The Xenopus RNA polymerase I transcription factor, UBF, has a role in transcriptional enhancement distinct from that at the promoter

EMBO Journal

Volumn 16, Issue 2, 1997, Pages 396-405

  McStay, Brian ^a   Sullivan, Gareth J ^a   Cairns, Carol ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Enhancers; RNA polymerase I; UBF; Xenopus

Indexed keywords

BINDING PROTEIN; DNA DIRECTED RNA POLYMERASE; TATA BINDING PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SPECIES DIFFERENCE; TATA BOX; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; XENOPUS;

ANIMALS; CHROMATOGRAPHY, AFFINITY; DNA-BINDING PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENHANCER ELEMENTS (GENETICS); POL1 TRANSCRIPTION INITIATION COMPLEX PROTEINS; PROMOTER REGIONS (GENETICS); RESTRICTION MAPPING; RNA POLYMERASE I; TEMPLATES, GENETIC; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; XENOPUS; XENOPUS PROTEINS;

ANIMALIA; MAMMALIA;

EID: 0031027080     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.2.396     Document Type: Article

References (54)

1. Bachvarov, D. and Moss, T. (1991) The RNA polymerase I transcription factor xUBF contains 5 tandemly repeated HMG homology boxes. Nucleic Acids Res., 19, 2331-2335.
2. Bazett-Jones, D.P., Leblanc, B., Herfort, M. and Moss, T. (1994) Short-range DNA looping by the Xenopus HMG-box transcription factor, xUBF. Science, 264, 1134-1137.
3. Beckman, H., Chen, J.-L., O'Brien, T. and Tjian, R. (1995) Coactivator and promoter-selective properties of RNA polymerase I TAFs. Science, 270, 1506-1509.
4. Bell, S.P., Learned, R.M., Jantzen, H.-M. and Tjian, R. (1988) Functional cooperativity between transcription factors UBF1 and SL1 mediates human ribosomal RNA synthesis. Science, 241, 1192-1197.
5. Bell, S.P., Pikaard, C.S., Reeder, R.H. and Tjian, R. (1989) Molecular mechanisms governing species-specific transcription of ribosomal RNA. Cell, 59, 489-497.
6. Bodeker, M., Cairns, C. and McStay, B. (1996) Upstream binding factor stabilises Rib1, the TATA-binding-protein-containing Xenopus laevis RNA polymerase I transcription factor, by multiple protein interactions in a DNA-independent manner. Mol. Cell. Biol., 16, 5572-5578.
7. Busby, S.J. and Reeder, R.H. (1983) Spacer sequences regulate transcription of ribosomal gene plasmids injected into Xenopus embryos. Cell, 34, 989-996.
8. Cairns, C. and McStay, B. (1995) HMG box 4 is the principal determinant of species specificity in the RNA polymerase I transcription factor UBF. Nucleic Acids Res., 23, 4583-4590.
9. Chan, E.K., Imai, H., Hamel, J.C. and Tan, E.M. (1991) Human autoantibody to RNA polymerase I transcription factor hUBF. Molecular identity of nucleolus organizer region autoantigen NOR-90 and ribosomal RNA transcription upstream binding factor. J. Exp. Med., 174, 1239-1244.
10. Comai, L., Tanese, N. and Tjian, R. (1992) The TATA-binding protein and associated factors are integral components of the RNA polymerase I transcription factor, SL1. Cell, 68, 965-976.
11. Comai, L., Zomerdijk, J.C., Beckman, H., Zhou, S., Admon, A. and Tjian, R. (1994) Reconstitution of transcription factor SL1: exclusive binding of TBP by SL1 or TFIID subunits. Science, 266, 1966-1972.
12. Dignam, J.D., Martin, P.L., Shastry, B.S. and Roeder, R.G. (1983) Eukaryotic gene transcription with purified components. Methods Enzymol., 101, 582-598.
13. Du, W., Thanos, D. and Maniatis, T. (1993) Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements. Cell, 74, 887-898.
14. Dunaway, M. and Droge, P. (1989) Transactivation of the Xenopus rRNA gene promoter by its enhancer. Nature, 341, 657-659.
15. Eberhard, D., Tora, L., Egly, J.M. and Grummt, I. (1993) A TBP-containing multiprotein complex (TIP-IB) mediates transcription specificity of murine RNA polymerase I. Nucleic Acids Res., 21, 4180-4186.
