Inhibition of collagen synthesis, smooth muscle cell proliferation, and injury-induced intimal hyperplasia by halofuginone

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 17, Issue 1, 1997, Pages 194-202

  Nagler, Arnon ^a   Miao, Hua Quan ^a   Aingorn, Helena ^a   Pines, Mark ^b   Genina, Olga ^b   Vlodavsky, Israel ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b VOLCANI CENTER   (Israel)

Author keywords

collagen type I; extracellular matrix; fibroblast growth factor; intimal proliferation; vascular smooth muscle cell

Indexed keywords

COLLAGEN; COLLAGEN TYPE 1; HALOFUGINONE;

ANIMAL CELL; ARTERIOSCLEROSIS; ARTERY INJURY; ARTERY INTIMA PROLIFERATION; ARTERY OCCLUSION; ARTERY WALL; ARTICLE; CELL PROLIFERATION; COLLAGEN SYNTHESIS; DNA SYNTHESIS; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; NONHUMAN; PRIORITY JOURNAL; RESTENOSIS; VASCULAR SMOOTH MUSCLE;

EID: 0031028794     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.17.1.194     Document Type: Article

References (5)

1. Fuster V, Badimon L, Badimon JJ, Chesebro JH. The pathogenesis of coronary artery disease and the acute coronary syndromes. N Engl J Med. 1992;326:242-245.
2. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature. 1993;362:801-809.
3. McBride W, Lange RA, Hillis LD. Restenosis after successful coronary angioplasty. N EngI J Med. 1988;318:1734-1737.
4. Bourassa M. Silent myocardial ischemia after coronary angioplasty: distinguishing the shadow from the substances. J Am Coll Cardiol. 1992;19:1410-1411.
5. Ferns GAA, Rains EW, Sprugel KH, Motani AS, Reidy MA, Ross R. Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF. Science. 1991;253:1129-1132.