Medications that may contribute to sexual disorders: A guide to assessment and treatment in family practice

Journal of Family Practice

Volumn 44, Issue 1, 1997, Pages 33-43

  Finger, William W ^a,c   Lund, Margaret ^b   Slagle, Mark A ^a  

^a James H Quillen VA Medical Center   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c Psychology Service 116B2   (United States)

Author keywords

abuse; disorders; drugs; Family; non prescription; practice; sex; street; substance

Indexed keywords

AMILORIDE; AMITRIPTYLINE; AMOXAPINE; ANTIHYPERTENSIVE AGENT; ATENOLOL; BENAZEPRIL; CHLORTALIDONE; CLOMIPRAMINE; CLONIDINE; DESIPRAMINE; DILTIAZEM; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; ENALAPRIL MALEATE; FLUOXETINE; FUROSEMIDE; GUANETHIDINE; HYDRALAZINE; HYDROCHLOROTHIAZIDE; METHYLDOPA; MINOXIDIL; NORTRIPTYLINE; PRAZOSIN; PROPRANOLOL; PROTRIPTYLINE; RESERPINE; SEROTONIN UPTAKE INHIBITOR; SPIRONOLACTONE; TRICYCLIC ANTIDEPRESSANT AGENT; UNINDEXED DRUG;

DEPRESSION; DIAGNOSTIC APPROACH ROUTE; HUMAN; HYPERTENSION; PRACTICE GUIDELINE; PRESCRIPTION; PRIAPISM; REVIEW; SEXUAL DYSFUNCTION;

ANTIHYPERTENSIVE AGENTS; DRUGS, NON-PRESCRIPTION; FAMILY PRACTICE; HUMANS; PSYCHOTROPIC DRUGS; SEXUAL DYSFUNCTION, PHYSIOLOGICAL; STREET DRUGS; SUBSTANCE-RELATED DISORDERS;

EID: 0031024652     PISSN: 00943509     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (51)

