Metabolic adaptation of terminal ileal mucosa after construction of an ileoanal pouch

British Journal of Surgery

Volumn 84, Issue 1, 1997, Pages 71-73

  Chapman, M A S ^a,b   Hutton, M ^a   Grahn, M F ^a   Williams, N S ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b NOTTINGHAM CITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRIC ACID; GLUTAMINE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; FEMALE; FOLLOW UP; HUMAN; ILEOANAL ANASTOMOSIS; ILEUM MUCOSA; ILEUM POUCH; MALE; METABOLISM; PRIORITY JOURNAL; SURGICAL TECHNIQUE; ULCERATIVE COLITIS; UNITED KINGDOM;

ADULT; AGED; BUTYRIC ACID; BUTYRIC ACIDS; COLITIS, ULCERATIVE; FEMALE; GLUCOSE; GLUTAMINE; HUMANS; ILEUM; INTESTINAL MUCOSA; MALE; MIDDLE AGED; OXIDATION-REDUCTION; PROCTOCOLECTOMY, RESTORATIVE;

EID: 0031024745     PISSN: 00071323     EISSN: None     Source Type: Journal    
DOI: 10.1002/bjs.1800840127     Document Type: Article

References (30)

1. Williams NS. Restorative proctocolectomy is the first choice elective surgical treatment for ulcerative colitis. Br J Surg 1989; 76: 1109-10.
2. Williams NS, Johnston D. The current status of mucosal proctectomy and ileo-anal anastomosis in the surgical treatment of ulcerative colitis and adenomatous polyposis. Br J Surg 1985; 72: 159-68.
3. Pinkus LM, Windmueller HG. Phosphate-dependent glutaminase of small intestine: localization and role in intestinal glutamine metabolism. Arch Biochem Biophys 1977; 182: 506-17.
4. Windmueller HG, Spaeth AE. Identification of ketone bodies and glutamine as the major respiratory fuels in vivo for postabsorptive rat small intestine. J Biol Chem 1978; 253: 69-76.
5. Cummings JH. Short chain fatty acids in the human colon. Gut 1981; 22: 763-79.
6. Chapman MAS, Grahn MF, Hutton M, Williams NS. Butyrate metabolism in the terminal ileal mucosa of patients with ulcerative colitis. Br J Surg 1995; 82: 36-8.
7. Roediger WEW. Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man. Gut 1980; 21: 793-8.
8. Chapman MAS, Grahn MF, Boyle MA, Hutton M, Rogers J, Williams NS. Butyrate oxidation is impaired in the colonic mucosa of sufferers of quiescent ulcerative colitis. Gut 1994; 35: 73-6.
9. Finnie IA, Taylor BA, Rhodes JM. Ileal and colonic epithelial metabolism in quiescent ulcerative colitis: increased glutamine metabolism in distal colon but no defect in butyrate metabolism. Gut 1993; 34: 1552-8.
10. Clausen MR, Mortensen PB. Kinetic studies on colonocyte metabolism of short chain fatty acids and glucose in ulcerative colitis. Gut 1995; 37: 684-9.
11. Moat AG, Foster JW. General reactions of amino acids In: Microbial Physiology. 2nd ed. New York: Wiley-Interscience, 1988: 270-9.
12. Sagar PM, Holdsworth PJ, Godwin PG, Quirke P, Smith AN, Johnston D. Comparison of triplicated (S) and quadruplicated (W) pelvic ileal reservoirs. Studies on manovolumetry, fecal bacteriology, fecal volatile fatty acids, mucosal morphology, and functional results. Gastroenterology 1992; 102: 520-8.
13. Chapman MAS, Grahn MF, Giamundo P et al. New technique to measure mucosal metabolism and its use to map substrate utilization in the healthy human large bowel. Br J Surg 1993; 80: 445-9.
14. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the folin phenol reagent. J Biol Chem 1951; 193: 265-75.
15. Chapman MAS. On human intestinal mucosal metabolism in health and disease. MS Thesis, University of London. 1995.
16. de Silva SH, Millard PR, Kettlewell M, Mortensen NJ, Prince C, Jewell DP. Mucosal characteristics of pelvic ileal pouches. Gut 1991; 32: 61-5.
17. de Silva SH, Millard PR, Soper N, Kettlewell M, Mortensen N, Jewell DP. Effects of the faecal stream and stasis on the ileal pouch mucosa. Gut 1991; 32: 1166-9.
18. Chapman MAS, Grahn MF, Williams NS. 5-Aminosalicylic acid increases colonic mucosal oxidation of glucose. Br J Surg 1993; 80: 648 (Abstract).
19. Ireland A, Jewell DP. 5-Aminosalicylic acid (5-ASA) has no effect on butyrate metabolism in human colonic epithelial cells. Gastroenterology 1990; 98: A176 (Abstract).
20. Nasmyth DG, Godwin PG, Dixon MF, Williams NS, Johnston D. Ileal ecology after pouch-anal anastomosis or ileostomy. A study of mucosal morphology, fecal bacteriology, fecal volatile fatty acids, and their inter-relationship. Gastroenterology 1989; 96: 817-24.
21. Shepherd NA, Jass JR, Duval I, Moskowitz RL, Nicholls RJ, Morson BC. Restorative proctocolectomy with ileal reservoir: pathological and histochemical study of mucosal biopsy specimens. J Clin Pathol 1987; 40: 601-7.
22. Madden MV, Farthing MJ, Nicholls RJ. Inflammation in ileal reservoirs: 'pouchitis'. Gut 1990; 31: 247-9.
23. Shepherd NA, Hulten L, Tytgat GN et al. Pouchitis. Int J Colorectal Dis 1989; 4: 205-29.
24. Rauh SM, Schoetz DJ Jr, Roberts PL, Murray JJ, Coller JA, Veidenheimer MC. Pouchitis - is it a wastebasket diagnosis? Dis Colon Rectum 1991; 34: 685-9.
25. Hosie K, Sachaguchi M, Tudor R, Gourevitch D, Kmiot D, Keighley MRB. Pouchitis after restorative proctocolectomy is associated with mucosal ischaemia. Gut 1989; 30: 1471-2 (Abstract).
26. O'Connell PR, Rankin DR, Weiland LH, Kelly KA. Enteric bacteriology, absorption, morphology and emptying after ileal pouch-anal anastomosis. Br J Surg 1986; 73: 909-14.
27. Nasmyth DG, Johnston D, Godwin PGR, Dixon MF, Smith A, Williams NS. Factors influencing bowel function after ileal pouch-anal anastomosis. Br J Surg 1986; 73: 469-73.
28. de Silva HJ, Ireland A, Kettlewell M, Mortensen N, Jewell DP. Short-chain fatty acid irrigation in severe pouchitis. N Engl J Med 1989; 321: 1416-17 (Letter).
29. Argenzio RA, Meuten DJ. Short-chain fatty acids induce reversible injury of porcine colon. Dig Dis Sci 1991; 36: 1459-68.
30. Wischmeyer P, Pemberton JH, Phillips SF. Chronic pouchitis after ileal pouch-anal anastomosis: responses to butyrate and glutamine suppositories in a pilot study. Mayo Clin Proc 1993; 68: 978-81.