메뉴 건너뛰기




Volumn 34, Issue 1, 1997, Pages 39-42

Germline HNPCC gene variants have little influence on the risk for sporadic colorectal cancer

Author keywords

Early onset sporadic colon cancer; HNPCC

Indexed keywords

ADULT; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CLINICAL ARTICLE; COLORECTAL CANCER; DNA POLYMORPHISM; DNA REPAIR; FAMILIAL CANCER; FAMILY HISTORY; GENE LOCUS; GENE MUTATION; GENETIC SCREENING; GERM LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; MASS SCREENING; PREVALENCE; PRIORITY JOURNAL;

EID: 0031025987     PISSN: 00222593     EISSN: None     Source Type: Journal    
DOI: 10.1136/jmg.34.1.39     Document Type: Article
Times cited : (34)

References (20)
  • 1
    • 0007891207 scopus 로고
    • Molecular genetics of colon cancer
    • Cowell JK, ed. Oxford: BIOS Scientific Publications
    • Dunlop MG. Molecular genetics of colon cancer. In: Cowell JK, ed. The molecular genetics of cancer. Oxford: BIOS Scientific Publications, 1995:113-34.
    • (1995) The Molecular Genetics of Cancer , pp. 113-134
    • Dunlop, M.G.1
  • 2
    • 0027742295 scopus 로고
    • The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
    • Fishel R, Lescoe MK, Rao MR, et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 1993;75:1027-38.
    • (1993) Cell , vol.75 , pp. 1027-1038
    • Fishel, R.1    Lescoe, M.K.2    Rao, M.R.3
  • 3
    • 0027145633 scopus 로고
    • Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
    • Leach FS, Nicolaides NC, Papadopoulos N, et al. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 1993;75:1215-25.
    • (1993) Cell , vol.75 , pp. 1215-1225
    • Leach, F.S.1    Nicolaides, N.C.2    Papadopoulos, N.3
  • 4
    • 0027933070 scopus 로고
    • Mutations of two PMS homologues in hereditary nonpolyposis colon cancer
    • Nicolaides NC, Papadopoulos N, Liu B, et al. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature 1994;371:75-80.
    • (1994) Nature , vol.371 , pp. 75-80
    • Nicolaides, N.C.1    Papadopoulos, N.2    Liu, B.3
  • 5
    • 0028350601 scopus 로고
    • Mutation of a mutL homolog in hereditary colon cancer
    • Papadopoulos N, Nicolaides NC, Wei YF, et al. Mutation of a mutL homolog in hereditary colon cancer. Science 1994;263:1625-9.
    • (1994) Science , vol.263 , pp. 1625-1629
    • Papadopoulos, N.1    Nicolaides, N.C.2    Wei, Y.F.3
  • 6
    • 0025082951 scopus 로고
    • Screening and genetic counselling for relatives of patients with colorectal cancer in a family cancer clinic
    • Houlston RS, Murday V, Harocopos C, Williams CB, Slack J. Screening and genetic counselling for relatives of patients with colorectal cancer in a family cancer clinic. BMJ 1990; 301:366-8.
    • (1990) BMJ , vol.301 , pp. 366-368
    • Houlston, R.S.1    Murday, V.2    Harocopos, C.3    Williams, C.B.4    Slack, J.5
  • 7
    • 0028330276 scopus 로고
    • Risks of cancer in BRCA1-mutation carriers. Breast Cancer Linkage Consortium
    • Ford D, Easton DF, Bishop DT, Narod SA, Goldgar DE. Risks of cancer in BRCA1-mutation carriers. Breast Cancer Linkage Consortium. Lancet 1994;343:692-5.
    • (1994) Lancet , vol.343 , pp. 692-695
    • Ford, D.1    Easton, D.F.2    Bishop, D.T.3    Narod, S.A.4    Goldgar, D.E.5
  • 8
    • 0028859671 scopus 로고
    • Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability
    • Liu B, Nicolaides NC, Markowitz S, et al. Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability. Nat Genet 1995;9:48-55.
    • (1995) Nat Genet , vol.9 , pp. 48-55
    • Liu, B.1    Nicolaides, N.C.2    Markowitz, S.3
  • 9
    • 0029983118 scopus 로고    scopus 로고
    • MSH2 sequence variations and inherited colorectal-cancer susceptibility
    • Froggatt NJ, Joyce JA, Evans DGR, et al. MSH2 sequence variations and inherited colorectal-cancer susceptibility. Eur J Cancer 1996;32:178.
    • (1996) Eur J Cancer , vol.32 , pp. 178
    • Froggatt, N.J.1    Joyce, J.A.2    Evans, D.G.R.3
  • 10
    • 2942569549 scopus 로고    scopus 로고
    • Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients
