Simulation models to predict oral drug absorption from in vitro data

Advanced Drug Delivery Reviews

Volumn 23, Issue 1-3, 1997, Pages 199-219

  Grass, George M ^a  

^a Precision Instrument Design Inc   (United States)

Author keywords

in vitro; intestine; oral absorption model; permeability; prediction; simulation; solubility; STELLA

Indexed keywords

ABSORPTION; CELL CULTURE; CELLS; COMPUTER SIMULATION; DRUG PRODUCTS; MATHEMATICAL MODELS; SOLUBILITY; TISSUE;

INTESTINE; ORAL DRUG ABSORPTION;

DRUG THERAPY;

ACETYLSALICYLIC ACID; CEFALEXIN; CEFATRIZINE; CEFUROXIME; CIMETIDINE; FUROSEMIDE; GANCICLOVIR; HYDROCORTISONE; LIXAZINONE; MACROGOL; MACROGOL 4000; MANNITOL; METHANOL; METHOXYINULIN; METHYLDOPA; NAPROXEN; PENICILLIN V; PREDNISOLONE; PROGESTERONE; UNCLASSIFIED DRUG;

ANIMAL MODEL; CELL CULTURE; COMPARTMENT MODEL; COMPUTER SIMULATION; DRUG ABSORPTION; DRUG DEGRADATION; DRUG DEVELOPMENT; DRUG METABOLISM; DRUG SOLUBILITY; HUMAN; INTESTINE ABSORPTION; MODEL; NONHUMAN; ORAL DRUG ADMINISTRATION; PH; PREDICTION; PRIORITY JOURNAL; REVIEW;

EID: 0031026707     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(96)00436-X     Document Type: Review

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