Transplantation and chimera as extended self

Medical Hypotheses

Volumn 48, Issue 1, 1997, Pages 63-69

  Chigira, M ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERA; DNA SEQUENCE; HUMAN; HYPOTHESIS; PRIORITY JOURNAL; REVIEW; SYMBIOSIS; TRANSPLANTATION;

EID: 0031028073     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-9877(97)90025-6     Document Type: Article

References (90)

1. Charlton B, Auchincloss H, Fathman G. Mechanisms of transplantation tolerance. Annu Rev Immunol 1994; 12: 707-734.
2. Chigira M, Arita S, Watanabe H. Myth of tumor immunology. Int J Oncol 1993; 3: 645-654.
3. Chigira M, Shinozaki T, Watanabe H. AIDS from an oncological viewpoint: paradoxical immunodeficiency by helper T cell proliferation and senescence. Int J Oncol 1994; 4: 101-107.
4. Chigira M, Shinozaki T, Watanabe H. Theoretical basis of paraneoplastic autoimmune disorders. Oncol Rep 1995; 2: 397-415.
5. Dighiero G, Guilbert B, Fernand J, Lymberi P, Danon F, Avrameas S. Thirty-six human monoclonal immunoglobulins with antibody activity against cytoskeleton proteins, thyroglobulin, and native DNA: immunologic studies and clinical correlation. Blood 1983; 62: 264-270.
6. Dighiero G, Lymberi P, Guilbert B, Ternyck T, Avrameas S. Natural autoantibodies constitute a substantial part of normal circulating immunoglobulins. Ann NY Acad Sci 1985; 475: 133-145.
7. Steele E J, Cunningham A J. High proportion of Ig-producing cells making autoantibody in normal mice. Nature 1978; 274: 483-484.
8. Avrameas S, Guilbert B, Mahana W, Matsiota P, Ternyck T. Recognition of self and non-self constituents by polyspecific autoreceptors. Int Rev Immunol 1988; 3: 1-15.
9. Wing M G. The molecular basis for polyspecific antibody. Clin Exp Immunol 1995; 99: 313-315.
10. Underwood J R, Pedersen J S, Chalmers P J, Toh B H. Hybrids from normal, germ free, nude and neonatal mice mice produce monoclonal autoantibodies to eight different intracellular structures. Clin Exp Immunol 1985; 60: 417-426.
11. Stoller B D, Schwartz R S. Monoclonal anti-DNA antibodies: the targets and origins of SLE autoantibodies. Ann NY Acad Sci 1986; 475: 192-199.
12. Naparstek Y, Plotz P H. The role of autoantibodies in autoimmune disease. Annu Rev Immunol 1993; 11: 79-104.
13. Souroujon M, White-Scharf M E, Andre-Schwartz J, Gefter M L, Schwartz R S. Preferential autoantibody reactivity of the preimmune B cell repertoire in normal mice. J Immunol 1988; 140: 4173-4179.
14. Mouthon L, Nobrega A, Nicolas N et al. Invariance and restriction toward a limited set of self-antigens characterize neonatal IgM antibody repertoires and prevail in autoreactive repertoires of healthy adults. Proc Natl Acad Sci (USA) 1995; 92: 3839-3843.
15. Lymberi P, Dighiero G, Ternyck T, Avrameas S. A high incidence of cross-reactive idiotypes among murine natural autoantibodies. Eur J Imunnol 1985; 15: 702-707.
16. Jemmerson R, Margoliash E. Specificity of the antibody response of rabbits to a self-antigen. Nature 1979; 282: 468-471.
17. Freitas A A, Vialo A C, Sundblad A, Heusser C, Coutinho A. Normal serum immunoglobulins participate in the selection of peripheral B cell repertoires. Proc Natl Acad Sci (USA) 1991; 88: 5640-5644.
18. Hurez V, Kaveri S V, Kazatchkine M D. Expression and control of the natural autoreactive IgG repertoire in normal human serum. Eur J Immunol 1993; 23: 783-789.
19. Gonzalez R, Charlemagne J, Mahana W, Avrameas S. Specificity of natural serum antibodies present in phylogenetically distinct fish species. Immunology 1988; 63: 31-36.
