Assessment of affinity constants by rapid solid phase detection of equilibrium binding in a flow system

Journal of Immunological Methods

Volumn 201, Issue 2, 1997, Pages 189-206

  Piehler, Jacob ^a   Brecht, Andreas ^a   Giersch, Thomas ^b   Hock, Bertold ^b   Gauglitz, Günter ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

affinity constant; antibody affinity; label free affinity probe; monoclonal anti s triazine antibody

Indexed keywords

IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G; TRIAZINE;

ANTIBODY AFFINITY; ANTIBODY DETECTION; ANTIGEN ANTIBODY COMPLEX; ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; KINETICS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIBODY AFFINITY; ANTIGEN-ANTIBODY REACTIONS; DIFFUSION; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULIN G; KINETICS; LIGANDS; MICE; MICE, INBRED BALB C; RHEOLOGY; TRIAZINES;

EID: 0031027480     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(96)00222-0     Document Type: Article

References (36)

1. Brecht, A., Gauglitz, G. and Polster, J. (1993) Interferometric immunoassay in a FIA-system: a sensitive and rapid approach in label-free immunosensing. Biosens. Bioelectron. 8, 387-392.
2. Cush, R., Cronin, J.M., Stewart, W.J., Maule, C.H., Molloy, J. and Goddard, N.J. (1993) The resonant mirror: a novel optical biosensor for direct sensing of biomolecular interactions. Part I: principle of operation and associated instrumentation. Biosens. Bioelectron. 8, 347-353.
3. Eddowes, M.J. (1987) Direct immunochemical sensing: Basic chemical principles and fundamental limitations. Biosensors 3, 1-15.
4. Ekins, R. (1994) Immunoassay: recent developments and future directions. Nucl. Med. Biol. 21, 495-521.
5. Fägerstam, L.G., Frostell-Karlsson, A., Karlsson, R., Persson, B. and Rönnberg, I. (1992) Biospecific interaction analysis using surface plasmon resonance detection applied to kinetic, binding site and concentration analysis. J. Chromatogr. 597, 397-410.
6. Feldman, H.A. (1972) Mathematical theory of complex ligand binding systems at equilibrium. Some methods for parameter fitting. Anal. Biochem. 48, 317.
7. Fisher, R.J. and Fivash, M. (1994) Surface plasmon resonance based methods for measuring the kinetics and binding affinities of biomolecular interactions. Curr. Opin. Biotechnol. 5, 389-395.
8. Friguet, B., Chaffotte, A.F., Djavadi-Ohaniance, L. and Goldberg, M.E. (1985) Measurements of the true affinity constant in solution of analyte-antibody complexes by enzyme-linked immunosorbent assay. J. Immunol. Methods 77, 305-319.
9. Gauglitz, G., Brecht, A., Kraus, G. and Nahm, W. (1993) Chemical and biochemical sensors based on interferometry at thin (multi-)layers. Sens. Act. B 11, 21-27.
10. Giersch, T. (1993) A new monoclonal antibody for sensitive detection of atrazine with immunoassay in microtiter plate and dipstick format. J. Agric. Food Chem. 41, 1006-1011.
11. Giersch, T. and Hock, B. (1990) Production of monoclonal antibodies for the determination of s-triazines with enzym immunoassay. Food Agric. Immunol. 2, 85-97.
12. Glaser, R.W. (1993) Antigen-antibody binding and mass transport by convection and diffusion to a surface: A two-dimensional computer model of binding and dissociation kinetics. Analyt. Biochem. 213, 153-161.
13. Hetherington, S. (1990) Solid phase disruption of fluid phase equilibrium in affinity assays with ELISA. J. Immunol. Methods 138, 195-202.
14. Jönsson, U., Fägerstam, L., Ivarsson, B., Johnsson, B., Karlsson, R., Lundh, K., Löfas, S., Persson, B., Roos, H., Rönnberg, I., Sjölander, S. Stenberg, E., Stahlberg, R., Urbaniczky, C., Östlin, H. and Malmquist, M. (1991) Real-time biospecific interaction analysis using surface plasmon resonance and a sensor chip technology. Biotechniques 11, 620-627.
15. Karlsson, R. (1994) Real-time competitive kinetic analysis of interactions between low molecular weight ligands in solution and surface-immobilized receptors. Anal. Biochem. 221, 142-151.
