The role of carotid chemoreceptors in the effects of hypoxia on renal blood flow in the late gestation sheep fetus

Experimental Physiology

Volumn 82, Issue 1, 1997, Pages 183-192

  Green, Lucy R ^a   Bennet, Laura ^a   Robson, Stephen ^b   Hanson, Mark A ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CAROTID BODY CHEMORECEPTOR; CAROTID SINUS NERVE; CONTROLLED STUDY; FEMALE; FETUS; HYPOXIA; KIDNEY BLOOD FLOW; NERVE TRANSECTION; NONHUMAN; PREGNANCY; SHEEP; URINE VOLUME;

EID: 0031028753     PISSN: 09580670     EISSN: None     Source Type: Journal    
DOI: 10.1113/expphysiol.1997.sp004007     Document Type: Article

References (36)

1. ARNOLD-ALDEA, S. A., AUSLENDER, R. A. & PARER, J. T. (1991). The effect of the inhibition of prostaglandin synthesis on renal blood flow in fetal sheep. American Journal of Obstetrics and Gynecology 165, 185-190.
2. BARTELDS, B., VAN BEL, F, TEITEL, D. F. & RUDOLPH, A. M. (1993). Carotid, not aortic, chemoreceptors mediate the fetal cardiovascular responses to acute hypoxemia in lambs. Pediatric Research 34, 51-55.
3. BEGUIN, F., DUNNIHOO, D. R. & QUILLIGAN, E. J. (1974). Effect of carbon dioxide elevation on renal blood flow in the fetal lamb in utero. American Journal of Obstetrics and Gynecology 119, 630-637.
4. BEHM, R., MEWES, H., DEMUINCK KEIZER, W. H., UNGER, T. & RETTIG, R. (1993). Cardiovascular and renal effects of hypoxia in conscious carotid body-denervated rats. Journal of Applied Physiology 74, 2795-2800.
5. BOGAERT, G. A., KOGAN, B. A. & MEVORACH, R. A. (1993). Effects of endothelium-derived nitric oxide on renal hemodynamics and function in the sheep fetus. Pediatric Research 34, 755-761.
6. BRACE, R. A., WLODEK, M. E., MCCRABB, G. J. & HARDING, R. (1994). Swallowing and urine flow responses of ovine fetuses to 24 h of hypoxia. American Journal of Physiology 266, R1345-1352.
7. COCK, M. L., WLODEK, M. E., HOOPER, S. B., MCCRABB, G. J., HARDING. R. (1994). The effects of twenty-four hours of reduced uterine blood flow on fetal fluid balance in sheep. American Journal of Obstetrics and Gynecology 170, 1442-1451.
8. COHN, H. E., SACKS, E. J., HEYMANN, M. A. & RUDOLPH, A. M. (1974). Cardiovascular responses to hypoxemia and acidemia in fetal lambs. American Journal of Obstetrics and Gynecology 120, 817-824.
9. COURT, D. J., PARER, J. T., BLOCK, B. S. B. & LLANOS, A. J. (1984). Effects of beta-adrenergic blockade on blood flow distribution during hypoxaemia in fetal sheep. Journal of Developmental Physiology 6, 349-358.
10. DANIEL, S. S., YEH, M.-N., BOWE, E. T., FUKUNAGA, A. & JAMES, L. S. (1975). Renal response of the lamb fetus to partial occlusion of the umbilical cord. Journal of Pediatrics 87, 788-794.
11. GIUSSANI, D. A. G., SPENCER, J. A. D., MOORE, P. J., BENNET, L. & HANSON, M. A. (1993). Afferent and efferent components of the cardiovascular reflex responses to acute hypoxia in term fetal sheep. Journal of Physiology 461, 431-449.
12. GREEN, L. R., MCGARRIGLE, H. H. G., BENNET, L. & HANSON, M. A. (1994). The effect of acute hypoxaemia on plasma angiotensin II in intact and carotid sinus-denervated fetal sheep. Journal of Physiology 476.P, 81-82P.
13. GREEN, L. R., MCGARRIGLE, H. H. G., BENNET, L. & HANSON, M. A. (1995). The role of endothelin-1 in cardiovascular responses to acute hypoxia in late gestation fetal sheep. Japanese Journal of Physiology 45, S27.
14. GRONE, H.-J., LAUE, A. & FUCHS, E. (1990). Localization and quantification of [125I]-endothelin binding sites in human fetal and adult kidneys - relevance to renal ontogeny and pathophysiology. Klinische Wochenschrift 68, 758-767.
15. 1adrenoceptor stimulation in sheep. American Journal of Physiology 267, R990-998.
16. HERIN, P., KIM, J. K., SCHRIER, R. W., MESCHIA, G. & BATTAGLIA, F. C. (1988). Ovine fetal response to water deprivation: aspects on the role of vasopressin. Quarterly Journal of Experimental Physiology 73, 931-940.
