Crk is required for apoptosis in Xenopus egg extracts

EMBO Journal

Volumn 16, Issue 2, 1997, Pages 230-241

  Evans, Erica K ^b   Lu, Wange ^a   Strum, Susan L ^b   Mayer, Bruce J ^a   Kornbluth, Sally ^b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Apoptosis; crk protein; Signaling; Xenopus

Indexed keywords

CELL PROTEIN; CRK PROTEIN; PHOSPHOTYROSINE; PROTEIN TYROSINE KINASE; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING SITE; CELL TYPE; CONTROLLED STUDY; ETIOLOGY; FEMALE; HOMEOSTASIS; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; SIGNAL TRANSDUCTION; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; CHICKENS; FEMALE; FUSION PROTEINS, BCR-ABL; HUMANS; MOLECULAR SEQUENCE DATA; OOCYTES; PHOSPHOTYROSINE; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-CRK; SEQUENCE ALIGNMENT; XENOPUS; XENOPUS PROTEINS;

ANIMALIA;

EID: 0031024613     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.2.230     Document Type: Article

References (53)

1. Bakhshi, A., Jensen, J.P., Goldman, R. Wright, J.J., McBride, O.W., Epstein, A.L. and Korsmeyer, S.J. (1985) Cloning the chromosomal breakpoint of the t(14:18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18. Cell, 41, 889-906.
2. Bellamy, C.O.C., Malcomson, R.D.G., Harrison, D.J. and Wyllie, A.H. (1995) Cell death in health and disease: the biology and regulation of apoptosis. Semin. Cancer Biol., 6, 3-16.
3. Birge, R.B., Fajardo, J.E., Reichman, C., Shoelson, S.E., Songyang, Z., Cantley, L.C. and Hanafusa, H. (1993) Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts. Mol. Cell. Biol., 13, 4648-4656.
4. Boldin, M.P., Goncharov, T.M., Goltsev, Y. and Wallach, D. (1996) Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1 and TNF receptor-induced cell death. Cell, 85, 803-816.
5. Chapman, R.S., Whetton, A.D. and Dive, C. (1994) The suppression of drug-induced apoptosis by activation of v-ABL protein tyrosine kinase. Cancer Res., 54, 5131-5137.
6. Chinnaiyan, A.M. and Dixit, V.M. (1996) The cell-death machine. Curr. Biol., 6, 555-562.
7. Chittenden, T., Harrington, E.A., O'Connor, R., Flemington, C., Lutz, R.G., Evan, G.I. and Guild, B.C. (1995) Induction of apoptosis by the Bcl-2 homologue Bak. Nature, 374, 733-736.
8. Cleary, M.L., Smith, S.D. and Sklar, J. (1986) Cloning and structural analysis of cDNAs for bcl-2 and hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation. Cell, 47, 19-28.
9. Cohen, G.B., Ren, R. and Baltimore, D. (1995) Modular binding domains in signal transduction proteins. Cell, 80, 237-248.
10. Cortez, D., Kadlec, L. and Pendergast, A.M. (1995) Structural signaling requirements for BCR-Abl mediated transformation and inhibition of apoptosis. Mol. Cell. Biol., 15, 5531-5541.
11. Cosulich, S.C., Green, G. and Clarke, P.R. (1996) Bcl-2 regulates activation of apoptotic proteases in a cell-free system. Curr. Biol., 6, 997-1005.
12. Ellis, R.E., Yuan, J. and. Horvitz, H.R. (1991) Mechanisms and functions of cell death. Annu. Rev. Cell Biol., 7, 663-698.
13. Farrow, S.N., White, J.H.M., Martinou, I., Raven, T., Pun, K.-T., Grinham, C.J., Martinou, J.-C. and Brown, R. (1995) Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K. Nature, 374, 731-733.
14. Feller, S.M., Knudsen, B. and Hanafusa, H. (1994a) c-Abl kinase regulates the protein binding activity of c-Crk. EMBO J., 13, 2341-2351.
