Purkinje cell loss in heterozygous staggerer mutant mice during aging

Developmental Brain Research

Volumn 98, Issue 1, 1997, Pages 1-8

  Hadj Sahraoui, Nadia ^a   Frederic, Florence ^a   Zanjani, Hadi ^a   Herrup, Karl ^b   Delhaye Bouchaud, Nicole ^a   Mariani, Jean ^a  

^a CNRS   (France)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

aging; cerebellum; heterozygous staggerer; mutant mouse; Purkinje cells

Indexed keywords

AGING; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LOSS; CEREBELLUM; CONTROLLED STUDY; FEMALE; HISTOLOGY; IMMUNOCYTOCHEMISTRY; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL;

AGE DISTRIBUTION; AGING; ANIMALS; CALCIUM-BINDING PROTEIN, VITAMIN D-DEPENDENT; CELL COUNT; FEMALE; GENOTYPE; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; MICE, NEUROLOGIC MUTANTS; NERVE TISSUE PROTEINS; PURKINJE CELLS;

EID: 0031025770     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-3806(96)00153-8     Document Type: Article

References (37)

1. Ramon y Cajal, S. (1911) Histologie du Système Nerveux de l'Homme et des Vertébrés, Masson, Paris.
2. Blatt, G.J. and Eisenman, L.M. (1985) A qualitative and quantitative light microscopic study of the inferior olivary complex in the adult staggerer mutant mouse, J. Neurogenet., 2, 51-66.
3. Bradley, P. and Berry, M. (1978) Purkinje cell dendritic tree in mutant mouse cerebellum. A quantitative Golgi study of weaver and staggerer mice, Brain Res., 142, 135-141.
4. Crepel, F. and Mariani, J. (1975) Anatomical, physiological and biochemical studies of the cerebellum from mutant mice. I. Electro-physiological analysis of cerebellar neurons in the staggerer mouse, Brain Res., 98, 135-147.
5. Herrup, K. and Mullen, R.J. (1979) Regional variation and absence of large neurons in the cerebellum of the staggerer mouse, Brain Res., 172, 1-12.
6. Hirano, A. and Dembitzer, H.M. (1975) The fine structure of the staggerer cerebellum, J. Neuropath. Exp. Neurol., 34, 1-11.
7. Sidman, R.W., Lane, P.W. and Dickie, M.N. (1962) Staggerer, a new mutation in the mouse affecting the cerebellum, Science, 137, 610-612.
8. Herrup, K. and Mullen, R.J. (1981) Role of the staggerer gene in determining Purkinje cell number in the cerebellar cortex of mouse chimeras, Dev. Brain Res., 1, 475-485.
9. Herrup, K. (1983) Role of staggerer gene in determining cell number in cerebellar cortex. I. Granule cell death is an indirect consequence of staggerer gene action, Dev. Brain Res., 11, 267-274.
10. Zanjani, H.S., Mariani, J. and Herrup, K. (1990) Cell loss in the inferior olive of the staggerer mutation mouse is an indirect effect of the gene, J. Neurogenet., 6, 229-241.
11. Hamilton, B.A., Frankel, W.N., Kerrebrock, A.W., Hawkins, T.L., Fitzhugh, W., Kusumi, K., Russel, L.B., Mueller, K.L., Berkel, V.V., Birren, B.W., Kruglyak, L. and Lander, E.S. (1996) Disruption of the nuclear hormone receptor RORα in staggerer mice, Nature, 379, 736-739.
12. Shojaeian-Zanjani, H., Mariani, J., Delhaye-Bouchaud, N. and Herrup, K. (1992) Neuronal cell loss in heterozygous staggerer mutant mice: a model for genetic contributions to the aging process, Dev. Brain Res., 67, 153-160.
13. Bakalian, A., Corman, B., Delhaye-Bouchaud, N. and Mariani, J. (1990) Quantitative analysis of the Purkinje cell population during extreme ageing in the cerebellum of the Wistar/Louvain rat, Neurobiol. Aging, 12, 425-430.
14. Caddy, K.W.T. and Biscoe, T.J. (1979) Structural and quantitative studies on the normal C3H and 'Lurcher' mutant mouse, Phil. Trans. R. Soc. Lond. Ser. B, 287, 167-201.
15. Ellis, R.S. (1919) A preliminary quantitative study of the Purkinje cells in normal, subnormal and senescent human cerebella, with some notes on functional localization, J. Comp. Neurol., 30, 229-252.
16. Ellis, R.S. (1920) Norms for some structural changes in the human cerebella from birth to old age, J. Comp. Neurol, 32, 1-32.