20. H gene families. J Exp Med 1988; 168: 417-435.
21. Wiener E, Wickramasinghe S N. Natural autoantibodies may play a role in ineffective erythropoiesis during megaloblastic haemopoiesis. Clin Exp Immunol 1991; 83: 121-125.
22. Hilson J L, Oppliger I R, Sasso E H, Milner E C B, Wener M H. Emerging human B cell repertoire: influence of developmental stage and interindividual variation. J Immunol 1992; 149: 3741-3752.
23. H gene family expression. J Exp Med 1988; 168: 589-603.
24. Nobrega A, Haury M, Grandien A, Malancheve E, Sundblad A, Coutinho A. Global analysis of antibody repertoires. II. Evidence for specificity, self-selection and the immunological "homunculus" of antibodies in normal serum. Eur J Immunol 1993; 23: 2851-2859.
25. Burnet M. Self and Non-self. Melbourne: Melbourne University Press, 1970.
26. Jerne N K. The immune system. Sci Am 1973; 229: 52-60.
27. Jerne N K. Towards a network theory of the immune system. Ann Immunol Paris 1975; 125C: 373-389.
28. Chigira M. Self and non-self: duality of immunity. Med Hypotheses 1994; 43: 6-10.
29. Chigira M. Origin of blood group antigens: a self-declaration mechanism in somatic cell society. Med Hypotheses 1996; 46: 290-294.
30. Nicholson-Weller A, March J P, Rosenfeld S I, Austen K F. Affected erythrocytes of patients with paroxysmal nocturnal hemoglobinuria are deficient in the complement regulatory protein, decay accelerating factor. Proc Natl Acad Sci (USA) 1983; 80: 5066-5070.
31. Rosse W F. Paroxysmal nocturnal hemoglobinuria: the biochemical defects and the clinical syndrome. Blood Rev 1989; 3: 192-200.
32. Miyata T, Takeda J, Iida Y et al. The cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis. Science 1993; 259: 1318-1320.
33. Moretta L, Ciccone E, Mingari M C, Biassoni R, Moretta A. Human natural killer cells: origin, clonality, specificity, and receptors. Adv Immunol 1994; 55: 341-380.
34. Karre K. Express yourself or die: peptides, MHC molecules, and NK cells. Science 1995; 267: 978-979.
35. Salcedo M, Hoglund P, Ljunggren H G. Natural killer cell interaction with murine allogeneic MHC class I molecules. Transplantation 1995; 60: 281-286.
36. Tanaka A, Tanaka K, Kitai T et al. Living related liver transplantation across ABO blood groups. Transplantation 1994; 58: 548-553.
37. Terasaki P I, Cecka J M, Gjertson D W, Takemoto S. High survival rates of kidney transplants from spousal and living unrelated donors. N Engl J Med 1995; 333: 333-336.
38. Tanabe K, Takahashi K, Sonoda K et al. ABO-incompatible living kidney donor transplantation: results and immunological aspects. Transplant Proc 1995; 27: 1020-1023.
39. Engelhard V H. Structure of peptides associated with class I and class II MHC molecules. Annu Rev Immunol 1994; 12: 181-207.
40. Benham A, Tulp A, Neefjes J. Synthesis and assembly of MHC-peptide complexes. Immunol Today 1995; 16: 359-362.
41. Cresswell P. Assembly, transport, and function of MHC class II molecules. Annu Rev Immunol 1994; 12: 259-293.
42. kmolecule. J Immunol 1988; 141: 4124-4128.
43. Takahashi H, Komano H, Natori S. Expression of the lectin gene in Sarcophaga peregrina during normal development and under conditions where the defense mechanism is activated. J Insect Physiol 1986; 32: 771-779.
44. Natori S. Dual functions of insect immunity proteins in defense and development. Res Immunol 1990; 141: 938-939.
45. DiMarzo S J, Cohen N. Immunogenetic aspects of in vivo allotolerance induction during the ontogeny of Xenopus laevis. Immunogenetics 1982; 16: 103-116.
