Concurrent treatment of nonresistant major depression with desipramine and lithium: A double-blind, placebo-controlled study

Journal of Clinical Psychopharmacology

Volumn 17, Issue 1, 1997, Pages 44-48

  Bloch, Miki ^a,c   Schwartzman, Yacob ^b   Bonne, Omer ^a   Lerer, Bernard ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b Jerusalem Mental Health Center Ezrath Nashim   (Israel)

^c NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DESIPRAMINE; LITHIUM; LITHIUM CARBONATE; PLACEBO;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DOUBLE BLIND PROCEDURE; DRUG COMBINATION; DRUG ERUPTION; FEMALE; HUMAN; MALE; MULTICENTER STUDY; PRIORITY JOURNAL; SOMNOLENCE; SWEATING; TREMOR; URINE RETENTION; VERTIGO; XEROSTOMIA;

ADULT; AGED; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BIPOLAR DISORDER; DEPRESSIVE DISORDER; DESIPRAMINE; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; LITHIUM CARBONATE; MALE; MIDDLE AGED; PSYCHIATRIC STATUS RATING SCALES; TREATMENT OUTCOME;

EID: 0031025698     PISSN: 02710749     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004714-199702000-00008     Document Type: Article

References (32)

1. Quitkin FM, Rabkin JG, Ross D, McGrath PJ. Duration of AD drug treatment. What is an adequate trial? Arch Gen Psychiatry 1984; 41:238-45.
2. Stockmeier CA, Martino AM, Keller KJ. A strong influence of serotonergic axons on beta-adrenergic receptors in rat brain. Science 1985;230:323-5.
3. Brunello N, Baraccia ML, Chuang D-M, Costa E. Down-regulation of beta-adrenergic receptors following repeated injections of desmethylimipramine: permissive role of serotonergic axons. Neuropharmacology 1982;21:1145-9.
4. Baron BM, Ogden AM, Siegel BW, Stegeman J, Ursillo RC, Dudley MW. Rapid down-regulation of beta-adrenoreceptors by co-administration of DMI and fluoxetine. Eur J Pharmacol 1988;154: 125-34.
5. Nelson JC, Mazure CM, Bowers MB, Jatlow PI. A preliminary, open study of the combination of fluoxetine and DMI for rapid treatment of major depression. Arch Gen Psychiatry 1991;448: 303-7.
6. De Montigny C, Cournoyer G, Morissette R, Langlois R, Caille G. Li carbonate addition in tricyclic AD-resistant unipolar depression. Arch Gen Psychiatry 1983;40:1327-34.
7. Heninger GR, Chamey DS, Sternberg DE. Li carbonate augmentation of AD treatment. Arch Gen Psychiatry 1983;40:1335-42.
8. Schopf J, Baumann P, Lemarchand T, Rey M. Treatment of endogenous depression resistant to tricyclic ADs or related drugs by Li addition. Results of a placebo-controlled double-blind study. Pharmacopsychiatry 1989;22:183-7.
9. Nierenberg AA. Treatment choice after one AD fails: a survey of northeastern psychiatrists. J Clin Psychiatry 1991;52:383-5.
10. Price LH, Charney DS, Heninger GR. Variability of response to Li augmentation in refractory depression. Am J Psychiatry 1986; 143:1387-92.
11. Zall H, Therman PG, Myers JM. Li carbonate: a clinical study. Am J Psychiatry 1968;125:549-55.
12. Zall H. Li carbonate and isocarboxazid - an effective drug approach in severe depressions. Am J Psychiatry 1971;127:1400-3.
13. Lingjaerde O, Edlund AH, Gormsen CA, Gottfries CG, Haugstad A, Hermann IL, Hollnagel P, Makimattila A, Rasmussen KE, Remvig J, Robak OH. The effect of Li carbonate in combination with tricyclic ADs in endogenous depression. Acta Psychiatr Scand 1974;50:233-42.
14. Austin LS, Arana GW, Ballenger JC. Rapid response of patients simultaneously treated with Li and nortriptyline. J Clin Psychiatry 1990;51:124-5.
15. Schopf J. Treatment of depression resistant to tricyclic ADs, related drugs or MAO-inhibitors by Li addition: review of the literature. Pharmacopsychiatry 1989;22:174-82.
16. Sackeim HA, Prudic J, Devanand DP, Decina P, Kerr B, Malitz S. The impact of medication resistance and continuation pharmacotherapy on relapse following response to electroconvulsive therapy in major depression. J Clin Psychopharmacol 1990;10: 96-104.
17. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960;23:56-62.
18. Nelson JC, Jatlow PL, Quinlan DM, Bowers MB Jr. DMI plasma concentration and AD response. Arch Gen Psychiatry 1982;39: 1419-22.
19. Stein G, Bernadt M. Li augmentation therapy in tricyclic-resistant depression. A controlled trial using Li in low and normal doses. Br J Psychiatry 1993;162:634-40.
20. Guy W. ECDEU assessment manual for psychopharmacology. Rockville, MD: NIMH, 1976:218-22.
21. Aifken RCB. Measurement of feelings using visual analogue scales. Proc R Soc Med 1969;62:989-93.
22. Cohen J. Statistical power analysis for the behavioral sciences. 2nd ed. Hillsdale, NJ: Lawrence Erlbaum Associates, 1988.
23. Ebert D, Jaspert A, Murata H, Kaschka P. Initial Li augmentation improves the AD effects of standard TCA treatment in non-resistant depressed patients. Psychopharmacology 1995;118:223-5.
24. Nick J, Luaute JP, des Lauriers A, Moinet A, Monfort J. L' association clomipramine-lithium, essai controle. Encephale 1976;2:5-16.
25. Joffe RT, Singer W, Levitt AJ, MacDonald C. A placebo-controlled comparison of Li and triiodothyronine augmentation of tricyclic ADs in unipolar refractory depression. Arch Gen Psychiatry 1993; 50:387-93.
26. Cournoyer G, de Montigny C, Ouellette J, Leblanc G, Langois R, Elie R. Li addition in tricyclic-resistant unipolar depression: a placebo-controlled study [abstract]. Coll Int Neuro-Psychopharmacol 1983;14:F-177.
27. Zusky PM, Biederman J, Rosenbaum JF, Manschreck TC, Gross CC, Weilberg JB, Gastfriend DR. Adjunct low dose Li carbonate in treatment-resistant depressant: a placebo-controlled study. J Clin Psychopharmacol 1988;8:120-4.
28. Ontiveros A, Fontaine R, Elie R. Refractory depression: the addition of Li to fluoxetine or DMI. Acta Psychiatr Scand 1991;83: 188-92.
29. Schou M. Li in psychiatric therapy and prophylaxis. J Psychiatr Res 1968;5:67-95.
30. Goodwin FK, Murphy DL, Bunney WE. Li carbonate treatment in depression and mania: a longitudinal double-blind study. Arch Gen Psychiatry 1969;21:486-96.
31. Mendels J. Li in the treatment of depression. Am J Psychiatry 1976;133:373-8.
32. Susler F. Serotonin-norepinephrine receptor interactions in the brain: implication for the pharmacology and pathophysiology of affective disorders. J Clin Psychiatry 1987;48[suppl 3]: 12-8.