17. Hall, T.C., Miller, A.K.H. and Corsellis, J.A.N. (1975) Variations in the human Purkinje cell population according to age and sex, Neuropathol. Appl. Neurobiol., 1, 267-292.
18. Hinukai, T. (1928) On the cell loss of Purkinje cells, with advancing age, from the cerebellar cortex of the Albino rat, J. Comp. Neurol., 45, 1-31.
19. Nandy, K. (1981) Morphological changes in the cerebellar cortex of aging Macaca nemestrina, Neurobiol. Aging, 2, 61-64.
20. Rogers, J., Silver, M.A., Shoemaker, W.J. and Bloom, F.E. (1980) Senescent changes in a neurobiological model system: cerebellar Purkinje cell electrophysiology and correlative anatomy, Neurobiol. Aging, 1, 3-11.
21. Sturrock, R.R. (1989) Changes in neuron number in the cerebellar cortex of the aging mouse, Z. Hirnforsch., 30, 499-503.
22. Bakalian, A., Delhaye-Bouchaud, N. and Mariani, J. (1995) Quantitative analysis of the Purkinje cell and the granule cell populations in the cerebellum of nude mice, J. Neurogenet., 9, 207-218.
23. Wetts, R. and Herrup, K. (1982) Interaction of granule, Purkinje and inferior olivary neurons in lurcher chimeric mice. I. Qualitative studies, J. Embryol. Exp. Morphol., 68, 87-98.
24. Wetts, R. and Herrup, K. (1982) Interaction of granule, Purkinje and inferior olivary neurons in lurcher chimeric mice. II. Granule cell death, Brain Res., 250, 358-362.
25. Hendry, I.A. (1976) A method to correct adequately for the change in neuronal size when estimating neuronal numbers after nerve growth factor treatment, J. Neurocytol., 5, 337-349.
26. Legrand, C., Thomasset, M., Parkes, C.O., Clavel, M.C. and Rabié, A. (1983) Calcium-binding protein in the developing rat cerebellum, Cell Tissue Res., 233, 389-402.
27. Hadj-Sahraoui, N., Frederic, F., Delhaye-Bouchaud, N. and Mariani, J. (1996) Gender effect on Purkinje cell loss in the cerebellum of the heterozygous reeler mouse ( + /rl), J. Neurogenet., in press.
28. Boegman, R., Parent, A. and Hawkes, R. (1988) Zonation in the rat cerebellar cortex: patches of high acetylcholinesterase activity in the granular layer are congruent with Purkinje cell compartments, Brain Res., 448, 237-251.
29. Eisenman, L.M. and Hawkes, R. (1990) 5′-Nucleotidase and the mabQ113 antigen share a common distribution in the cerebellar cortex of the mouse, Neuroscience, 31, 231-235.
30. Eisenman, L.M. and Hawkes, R. (1993) Antigenic compartmentation in the mouse cerebellar cortex: Zebrin and HNK-1 reveal a complex, overlapping molecular topography, J. Comp. Neural., 335, 586-605.
31. Leclerc, N., Schwarting, G.A., Herrup, K., Hawkes, R. and Yamamoto, M. (1992) Compartmentation in mammalian cerebellum: Zebrin II and P-path define three classes of Purkinje cells, Proc. Natl. Acad. Sci. USA, 89, 5006-5010.
32. Oberdick, J., Schilling, K., Smeyne, R.J., Corbin, J.G., Bocchiaro, C. and Morgan, J.I. (1993) Control of segment-like patterns of gene expression in cerebellar Purkinje and retinal bipolar neurons, Neuron, 10, 1007-1018.
33. Wassef, M., Sotelo, C. and Thomasset, M. (1990) Expression of compartmentation antigen Zebrin I in cerebellar transplants, J. Comp. Neurol., 294, 223-234.
34. Hadj-Sahraoui, N., Zanjani, H.S., Frederic, F., Delhaye-Bouchaud, N., Herrup, K. and Mariani, J. (1995) Quantitative analysis of the cerebellar Purkinje cells during aging of the heterozygous staggerer mouse, Neurosci. Abstr., 21, pp. 1563.
35. Gaston, J., Delhaye-Bouchaud, N. and Mariani, J. (1996) Motor behavior of heterozygous staggerer mutant ( + /sg) versus normal ( + / + ) mice during ageing, Behav. Brain Res., 72, 97-102.
36. Woodruff-Pak, D.S., Cronholm J.F. and Sheffield, J.B. (1990) Purkinje cell number related to rate of classical conditioning, NeuroReport, 1, 165-168.
37. Taylor, B.A. (1972) Genetic relationships between inbred strains of mice, J. Hered., 63, 83-86.