46. DiMarzo S J, Cohen N. An in vivo study of the ontogeny of alloreactivity in the frog, Xenopus laevis. Immunology 1982; 45: 39-48.
47. Li H, El-Ezz A Y A, Gambrell B E, Ildstad S T. Mixed xenogeneic chimerism and tolerance. III. A nonlethal approach to induce donor-specific transplantation tolerance to simultaneous islet xenografts. Transplantation 1995; 60: 59-65.
48. Ono M, Tochinai S. Demonstration of cells possessing tolerance-inducing activity in Xenopus laevis rendered tolerant perimetamorphically. Transplantation 1995; 60: 66-70.
49. Komano H, Natori S. Participation of Sarcophaqa peregrina humoral lectin in the lysis of sheep red blood cells injected into the abdominal cavity of larvae. Dev Comp Immunol 1985; 9: 31-40.
50. Jacob F. Mouse teratocarcinoma and embryonic antigens. Immunol Rev 1977; 33: 3-32.
51. Okada T S. Transdifferentiation in animal cells: fact or artifact? Dev Growth Differ 1986; 28: 213-221.
52. Carsons S, Clausen H, Wolf J. Expression of a developmentally regulated epitope on fibronectins from the synovial fluid of patients with rheumatic disease. J Rheumatol 1994; 21: 1888-1891.
53. Vaz N M, Varela F J. Self and non-sense: an organism-centered approach to immunity. Med Hypotheses 1978; 4: 231-267.
54. Maruyama M. The second cybernetics: deviation-amplifying mutual causal processes. Am Sci 1963; 51: 164-179.
55. Burwell R G. The role of lymphoid tissue in morphostasis. Lancet 1963; II: 69-74.
56. Cunliffe J. Morphostasis and immunity. Med Hypotheses 1995; 44: 89-96.
57. Giralt S A, Champlin R E. Leukemia relapse after allogeneic bone marrow transplantation: a review. Blood 1994; 84: 3603-3612.
58. Scharf S J, Smith A G, Hansen J A, McFarland C, Erlich H A. Quantitative determination of bone marrow transplantation engraftment using fluorescent polymerase chain reaction primers for human identity markers. Blood 1995; 85: 1954-1963.
59. Ferrara J L M, Deeg H J. Graft-versus-host disease. N Engl J Med 1991; 324: 667-673.
60. Vogelsang G B, Hess A D. Graft-versus-host disease: new directions for persistent problem. Blood 1994; 84: 2061-2067.
61. Ikehara S, Good R A, Nakamura T et al. Rationale for bone marrow transplantation in the treatment of autoimmune diseases. Proc Natl Acad Sci (USA) 1985; 82: 2483-2487.
62. Ikehara S, Ohtsuki H, Good R A et al. Prevention of type I diabetes in nonobese diabetic mice by allogeneic bone marrow transplantation. Proc Natl Acad Sci (USA) 1985; 82: 7743-7747.
63. Glazier A, Tutschka P J, Farmer E R, Santas G W. Graft-versus-host disease in cyclosporin A-treated rats after syngeneic and autologous bone marrow reconstitution. J Exp Med 1983; 158: 1-8
64. Hess A D, Horwitz L, Beschorner W E, Santos G W. Development of graft-vs-host disease-like syndrome in cyclosporine-treated rats after syngeneic bone marrow transplantation. I. Development of cytotoxic T lymphocytes with apparent polyclonal anti-Ia specificity, including autoreactivity. J Exp Med 1985; 161: 718-730.
65. Ault K A, Antin J H, Ginsburg D et al. Phenotype of recovering lymphoid cell population after bone marrow transplantation. J Exp Med 1985; 161: 1483-1502.
66. Ildstad S T, Sachs D H. Reconstitution with syngeneic plus allogeneic or xenogeneic bone marrow leads to specific acceptance of allografts or xenografts. Nature 1984; 307: 168-170.
67. Kaufman C L, Gaines B A, Ildstad S T. Xenotransplantation. Annu Rev Immunol 1995; 13: 339-367.
68. McCune J M, Namikawa R, Kaneshima H, Schultz L D, Lieberman M, Weissman I L. The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function. Science 1988; 241: 1632-1639.
