A unified total synthesis of the immunomodulators (-)-rapamycin and (-)-27-demethoxyrapamycin: Assembly of the common C(1-20) perimeter and final elaboration

Journal of the American Chemical Society

Volumn 119, Issue 5, 1997, Pages 962-973

  Smith III, Amos B ^a   Condon, Stephen M ^a   McCauley, John A ^a   Leazer Jr , Johnnie L ^a   Leahy, James W ^a   Maleczka Jr , Robert E ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEMETHOXYRAPAMYCIN; IMMUNOMODULATING AGENT; RAPAMYCIN; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; DRUG SYNTHESIS; ENANTIOMER; IN VITRO STUDY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0031025358     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja963067o     Document Type: Article

References (79)

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