15. Feller, S.M., Ren, R., Hanafusa, H. and Baltimore, D. (1994b) SH2 and SH3 domains as molecular adhesives: the interactions of Crk and Abl. Trends Biochem. Sci., 19, 453-458.
16. Fernandez-Sarabia, M.J. and Bischoff, J.R. (1993) Bcl-2 associates with the ras-related protein R-ras p23. Nature, 366, 274-275.
17. Frisch, S.M., Vuori, K., Ruoslahti, E. and Chan-Hui, P.-Y. (1996) Control of adhesion-dependent cell survival by focal adhesion kinase. J. Cell Biol., 134, 791-799.
18. Gulbins, E. et al. (1995) FAS-induced apoptosis is mediated via a ceramide-initated RAS signaling pathway. Immunity, 2, 341-351.
19. Hockenberry, D., Nunez, G., Milliman, C., Schreiber, R.D. and Korsmeyer, S. (1990) Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature, 348, 334-336.
20. Hsueh, A.J., Billig, H., Tsafriri, A. (1994) Ovarian follicular atresia: a hormonally controlled apoptotic process. Endocrinol. Rev., 15, 707-724.
21. Kiefer, M.C., Brauer, M.J., Powers, V.C., Wu, J.J., Umansky, S.R., Tomei, L.D. and Barr, P.J. (1995) Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak. Nature, 374, 736-739.
22. Knudsen, B., Feller, S. and Hanafusa, H. (1994) Four proline-rich sequences of the guanine-nucleotide exchange factor C3G bind with unique specificity to the first Src homology 3 domain of Crk. J. Biol. Chem., 269, 32781-32787.
23. Liu, X., Kim, C.N., Yang, J., Jemmerson, R. and Wang, X. (1996) Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell, 86, 147-157.
24. Liu, Y., Bhalla, K., Hill, C. and Priest, D. (1994) Evidence for involvement of tyrosine phosphorylation in taxol-induced apoptosis in a human ovarian tumor cell line. Biochem. Pharmacol., 48, 1265-1272.
25. Matsuda, M., Tanaka, S., Nagata, S., Kojima, A., Kurata, T. and Shibuya, M. (1992) Two species of human CRKs cDNA encode proteins with distinct biological activities. Mol. Cell. Biol., 12, 3482-3489.
26. Matsuda, M., Hashimoto, Y., Muroya, K., Hasegawa, H., Kurata, T., Tanaka, S., Nakamura, S. and Hattori, S. (1994) CRK protein binds to two guanine nucleotide-releasing proteins for the ras family and modulates nerve growth factor-induced activation of ras in PC12 cells. Mol. Cell. Biol., 14, 5495-5500.
27. Mayer, B.J. and Hanafusa, H. (1990) Mutagenic analysis of the v-crk oncogene: requirement for SH2 and SH3 domains and correlation between increased cellular phosphotyrosine and transformation. J. Virol., 64, 3581-3589.
28. Mayer, B.J., Hamaguchi, M. and Hanafusa, H. (1988) A novel viral oncogene with structural similarity to phospholipase C. Nature, 332, 272-275.
29. McGahon, A., Nishioka, W.K., Martin, S.J., Mahboubi, A., Cotter, T.G. and Green, D.R. (1995) Regulation of the Fas apoptotic cell death pathway by Abl. J. Biol. Chem., 270, 22625-22631.
30. Migita, K., Eguchi, K., Kawabe, Y., Mizokami, A., Tsukada, T. and Nagataki, S. (1994) Prevention of anti-CD3 monoclonal antibody-induced thymic apoptosis by protein tyrosine kinase inhibitors. J. Immunol., 153, 3457-3465.
31. Muzio, M.A. et al. (1996) FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95(Fas/APO-1) death-inducing signaling complex. Cell, 85, 817-828.
32. Newmeyer, D.D., Farschon, D.M. and Reed, J.C. (1994) Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria. Cell, 79, 353-364.
33. Nichols, G., Raines, M., Vera, J., Lacomis, L., Tempst, P. and Golde, D. (1994) Identification of CRKL as the constitutively phosphorylated 39-kD tyrosine phosphoprotein in chronic myelogenous leukemia cells. Blood, 84, 2912-2918.