69. Namikawa R, Weilbaecher K N, Kaneshima H, Yee E J, McCune J M. Long-term human hematopoiesis in the SCID-hu mouse. J Exp Med 1990; 172: 1055-1063.
70. Gao E K, Lo D, Cheney R, Kanagawa O, Sprent J. Abnormal differentiation of thymocytes in mice treated with cyclosporin A. Nature 1988; 336: 176-179.
71. Shinozawa T, Beschorner W E, Hess A D. The thymus and prolonged administration of cyclosporine: irreversible immunopathologic changes associated with autologous pseudo-graft-versus-host disease. Transplantation 1990; 50: 106-111.
72. Severino M E, Laulis M K, Horwitz L R, Hess A D. Cyclosporine preferentially inhibits clonal deletion of CD8 positive T-cells with an MHC class II restricted autoreactive T-cell receptor. Transplantation 1993; 25: 520-523.
73. Sayegh M H, Perico N, Gallon L et al. Mechanisms of acquired thymic unresponsiveness to renal allografts: thymic recognition of immunodominant allo-MHC peptides induced peripheral T cell anergy. Transplantation 1994; 58: 125-132.
74. Nakamura T, Good R A, Yasumizu R et al. Successful liver allografts in mice by combination with allogeneic bone marrow transplantation. Proc Natl Acad Sci (USA) 1986; 83: 4529-4532.
75. Ikehara S, Kawamura M, Takao F et al. Organ-specific and systemic autoimmune diseases originated from defects in hematopoietic stem cells. Proc Natl Acad Sci (USA) 1990; 87: 8341-8344.
76. Taguchi O, Nishizuka Y. Autoimmune oophoritis in thymectomized mice: T cell requirement in adoptive cell transfer. Clin Exp Immunol 1980; 42: 324-331.
77. Bonomo A, Kehn P J, Shevach E M. Post-thymectomy autoimmunity: abnormal T-cell homeostasis. Immunol Today 1995; 16: 61-67.
78. Bevan M J. In a radiation chimera, host H-2 antigens determine immune responsiveness of donor cytotoxic cells. Nature 1977; 269: 417-418.
79. Sprent J, Webb S R. Function and specificity of T cell subsets in the mouse. Adv Immunol 1987; 41: 39-133.
80. Jameson S C, Hogquist K A, Bevan M J. Positive selection of thymocytes. Annu Rev Immunol 1995; 13: 93-126.
81. Moiser D E, Gulizia R J, Baired S M, Wilson D B. Transfer of a functional human immune system to mice with severe combined immunodeficiency. Nature 1988; 335: 256-259.
82. Fraser C C, Kaneshima H, Hansteen G, Kilpatrick M, Hoffman R, Chen B P. Human allogeneic stem cell maintenance and differentiation in a long-term multilineage SCID-hu graft. Blood 1995; 86: 1680-1693.
83. + cytotoxic T lymphocytes in association with a class I MHC protein. Cell 1994; 69: 989-998.
84. Sykulev Y, Brunmark A, Jackson M, Cohen R J, Peterson P A, Eiden H N. Kinetics and affinity of reactions between and antigen-specific T cell receptor and peptide-MHC complexes. Immunity 1994; 1: 15-22.
85. Sakaguchi S, Fukuma K, Kuribayashi K, Masuda T. Organspecific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance: deficit of a T cell subset as a possible cause of autoimmune disease. J Exp Med 1985; 161: 72-87.
86. Smith Y, Sakamoto Y, Kasai K, Tung K. Effector and regulatory cells in autoimmune oophoritis elicited by neonatal thymectomy. J Immunol 1991; 147: 2928-2933.
87. Matzinger P. Tolerance, danger, and the extended family. Annu Rev Immunol 1994; 12: 991-1045.
88. Chigira M, Watanabe H. Differentiation as symbiosis. Med Hypotheses 1994; 43: 17-18.
89. Dawkins R. The Selfish Gene. Oxford: Oxford University Press, 1976.
90. Dawkins R. The Extended Phenotype: The Gene as the Unit of Selection. Oxford: Oxford University Press, 1982.