17. ITO, S., JUNCOS, L. A., NUSHIRO, N., JOHNSON, C. S. & CARRETERO, O. A. (1991). Endothelium-derived relaxing factor modulates endothelin action in afferent arterioles. Hypertension 17, 1052-1056.
18. JENSEN, A. & BERGER, R. (1993). Regional distribution of cardiac output. In Fetus and Neonate. Physiology and Clinical Applications, The Circulation, ed. HANSON, M. A., SPENCER, J. A. D. & RODECK C. H., pp. 23-74. Cambridge University Press, Cambridge, UK.
19. LERMAN, A., HILDEBRAND, F. L., AARHUS, L. L. & BURNETT, J. C. (1991). Endothelin has biological actions at pathophysiological concentrations. Circulation 83, 1808-1814.
20. LINGWOOD, B., HARDY, K. J., HORACEK, I., MCPHEE, M. L., SCOGGINS, B. A. & WINTOUR, E. M. (1978). The effects of antidiuretic hormone on urine flow and composition in the chronically-cannulated ovine fetus. Quarterly Journal of Experimental Physiology 63, 315-330.
21. MATTHEWS, J. N. S., ALTMAN, D. G., CAMPBELL, M. J. & ROYSTON, P. (1990). Analysis of serial measurements in medical research. British Medical Journal 300, 230-235.
22. MILLARD, R. W., BAIG, H. & VATNER, S. F. (1979). Prostaglandin control of the renal circulation in response to hypoxemia in the fetal lamb in utero. Circulation Research 45, 172-179.
23. 2. Journal of Developmental Physiology 16, 133-138.
24. NAKAMURA, K. T., AYERS, N. A., GOMEZ, R. A. & ROBILLARD, J. E. (1985). Renal responses to hypoxemia during renin-angiotensin system inhibition in fetal lambs. American Journal of Physiology 249, R116-124.
25. NICOLAIDES, K. H., PETERS, M. T., VYAS, S., RABINOWITZ, R., ROSEN, D. J. D. & CAMPBELL, S. (1990). Relation of urine production to oxygen tension in small-for-gestational-age fetuses. American Journal of Obstetrics and Gynecology 162, 387-391.
26. POLLOCK, D. M. & OPGENORTH, T. J. (1993). Evidence for endothelin-induced renal vasoconstriction independent of ET receptor activation. American Journal of Physiology 264, R222-226.
27. REUSS, M. L., PARER, J. T. HARRIS, J. L. & KREUGER, T. R. (1982). Hemodynamic effects of alpha-adrenergic blockade durina hypoxia in fetal sheep. American Journal of Obstetrics and Gynecology 142, 410-415.
28. ROBILLARD, J. E., NAKAMURA, K. T. & DIBONA, G. F. (1986). Effects of renal denervation on renal responses to hypoxemia in fetal lambs. American Journal of Physiology 250, F294-301.
29. ROBILLARD, J. E., PORTER, C. C. & JOSE, P. A. (1994). Structure and function of the developing kidney. In Pediatric Nephrology, ed. HOLLIDAY, M. A., BARRATT, T. M., AVNER, E. D. & KOGAN, B. A., pp. 21-39. Williams & Wilkins, Baltimore, MD, USA.
30. ROBILLARD, J. E., SMITH, F. G., SEGAR, J. L., MERRILL, D. C. & JOSE, P. A. (1992). Functional role of renal sympathetic innervation during fetal and postnatal development. News in Physiological Sciences 7, 130-133.
31. ROBILLARD, J. E., WEITZMAN, R. E., BURMEISTER, L. & SMITH, F. G. (1981). Developmental aspects of the renal response to hypoxemia in the lamb fetus. Circulation Research 48, 128-138.
32. SCHUIJERS, J. A., WALKER, D. W., BROWNE, C. A. & THORBURN, G. D. (1986). Effect of hypoxemia on plasma catecholamines in intact and immunosympathectomized fetal lambs. American Journal of Physiology 251, R893-900.
33. VYAS, S., NICOLAIDES, K. H. & CAMPBELL, S. (1989). Renal artery flow-velocity waveforms in normal and hypoxemic fetuses. American Journal of Obstetrics and Gynecology 161, 168-172.
34. WALKER, M. P. R., MOORE, T. R., CHEUNG, C. Y. & BRACE, R. A. (1992). Indomethacin-induced urinary flow rate reduction in the ovine fetus is associated with reduced free water clearance and elevated plasma arginine vasopressin levels. American Journal of Obstetrics and Gynecology 167, 1723-1731.
35. WALKER, V., BENNET, L., GREEN, L. R., GNANAKUMARAN, K. & HANSON, M. A. (1996). Effects of hypoxia on urinary organic acid and hypoxanthine excretion on fetal sheep. Pediatric Research 40, 309-318.
36. WLODEK, M. E., CHALLIS, J. R. G., RICHARDSON, B. & PATRICK, J. (1989). The effects of hypoxemia with progressive acidemia on fetal renal function in sheep. Journal of Developmental Physiology 12, 323-328.