16. Giese, K., Kingsley, C., Kirshner, J.R. and Grosschedl, R. (1995) Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions. Genes Dev., 9, 995-1008.
17. Goodrich, J.A. and Tjian, R. (1994) TBP-TAF complexes: selectivity factors for eukaryotic transcription. Curr. Opin. Cell. Biol., 6, 403-409.
18. Grosschedl, R., Giese, K. and Pagel, J. (1994) HMG domain proteins: architectural elements in the assembly of nucleoprotein structures. Trends Genet., 10, 94-100.
19. Hu, C.H., McStay, B., Jeong, S.W. and Reeder, R.H. (1994) xUBF, an RNA polymerase I transcription factor, binds crossover DNA with low-sequence specificity. Mol. Cell. Biol., 14, 2871-2882.
20. Jantzen, H.M., Admon, A., Bell, S.P. and Tjian, R. (1990) Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins. Nature, 344, 830-836.
21. Jantzen, H.M., Chow, A.M., King, D.S. and Tjian, R. (1992) Multiple domains of the RNA polymerase I activator hUBF interact with the TATA-binding protein complex hSL1 to mediate transcription. Genes Dev., 6, 1950-1963.
22. Kadonaga, J.T. and Tjian, R. (1986) Affinity purification of sequence-specific DNA binding proteins. Proc. Natl Acad. Sci. USA, 83, 5889-5893.
23. Kuhn, A., Deppert, U. and Grummt, I. (1990) A 140-base-pair repetitive sequence element in the mouse rRNA gene spacer enhances transcription by RNA polymerase I in a cell-free system. Proc. Natl Acad. Sci. USA, 87, 7527-7531.
24. Kuhn, A., Voit, R., Stefanovsky, V., Evers, R., Bianchi, M. and Grummt, I. (1994) Functional differences between the two splice variants of the nucleolar transcription factor UBF: the second HMG box determines specificity of DNA binding and transcriptional activity. EMBO J., 13, 416-424.
25. Kwon, H. and Green, M.R. (1994) The RNA polymerase I transcription factor, upstream binding factor, interacts directly with the TATA box-binding protein. J. Biol. Chem., 269, 30140-30146.
26. Labhart, P. and Reeder, R.H. (1984) Enhancer-like properties of the 60/81 bp elements in the ribosomal gene spacer of Xenopus laevis. Cell, 37, 285-289.
27. Labhart, P. and Reeder, R.H. (1985) Xenopus ribosomal gene enhancers function when inserted inside the gene they enhance. Nucleic Acids Res., 13, 8999-9009.
28. Labhart, P. and Reeder, R.H. (1986) Characterization of three sites of RNA 3′ end formation in the Xenopus ribosomal gene spacer. Cell, 45, 431-443.
29. McStay, B. and Reeder, R.H. (1986) A termination site for Xenopus RNA polymerase I also acts as an element of an adjacent promoter. Cell, 47, 913-920.
30. McStay, B. and Reeder, R.H. (1990) A DNA-binding protein is required for termination of transcription by RNA polymerase I in Xenopus laevis. Mol. Cell. Biol., 10, 2793-2800.
31. McStay, B., Hu, C.-H., Pikaard, C.S. and Reeder, R.H. (1991a) xUBF and Rib 1 are both required for formation of a stable polymerase I promoter complex in X.laevis. EMBO J., 10, 2297-2303.
32. McStay, B., Frazier, M.W. and Reeder, R.H. (1991b) xUBF contains a novel dimerization domain essential for RNA polymerase I transcription. Genes Dev., 5, 1957-1968.
33. Mishima, Y., Financsek, I., Kominami, R. and Muramatsu, M. (1982) Fractionation and reconstitution of factors required for accurate transcription of mammalian ribosomal RNA genes: identification of a species-dependent initiation factor. Nucleic Acids Res., 10, 6659-6670
34. Moss, T. (1983) A transcriptional function for the repetitive ribosomal spacer in Xenopus laevis. Nature, 302, 223-228.
35. O'Mahony, D.J. and Rothblum, L.I. (1991) Identification of two forms of the RNA polymerase I transcription factor UBF. Proc. Natl Acad. Sci. USA, 88, 3180-3184.