16. Karlsson, R., Michaelsson, A. and Mattson, L. (1991) Kinetic analysis of monoclonal antibody-antigen interactions with a new biosensor based analytical system. J. Immunol. Methods 145, 229-240.
17. Kramer, K., Giersch, T. and Hock, B. (1994) Magnetic bead selection of hybridomas producing pesticide antibodies. Food Agric. Immunol. 6, 5-16.
18. Liedberg, B., Nylander, C. and Lundström, I. (1983) Surface plasmon resonance for gas detection and biosensing. Sens. Act. 4, 299-304.
19. Lukosz, W. (1991) Principles and sensitivities of integrated optical and surface plasmon sensors for direct affinity sensing and immunosensing. Biosens. Bioelectron. 6, 215-225.
20. Nieba, L., Krebber, A. and Plückthun, A. (1996) Competition BIAcore for measuring true affinities: Large differences from values determined from binding kinetics. Analyt. Biochem. 234, 155-165.
21. Nieto, A., Gaya, A., Jansa, M., Moreno, C. and Vives, J. (1984) Direct measurement of antibody affinity by hapten inhibition enzyme immunoassay. Mol. Immunol. 21, 537-543.
22. O'Shannessy, D.J. (1994) Determination of kinetic rate and equilibrium binding constants for macromolecular interactions: A critique of the surface plasmon resonance literature. Curr. Opin. Biotechnol. 5, 65-71.
23. O'Shannessy, D.J. and Winzor, D.J. (1996) Interpretation of deviation from pseudo-first-order kinetic behaviour in the characterisation of ligand binding by biosensor technology. Analyt. Biochem. 236, 275-283.
24. O'Shannessy, D.J., Brigham-Burke, M., Soneson, K.K., Hensley, P. and Brooks, I. (1993) Determination of rate and equilibrium binding constants for macromolecular interactions using surface plasmon resonance: Use of non-linear least squares analysis methods. Analyt. Biochem. 212, 457-468.
25. Piehler, J., Brecht, A., Kramer, K., Hock, B. and Gauglitz, G. (1995) Multi-analyte determination with an optical multi-antibody detection system. In: T. Vo-Dinh and R. Nießner (Eds.), Environmental Monitoring and Hazardous Waste Site Remediation. Proc. SPIE 2504, 185-193.
26. Piehler, J., Brecht, A. and Gauglitz, G. (1996) Surface modification for direct immunoprobes. Biosens. Bioelectron. 11, 579-590.
27. Portnoi, D., Freitas, A., Holmberg, D., Bandeira, A. and Coutinho, A. (1986) Immunocompetent autoreactive B lymphocytes are activated cycling cells in normal mice. J. Exp. Med. 164, 25-35.
28. Rath, S., Stanley, C.M. and Steward, M.W. (1988) An inhibition enzyme immunoassay for estimating relative antibody affinity and affinity heterogeneity. J. Immunol. Methods 106, 245-249.
29. Schots, A., Van der Leede, B.J., De Jongh, E. and Egberts, E. (1988) A method for the determination of antibody afffinity using a direct ELISA. J. Immunol. Methods 109, 225-233.
30. Seligman, S.J. (1994) Influence of solid phase antigen in competition enzyme-linked immunosorbent assays (ELISAs) on calculated antigen-antibody dissociation constants. J. Immunol. Methods 168, 101-110.
31. Stevens, F.J. (1987) Modification of an ELISA-based procedure for affinity determination: corrections necessary for use with bivalent antibody. Mol. Immunol. 24, 1055-1060.
32. Steward, M.W. and Lew, A.M. (1985) The importance of antibody affinity in the performance of immunoassays of antibody. J. Immunol. Methods 78, 173-190.
33. Steward, M.W. and Steengaard, J. (1983) Antibody Affinity: Thermodynamic Aspects and Biological Significance. CRC Press, Boca Raton, FL.
34. Ternynck, T. and Avrameas, S. (1986) Murine natural monoclonal antibodies - a study of their polyspecifities and their affinities. Immun. Rev. 94, 99-112.
35. Tijssen, P. (1985) Practice and Theory of Enzyme Immunoassay. Elsevier Science Publisher, Amsterdam.
36. Zierz, R. (1990) Herstellung immunreaktiver Fragmente aus monoklonalen Mausantikörpern, in: J.H. Peters and H. Baumgartner (Eds.), Monoklonale Antikörper, Herstellung und Charakterisierung. Springer Verlag, Heidelberg.