Lymphocyte Activation Markers in Peripheral Blood before and after Natural Exposure to Allergen in Asthmatic Patients

Respiration

Volumn 64, Issue 1, 1997, Pages 45-49

  Majori, Maria ^a   Piccoli, Laura ^a   Melej, Roberto ^b   Pileggi, Vincenzo ^c   Pesci, Alberto ^a  

^a Istituto di Clinica delle Malattie dell'Apparato Respiratorio dell'Universit di Parma   (Italy)

^b USL 4   (Italy)

^c Divisione di Medicina   (Italy)

Author keywords

Allergen exposure; Asthma; Flow cytometry; Peripheral blood lymphocytes

Indexed keywords

ALLERGEN; CYTOKINE; IMMUNOGLOBULIN E; METHACHOLINE;

ADULT; ALLERGIC ASTHMA; ANTIGEN EXPRESSION; ARTICLE; ASTHMA; B LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; GRASS POLLEN; HUMAN; LYMPHOCYTE ACTIVATION; MALE; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROVOCATION TEST; SEASON; T LYMPHOCYTE SUBPOPULATION;

ADULT; ALLERGENS; ANTIGENS, CD; ASTHMA; B-LYMPHOCYTES; BIOLOGICAL MARKERS; CD4-CD8 RATIO; ENVIRONMENTAL EXPOSURE; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOPHENOTYPING; LYMPHOCYTE ACTIVATION; MALE; POACEAE; POLLEN; T-LYMPHOCYTES;

EID: 0031025598     PISSN: 00257931     EISSN: 14230356     Source Type: Journal    
DOI: 10.1159/000196641     Document Type: Article

References (19)

1. Cantrell DA, Smith KA: Transient expression of interleukin-2 receptors, Consequences for T cell growth, J Exp Med 1983:158:1895-1911.
2. Reinherz EL, Rung PC, Pesando JM, Ritz J, Goldstein G, Schlossntan SF: la determinants on human T-cell subsets defined by monoclonal antibodies, Activation stimuli required for expression, J Exp Med 1979:150:1472-1482.
3. Hemler ME, Jacobson JG, Brenner MB, Mann D, Strominger JL: VLA-1: A T-ccll surface antigen which defines a novel late stage of human T-ccll activation, Eur J Immunol 1985:15:502- 508.
4. Corrigan CJ, Hartnell A, Kay AB: T lymphocyte activation in acute severe asthma, Lancet 1988.1:1129-1132.
5. Corrigan CJ, Haczku A, Gemou-Engcsacth V, Doi S, Kikuchi Y, Takatsu K, Durham SR, Kay AB: CD4 T-lymphocyte activation in asthma is accompanied by increased serum concentrations of interleukin-5, Effect of glucocorticoid therapy, Am Rev Rcspir Dis 1993; 147:540- 547.
6. Azzawi M, Bradley B, Jeffery PK, Frew AJ, Wardlaw AJ, Knowles G, Assoufi B, Collins JV, Durham S, Kay AB: Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma, Am Rev RespirDis 1990;142:1407-1413.
7. Wilson JW, Djukanovic R, Howarth PH, Hol-gate ST: Lymphocyte activation in bronchoal-veolar lavage and peripheral blood in atopic asthma, Am Rev Respir Dis 1992; 145:958- 960.
8. Rawle FC, Mitchell EB, Platls-Mills TA: T cell responses to the major allergen from the house dust miteDennalophagoides pteronyssinus, Antigen PI: Comparison of patients with asthma, atopic dermatitis, and perennial rhinitis, J Immunol 1984:133:195-201.
9. Gcrblich AA, Salik H, Schuyler MR: Dynamic T-ccll changes in peripheral blood and bron-choalvcolar lavage after antigen bronehopro-vocation in asthmatics, Am Rev Respir Dis 1991;143:533-537.
10. American Thoracic Society: Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma, Am Rev Respir Dis 1987:136:225- 244.
11. Gerblich AA, Campbell AW, Schuyler MR: Changes in T-lvmphocyte subpopulations after antigenic bronchial provocation in asthmatics, NEngl J Med 1984;310:1349-1352.
12. Bellini A, Vittori E, Marini M, Ackerman V, Mattoli S: Intraepithelial dendritic cells and selective activation of TH2-like lymphocytes in patients with atopic asthma, Chest 1993: 103:997-1005.
13. Daniele RP: Pathophysiology of the asthmatic syndromes: in Daniele RP (ed): Immunologic Diseases of the Lung, Boston, Blackwell Scientific, 1988, pp 503-516.
14. Walker C, Bode E, Boer L, Hansel TT, Blaser K, Virchow JC: Allergic and nonallergic asthmatics have distinct patterns of T-ccll activation and cytokine production in peripheral blood and bronchoalveolar lavage, Am Rev RespirDis 1992;146:109-115.
15. Corominas M, Meslrc M, Bas J, Verdaguer J, Vails A, Romeu A, Buendia E: CD23 expression on B-lymphocytes and its modulation by cvtokines in allergic patients, Clin Exp Allergy 1993:23:612-617.
16. Gagro A, Rabatic S: Allergen-induced CD23 on CD4+ T lymphocytes and CD21 on B lymphocytes in patients with allergic asthma: Evidence and regulation, Eur J Immunol 1994;24:1109-1114.
17. Sont JK, Booms P, Bel EH, Vandenbroucke JP, Slerk PJ: The determinants of airway hyperresponsiveness to hypertonic saline in atopic asthma in vivo, Relationship with sub-populations of peripheral blood leukocytes, Clin Exp Allergy 1993:23:678-688.
18. Walker C, Kaegi MK, Braun P, Blaser K: Activated T cells and eosinophilia in bronchoalveolar lavages from subjects with asthma correlated with disease severity, J Allergy Clin Immunol 1991:88:935-942.
19. Bradley BL, Azzawi M, Jacobson M, Assoufi LB, Collins JV, Irani AM, Schwartz LB, Durham SR, Jelfery PK, Kay AB: Eosinophils, T-lymphocytes, mast cell, neutrophils, and macrophages in bronchial biopsy specimens from atopic subjects with asthma: Comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship to bronchial hyperresponsiveness, J Allergy Clin Immunol 1991;88:661-674.