34. Oltavi, Z.N., Millman, C.L. and Korsmeyer, S.J. (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell, 74, 604-619.
35. Owen-Lynch, P.J., Wong, A.K.Y. and Whetton, A.D. (1995) v-Abl-mediated apoptotic suppression is associated with SHC phosphorylation without concomitant mitogen-activated protein kinase activation. J. Biol. Chem., 270, 5956-5962.
36. Pawson, T. (1995) Protein modules and signalling networks. Nature, 373, 573-579.
37. Reichman, C.T., Mayer, B.J., Keshav, S. and Hanafusa, H. (1992) The product of the cellular crk gene consists primarily of SH2 and SH3 regions. Cell Growth Differ., 3, 451-460.
38. Ribon, V., Hubbell, S., Herrera, R. and Saltiel, A.R. (1995) The product of the cbl oncogene forms stable complexes with endogenous crk in a tyrosine phosphorylation-dependent manner. Mol. Cell. Biol., 6, 45-52.
39. Rosen, M.K., Yamazaki, T., Gish, G.D., Day, C.M., Pawson, T. and Kay, L.E. (1995) Direct demonstration of an intramolecular Sh2-phosphotyrosine interaction in the crk protein. Nature, 374, 477-479.
40. Salgia, R. et al. (1995) Molecular cloning of paxillin, a focal adhesion phosphoprotein involved in growth factor receptor and oncogene signal transduction in hematopoietic cells. J. Biol. Chem., 270, 5039-5047.
41. Sato, T., Irie, S., Kitada, S. and Reed, J. (1995) FAP-1: a protein tyrosine phosphatase that associates with Fas. Science, 268, 411-415.
42. Schaller, M.D. and Parsons, J.T. (1995) pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk. Mol. Cell. Biol., 15, 2635-2645.
43. Schieven, G., Wahl, A.F., Myrdal, S., Grosmaire, L. and Ledbetter, J. (1995) Lineage-specific induction of B cell apoptosis and altered signal transduction by the phosphotyrosine phosphatase inhibitor Bis(maltolato)oxovanadium (IV). J. Biol. Chem., 270, 20824-20831.
44. Songyang, Z. et al. (1993) SH2 domains recognize specific phosphopeptide sequences. Cell, 72, 767-778.
45. Steller, H. (1995) Mechanisms and genes of cellular suicide. Science, 267, 1445-1449.
46. Su, X., Zhou, T., Wang, Z., Yang, P., Jope, R.S. and Mountz, J.D. (1995) Defective expression of hematopoietic cell protein tyrosine phosphatase (HCP) in lymphoid cells blocks Fas-mediated apoptosis. Immunity, 2, 353-362.
47. Tanaka, M., Gupta, R. and Mayer, B.J. (1996) Differential inhibition of signaling pathways by dominant-negative SH2/SH3 adapter proteins. Mol. Cell. Biol., 15, 6829-6837.
48. Tanaka, S. et al. (1994) C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins. Proc. Natl Acad. Sci. USA, 91, 3443-3447.
49. Tilly, J.L., Kowalski, K.I., Johnson, A.L. and Hsueh, A.J.W. (1991) Involvement of apoptosis in ovarian follicular atresia and postovulatory regression. Endocrinology, 129, 2799-2801.
50. Vaux, D.L., Weissman, I.L. and Kim, S.K. (1992) Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2. Nature, 258, 1955-1957.
51. cas signaling complex formation upon integrin-mediated cell adhesion: a role for src family kinases. Mol. Cell. Biol., 16, 2606-2613.
52. Wang, H., Millan, J., Cox, A., Der, C., Rapp, U., Beck, T., Zha, H. and Reed, J. (1995) R-ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism. J. Cell Biol., 129, 1103-1114.
53. Yousefi, S., Green, D.R., Blaser, K. and Simon, H.-U. (1994) Protein-tyrosine phophorylation regulates apoptosis in human eosinophils and neutrophils. Proc. Natl Acad. Sci. USA, 91, 10868-10872.