    • Liu B, Parsons R, Papadopoulos N, et al. Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients. Nat Med 1996;2:169-74.
    • (1996) Nat Med , vol.2 , pp. 169-174
    • Liu, B.1    Parsons, R.2    Papadopoulos, N.3
  • 11
    • 0028915223 scopus 로고
    • Genetic instability occurs in the majority of young patients with colorectal cancer
    • Liu B, Farrington SM, Petersen GM, et al. Genetic instability occurs in the majority of young patients with colorectal cancer. Nat Med 1995;1:348-52.
    • (1995) Nat Med , vol.1 , pp. 348-352
    • Liu, B.1    Farrington, S.M.2    Petersen, G.M.3
  • 12
    • 0028916112 scopus 로고
    • A rapid method for detection of mutations in the lacI gene using PCR-single strand conformation polymorphism analysis: Demonstration of its high sensitivity
    • Ushijima T, Hosoya Y, Suzuki T, Sofuni T, Sugimura T, Nagao M. A rapid method for detection of mutations in the lacI gene using PCR-single strand conformation polymorphism analysis: demonstration of its high sensitivity. Mutat Res 1995;334:283-92.
    • (1995) Mutat Res , vol.334 , pp. 283-292
    • Ushijima, T.1    Hosoya, Y.2    Suzuki, T.3    Sofuni, T.4    Sugimura, T.5    Nagao, M.6
  • 13
    • 0028198386 scopus 로고
    • Sensitivity of single-strand conformation polymorphism and heteroduplex method for mutation detection in the cystic fibrosis gene
    • Ravnik GM, Glavac D, Dean M. Sensitivity of single-strand conformation polymorphism and heteroduplex method for mutation detection in the cystic fibrosis gene. Hum Mol Genet 1994;3:801-7.
    • (1994) Hum Mol Genet , vol.3 , pp. 801-807
    • Ravnik, G.M.1    Glavac, D.2    Dean, M.3
  • 14
    • 0027982001 scopus 로고
    • Comparative sensitivity of alternative single-strand conformation polymorphism (SSCP) methods
    • Vidai PA, Moller DE. Comparative sensitivity of alternative single-strand conformation polymorphism (SSCP) methods. Biotechniques 1994;17:490-2.
    • (1994) Biotechniques , vol.17 , pp. 490-492
    • Vidai, P.A.1    Moller, D.E.2
  • 15
    • 0027193630 scopus 로고
    • The sensitivity of single-strand conformation poly-morphism analysis for the detection of single base substitutions
    • Sheffield VC, Beck JS, Kwitek AE, Sandstrom DW, Stone EM. The sensitivity of single-strand conformation poly-morphism analysis for the detection of single base substitutions. Genomics 1993;16:325-32.
    • (1993) Genomics , vol.16 , pp. 325-332
    • Sheffield, V.C.1    Beck, J.S.2    Kwitek, A.E.3    Sandstrom, D.W.4    Stone, E.M.5
  • 16
    • 0029897836 scopus 로고    scopus 로고
    • Attenuated familial adenomatous polyposis due to a mutation in the 3′ part of the APC gene. A clue for understanding the function of the APC protein
    • Friedl W, Meuschel S, Caspari R, et al. Attenuated familial adenomatous polyposis due to a mutation in the 3′ part of the APC gene. A clue for understanding the function of the APC protein. Hum Genet 1996;97:579-84.
    • (1996) Hum Genet , vol.97 , pp. 579-584
    • Friedl, W.1    Meuschel, S.2    Caspari, R.3
  • 17
    • 0027724691 scopus 로고
    • Alleles of the APC gene: An attenuated form of familial polyposis
    • Spirio L, Olschwang S, Groden J, et al. Alleles of the APC gene: an attenuated form of familial polyposis. Cell 1993; 75:951-7.
    • (1993) Cell , vol.75 , pp. 951-957
    • Spirio, L.1    Olschwang, S.2    Groden, J.3
  • 18
    • 0029915034 scopus 로고    scopus 로고
    • Overview of natural history, pathology, molecular genetics and management of HNPCC (Lynch syndrome)
    • Lynch HT, Smyrk T, Lynch JF. Overview of natural history, pathology, molecular genetics and management of HNPCC (Lynch syndrome). Int J Cancer 1996;69:38-43.
    • (1996) Int J Cancer , vol.69 , pp. 38-43
    • Lynch, H.T.1    Smyrk, T.2    Lynch, J.F.3
  • 20
    • 0030063728 scopus 로고    scopus 로고
    • Are we any closer to genetic testing for common malignancies?
    • Plummer SJ, Casey G. Are we any closer to genetic testing for common malignancies? Nat Med 1996;2:156-8
    • (1996) Nat Med , vol.2 , pp. 156-158
    • Plummer, S.J.1    Casey, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.