1. James B, Lord DJ. Human sexuality and medical education. Lancet 1976; 2:560-3.
2. Tanner LA, Hoff R, Carmichael LP. Teaching sex education, and counseling for the primary physician. South Med J 1976; 69:1591-4.
3. Matteson GN, Armstrong R, Kimes HM. Physician education in human sexuality. J Fam Pract 1984; 19:683-4.
4. Broekman CPM, Van Der Werff Ten Bosch JJ, Slob AK. An investigation into the management of patient with erection problems in general practice. Int J Impotence Res 1994; 6:67-72.
5. Courtenay, M. Sex problems in practice: what can a general practitioner do? BMJ 1981; 282:873-4.
6. Woosley RL, Flockhart D. A case for the development of Centers for Education and Research in Therapeutics (C.E.R.T.). Pharmacy Week 1995; 4(23):1-3.
7. Hubbard JR, Levenson JL, Patrick GA. Psychiatric side effects associated with the ten most commonly dispensed prescription drugs: a review. J Fam Pract 1991; 33:177-89.
8. Soyka LF, Mattison, DR. Prescription drugs that affect male sexual functioning. Drug Therapy 1981; August:46-58.
9. Watts RJ. Sexual functioning, health beliefs, and compliance with high blood pressure medications. Nurs Res 1982; 31:278-83.
10. Kaplan HS. The evaluation of sexual disorders: psychological and medical aspects. New York, NY: Brunner/Mazel, 1984.
11. Segraves RT, Segraves KB. Aging and drug effects on male sexuality. In: Rosen RC, Leiblum SR, eds. Erectile disorders: assessment and treatment. New York, NY: The Guilford Press, 1992.
12. Colvin CL, Ryan ML. Drug induced sexual dysfunction. Micromedex 1996; 89:1-16.
13. Prichard BNC, Johnston A, Hill I. Bethanidine, guanethidine and methyldopa in treatment of hypertension: a within-patient comparison. BMJ 1968; 1:135.
14. Bulpitt CJ, Dollery CT. Side effects of hypotensive agents evaluated by a self-administered questionnaire. BMJ 1973; 3:485-90.
15. Chang SW, Fine R, Siegel D, Chesney M, Black D, Hulley SB. The impact of diuretic therapy on reported sexual function. Arch Intern Med 1991;151:2402-8.
16. Stessman J, Ben-Ishay D. Chlorthalidone-induced impotence. BMJ 1980; 281:714.
17. Hogan MJ, Wallin JD, Bauer RM. Antihypertensive therapy and male sexual dysfunction. Psychomatics 1980; 21:234-7.
18. Caminos-Torres R, Ma L, Snyder PJ. Gynecomastia and semen abnormalities induced by spironolactone in normal men. J Clin Endocrinol Metab 1977; 45:255-60.
19. Buffum J: Pharmacosexology: the effects of drugs on sexual function. A review. J Psychoactive Drugs 1982; 14:5-44.
20. Hodge RH, Harward MP, West MS, Krongaard-DeMong L, Kowal-Neeley MB. Sexual function of women taking antihypertensive agents: a comparative study. J Gen Intern Med 1991; 6:290-4.
21. Boyden TW, Nugent CA, Oligara T. Reserpine hydrochlorothiazide and pituitary-gonadal hormones in hypertensive patients. Eur J Clin Pharmacol 1980; 17:329-32.
22. Alexander WD, Evans JI. Side effects of methyldopa Br Med J 1975; 2:501.
23. Veterans Administration Cooperative Study Group on Antihypertensive Agents. Multiclinic controlled trial of bethanidine and guanethidine in severe hypertension. Circulation 1977; 55:519-25.
24. McMahon FG. Management of essential hypertension. New York, NY: Furtura Publishing, 1978:194.
25. Burnett WC, Chahine RA. Sexual dysfunction as a complication of propranolol therapy in men. Cardiovasc Med 1979; 4:811-5.
26. Medical Research Council Working Party on Mild to Moderate Hypertension. Adverse reactions to bendrofluazide and propranolol for the treatment of mild hypertension. Lancet 1981; 2:539-42.
27. Mann KV, Abbott EC, Gray JD, Thiebaux HJ, Belzer EG. Sexual dysfunction with beta-blocker therapy: more common than we think? Sexuality and Disability 1982; 5(2):67-77.
28. Segraves RT. Sexual side-effects of psychiatric drugs. Int J Psychiatry Med 1988; 18:243-52.
29. Monteiro WO, Noshirvani HF, Marks IM, Lelliott PT. Anorgasmia from clomipramine in obsessive-compulsive disorder. Br J Psychiatry 1987; 151:107.
30. Cooper-Smartt JD, Rodham R. A technique for surveying the side-effects of tricyclic drugs with reference to reported sexual effects. J Int Med Res 1973; 1:473.
31. Balon R. Antidepressants in the treatment of premature ejaculation. J Sex Marital Ther 1996; 22:85-96.
32. Saenz de Tejada I, Ware JC, Blanco R, Pittard JT, Nadig PW, Azadzoi KM, et al. Pathophysiology of prolonged penile erection associated with trazodone use. J Urol 1991; 145:60-4.
33. Munjack DJ, Crocker B. Alprazolam-induced ejaculatory inhibition. J Clin Psychopharmacol 1986; 6:57-8.
34. Uhde TW, Tancer ME, Shea CA. Sexual dysfunction related to alprazolam treatment of social phobia Am J Psychiatry 1988; 145:531.
35. Coates NE. Priapism associated with Buspar. South Med J 1990; 83:983.
36. Ghadirian AM, Annable L, Belanger MC. Lithium benzodiazepines and sexual function in bipolar patients. Am J Psychiatry 1992; 149:801-5.
37. Kowalski A, Stanley RO, Dennerstein L, Burrows G, Maguire KP. The sexual side-effects of antidepressant medication: a double-blind comparison of two antidepressants in a non-psychiatric population. Br J Psychiatry 1985;147:413-8.
38. Mattson RH. Comparison of carbamazepine phenobarbital phenytoin and primidone in partial and secondarily generalized tonic-clonic seizures. N Engl J Med 1985; 313:145.
39. Jensen RT, Collen MJ, Pandol SJ, Allende HD, Raufman JP, Bissonnette BM, et al. Cimetidine-induced impotence and breast changes in patients with gastric hypersecretory states. N Engl J Med 1983; 308:883.
40. Oliver MF, Heady JA, Morris JN, Cooper J. A cooperative trial in the primary prevention of ischaemic heart disease using clofibrate. Report from the Committee of Principal Investigators. Br Heart J 1978; 40:1069-118.
41. Hosea SW, Santaella ML, Brown EJ, Berger M, Katasha K, Frank MM. Long-term therapy of hereditary angioedema with danazol. Ann Intern Med 1980; 93:809.
42. Neri A, Zukerman S, Aygen M, Lidor Y, Kaufman H. The effect of longterm administration of digoxin on plasma androgens and sexual dysfunction. J Sex Marital Ther 1987; 13:58.
43. Snyder S, Karaca I, Salis PJ. Disulfiram and nocturnal penile tumescence in the chronic alcoholic. Biol Psychiatry 1981; 16:399.
44. Pont A, Graybill JR, Craven PC, Galgiani JN, Dismukes WE, Reitz RE, Stevens DA. High-dose ketoconazole therapy and adrenal and testicular function in humans. Arch Intern Med 1984; 144:2150-3.
45. The Coronary Drug Project Research Group. Clofibrate and niacin in coronary heart disease. JAMA 1975; 231:360-81.
46. Hirschkowitz M, Karacan I, Howell JW, Arcasoy MO, Williams RL. Nocturnal penile tumescence in cigarette smokers with erectile dysfunction. Urology 1992; 39:101-7.
47. Mannino DM, Klevens RM, Flanders WD. Cigarette smoking: an independent risk factor for impotence? Am J Epidemiol 1994; 140:1003-8.
48. Buffum J, Moser C. MDMA and human sexual function. J Psychoactive Drugs 1986; 18:355-9.
49. Van Arsdalen K, Wein AJ. Drugs and male sexual dysfunction. American Urological Association Update Series 1984; 3(34):1-7.
50. Wei N. Naproxen and ejaculatory dysfunction. Ann Intern Med 1980; 93:933.
51. Abramawicz M. Drugs that cause sexual dysfunction. Med Lett Drugs Ther 1987; 29:65-70.