, Berne C: UV treatment of uremic pruritus reduces the vitamin A content of the skin. Eur J Clin Invest 1984; 14:203-206.
7. Graf H, Kovarik J, Stummvoll HK. Wolf A: Disappearance of uremic pruritus after lowering dialysate magnesium concentration. Br Med J 1979;ii: 1478-1479.
8. Weismann K, Graham RM: Systemic disease and the skin; in Champion RH. Burton JL. Ebling FJG (eds): Textbook of Dermatology, ed 5. Oxford, Blackwell, 1992. pp 2407-2453.
9. Ncintan RS. Bisehel MD. Lukes RJ: Uremia and mast cell proliferation. Lancet 1972:i:959.
10. Wills MR. Savory J: Aluminium poisoning: Dialysis encephalopathy, osteomalacia, and anemia. Lancet 1983;ii:29-34.
11. Altman P: Aluminium toxicity in dialysis patients: No evidence for a threshold serum aluminium concentration. Nephrol Dial Transplant 1993:(suppl 1):25-34.
12. D'Haesc PC. Van de Vyver FL. de Wolff FA, Dc Broe ME: Measurement of aluminium in serum, blood, urine and tissues of chronic hc-modialyzed patients by use of electrothermal atomic absorption spectrometry. Clin Chem 1985:31:24-29.
13. Carmichael AJ. McHugh MM, Martin AM: Serological markers of renal itch in patients receiving long term hemodialysis. BMJ 1988: 296:1575.
14. Stahle-Backdahl M. Hagcrmark O, Lins LE. Torring O. Hilliges M, Johansson O: Experimental and immunohistochemical studies on the possible role of parathyroid hormone in uremic patients. J Intern Med 1989:225:411-415.
15. Sampson B, Curtis JR, Davies S: Survey of blood lead and plasma aluminium concentrations in patients of a renal unit. Nephrol Dial Transplant 1989;4:375-381.
16. D'Haesc PC. Clement JP. Elseviers MM. Lamberts LV. Van de Vyver FL. Visser FI. De Broc ME: Value of serum aluminium monitoring in dialysis patients: A multicentre study. Nephrol Dial Transplant 1990:5:45-53.
17. 7.
18. Vein NK, Hatel T. Justesen O. Norholm A: Aluminium allergy. Contact Dermatol 1986: 15:295-297.
19. Castclain P-Y. Castelain M, Vervloet D. Garbe L. Mallet B: Sensitization to aluminium by aluminium-precipitated dust and pollen extracts. Contact Dermatol 1988:19:58-60.
20. Rainier SS. Archer ME, Jorizzo JL: Metastatic calcinosis cutis. Cutis 1983;32:463-465.
21. Zins B. Zingraff J, Basile C. Petitclcrc T. Urena P. Bardin T. Drucke T: Tumoral calcinosis in hemodialysis patients: Possible role of aluminium intoxication. Nephron 1992;60:260-267.
22. Geffriaud C. Alline E, Page B. Zingraff J, Joequel JP. Bardin T, Drueke T: Decrease of tumor-like calcification in uremia despite aggravation of secondary hyperparathyroidism: Acase report. Clin Nephrol 1992;38:158-161.