36. Osheim, Y.N., Mougey, E.B., Windle, J., Anderson, M., O'Rielly, M., Miller, O.L., Beyer, A. and Sollner-Webb, B. (1996) Metazoan rDNA enhancer acts by making more genes transcriptionally active. J. Cell Biol., 133, 943-954.
37. Pikaard, C.S. (1994) Ribosomal gene promoter domains can function as artificial enhancers of RNA polymerase I transcription, supporting a promoter origin for natural enhancers in Xenopus. Proc. Natl Acad. Sci. USA, 91, 464-468.
38. Pikaard, C.S., Pape, L.K., Henderson, S.L. Ryan, K., Paalman, M.H., Lopata, A., Reeder, R.H. and Sollner-Webb, B. (1990) Enhancers for RNA polymerase I in mouse ribosomal DNA. Mol. Cell. Biol., 10, 4816-4825.
39. Putnam, C.D., Copenhaver, G.P., Denton, M.L. and Pikaard, C.S. (1994) The RNA polymerase I transactivator upstream binding factor requires its dimerization domain and high-mobility-group (HMG) box 1 to bend, wrap, and positively supercoil enhancer DNA. Mol. Cell. Biol., 14, 6476-6488.
40. Putnam, C.D. and Pikaard, C.S. (1992) Cooperative binding of the Xenopus RNA polymerase I transcription factor xUBF to repetitive ribosomal gene enhancers. Mol. Cell. Biol., 12, 4970-4980.
41. Reeder, R.H. (1992) The regulation of transcription by RNA polymerase I. In McKnight, S.L. and Yamamoto, K. (eds), Transcriptional Regulation. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 315-347.
42. Reeder, R.H., Roan, J.G. and Dunaway, M. (1983) Spacer regulation of Xenopus ribosomal gene transcription: competition in oocytes. Cell, 35, 449-456.
43. Reeder, R.H., Pikaard, C.S. and McStay, B. (1995) UBF, an architectural element for RNA polymerase I promoters. In Eckstein, F. and Lilley, D.M.J. (eds), Nucleic Acids and Molecular Biology. Springer-Verlag, Berlin, Heidelberg, Vol. 9, pp. 251-263.
44. Sauer, F., Hansen, S.K. and Tjian, R. (1995a) Multiple TAFIIs directing synergistic activation of transcription. Science, 270, 1783-1788.
45. Sauer, F., Hansen, S.K. and Tjian, R. (1995b) DNA template and activator-coactivator requirements for transcriptional synergism by Drosophila bicoid. Science, 270, 1825-1828.
46. Schnapp, A., Clos, J., Hadelt, W., Schreck, R., Cvekl, A. and Grummt, I. (1990) Isolation and functional characterization of TIF-IB, a factor that confers promoter specificity to mouse RNA polymerase I. Nucleic Acids Res., 18, 1385-1393.
47. Schultz, M.C., Choe, S.Y. and Reeder, R.H. (1993) In vitro definition of the yeast RNA polymerase I enhancer. Mol. Cell. Biol., 13, 2644-2654.
48. Stefanovsky, V.Y., Bazett-Jones, D.P., Pelletier, G, and Moss, T. (1996) The DNA supercoiling architecture induced by the transcription factor xUBF requires three of its five HMG-boxes. Nucleic Acids Res., 24, 3208-3215.
49. Thanos, D. and Maniatis, T. (1992) The high mobility group protein HMG I(Y) is required for NF-kappa B-dependent virus induction of the human IFN-beta gene. Cell, 71, 777-789.
50. Tjian, R. and Maniatis, T. (1994) Transcriptional activation: a complex puzzle with few easy pieces. Cell, 77, 5-8.
51. Tower, J., Culotta, V.C. and Sollner-Webb, B. (1986) Factors and nucleotide sequences that direct ribosomal DNA transcription and their relationship to the stable transcription complex. Mol. Cell. Biol., 6, 3451-3462.
52. Walters, M.C., Fiering, S., Eidemiller, J., Magis, W., Groudine, M. and Martin, D.I. (1995) Enhancers increase the probability but not the level of gene expression. Proc. Natl Acad. Sci. USA, 92, 7125-7129.
53. Walters, M.C., Magis, W., Fiering, S., Eidemiller, J., Scalzo, D., Groudine, M. and Martin, D.I. (1996) Transcriptional enhancers act in cis to suppress position-effect variegation. Genes Dev., 10, 185-195.
54. Zomerdijk, J.C., Beckman, H., Comai, L. and Tjian, R. (1994) Assembly of transcriptionally active RNA polymerase I initiation factor SL1 from recombinant subunits. Science, 266, 2015-2018.