Differential effects of sex hormones on autoantibody production and proteinuria in chronic graft-versus-host disease-induced experimental lupus nephritis

Clinical and Experimental Immunology

Volumn 107, Issue 2, 1997, Pages 254-260

  Van Griensven, M ^a   Bergijk, E C ^a   Baelde, J J ^a   De Heer, E ^a   Bruijn, J A ^a,b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

autoimmunity; glomerulosclerosis; graft versus host disease; lupus nephritis; sex hormones

Indexed keywords

17BETA ETHYNYLESTRADIOL; AUTOANTIBODY; SEX HORMONE; TESTOSTERONE DECANOATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; ETIOLOGY; FEMALE; GLOMERULONEPHRITIS; LUPUS ERYTHEMATOSUS NEPHRITIS; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PROTEINURIA; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0031024607     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.1997.261-ce1141.x     Document Type: Article

References (41)

1. Treurniet RA, Bergijk EC, Baelde JJ, De Heer E, Hoedemaeker PhJ, Bruijn JA. Gender-related influences on the development of chronic graft-vs.-host disease-induced experimental lupus nephritis. Clin Exp Immunol 1993; 91:442-8.
2. Schuurs AHWM, Verheul HAM. Effects of gender and sex steroids on the immune response. J Steroid Biochem 1990; 35:157-72.
3. Beeson PB. Age and sex associations of 40 autoimmune diseases. Am J Med 1994; 96:457-62.
4. Lahita RG, Bradlow HL, Kunkel HG, Fishman J. Increased oxidation of testosterone in systemic lupus erythematosus. Arthritis Rheum 1983; 26:1517-21.
5. Lahita RG, Bradlow HL, Ginzler E, Pang S. Low plasma androgens in women with systemic lupus erythematosus. Arthritis Rheum 1987; 30:241-8.
6. Bruijn JA, Bergijk EC, De Heer E, Fleuren GJ, Hoedemaeker PhJ. Induction and progression of experimental lupus nephritis: exploration of a pathogenetic pathway. Kidney Int 1992; 41:5-13.
7. Rang HP, Dale MM. The reproductive system. In: Pharmacology. Edinburgh: Churchill Livingstone, 1991:532-56.
8. Verheul HAM, Stimson WH, Den Hollander FC, Schuurs AHWM. The effects of nandrolone, testosterone and their decanoate esters on murine lupus. Clin Exp Immunol 1981; 44:11-17.
9. Bergijk EC, Munaut C, Baelde JJ, Prins F, Foidart JM, Hoedemaeker PhJ, Bruijn JA. A histologic study of the extracellular matrix during the development of glomerulosclerosis in murine chronic graft-vs.-host disease. Am J Pathol 1992; 140:1147-56.
10. Bruijn JA, Elven EH, Hogendoorn PCW, Corver WE, Hoedemaeker PhJ, Fleuren GJ. Murine chronic graft-vs.-host disease as a model for lupus nephritis. Am J Pathol 1988; 130:639-41.
11. Bruijn JA, Hogendoorn PCW, Corver WE, Van den Broek LJCM, Hoedemaeker PhJ, Fleuren GJ. Pathogenesis of experimental lupus nephritis: a role for anti-basement membrane and anti-tubular brush border antibodies in murine chronic graft-vs.-host disease. Clin Exp Immunol 1990; 79:115-22.
12. Boon ME, Tabbers-Boumeester ML. Gynaecological cytology; a textbook and atlas. London: The Macmillan Press Ltd, 1980:3-200.
13. Junqueira LC, Cameiro J, Kelley RO. Mannelijk genitaalstelsel. In: James J, Langevoort HL, eds. Basic histology (Functionele histologie). Utrecht: Wetenschappelijke Uitgeverij Bunge, 1990:560-81.
14. Fishman J, Martucci C. Biological properties of 16a-hydroxyestrone: implications in estrogen physiology and pathophysiology. J Clin Endocrinol Metab 1980; 51:611-5.
15. Kramers K, Hylkema M, Termaat RM, Brinkman K, Smeenk R, Berden J. Histones in lupus nephritis. Exp Nephrol 1993; 1:224-8.
16. Yamamoto T, Nagase M, Hishida A, Honda N. Specific increases in urinary excretion of anti-DNA antibodies in lupus mice induced by lysozyme administration: further evidence for DNA-anti-DNA immune complexes in the pathogenesis of nephritis. Clin Exp Immunol 1993; 91:115-20.
17. Bowman C, Peters DK, Lockwood CM. Anti-glomerular basement membrane autoantibodies in the brown Norway rat: detection by a solid-phase radioimmunoassay. J Immunol Methods 1983; 61: 325-33.
18. Baelde JJ, Bergijk EC, Bruijn JA. Isolation and characterization of mouse glomerular basement membrane. J Clin Lab Immunol 1990; 33:17-20.
19. Julkunen HA. Oral contraceptives in systemic lupus erythematosus: side-effects and influence on the activity of SLE. Scand J Rheumatol 1991; 20:427-33.
20. Blank M, Mendlovic S, Fricke H, Mozes E, Talal N, Shoenfeld Y. Sex hormone involvement in the induction of experimental systemic lupus erythematosus by a pathogenic anti-DNA idiotype in naive mice. J Rheumatol 1990; 17:311-7.
21. 1 mice. J Exp Med 1978; 147:1568-83.
22. Roubinian JR, Talal N, Siiteri PK, Sadakian JA. Sex hormone modulation of autoimmunity in NZB/NZW mice. Arthritis Rheum 1979; 22:1162-9.
23. Raveche ES, Tjio JH, Boegel W, Steinberg AD. Studies of the effects of sex hormones on autosomal and X-linked genetic control of induced and spontaneous antibody production. Arthritis Rheum 1979; 22: 1177-87.
24. Shear HL, Roubinian JR, Gil P, Talal N. Clearance of sensitized erythrocytes in NZB/NZW mice. Effects of castration and sex hormone treatment. Eur J Immunol 1981; 11:776-80.
25. Carlsten H, Tarkowski A. Histocompatibility complex gene products and exposure to oestrogen: two independent disease accelerating factors in murine lupus. Scand J Immunol 1993; 38:341-7.
26. Makino M, Fujiwara M, Watanabe H. Studies on the mechanisms of the development of lupus nephritis in BXSB mice I. Analysis of immunological abnormalities at the onset period. J Clin Lab Immunol 1987; 22:127-31.
27. Lambert PH, Dixon FJ. Pathogenesis of the glomerulonephritis of NZB/W mice. J Exp Med 1968; 127:507-22.
28. Bruijn JA, van Leer EHG, Baelde JJ, Corver WE, Hogendoorn PCW, Fleuren GJ. Characterization and in vivo transfer of nephritogenic autoantibodies directed against dipeptidyl peptidase IV and laminin in experimental lupus nephritis. Lab Invest 1990; 63:350-9.
29. Aten J, Stet RJM, Wagenaar-Hilbers JPA, Weening JJ, Fleuren GJ, Nieuwenhuis P. Glomerulopathy induced by graft-vs.-host reaction in the rat. Scand J Immunol 1992; 35:93-105.
30. Aten J, Veninga A, Bruijn JA, Prins FA, De Heer E, Weening JJ. Antigenic specificities of glomerular-bound autoantibodies in membranous glomerulopathy induced by mercuric chloride. Clin Immunol Immunopathol 1992; 63:89-102.
31. 2-induced membranous glomerulopathy. Am J Pathol 1995; 146:1467-80.
32. Murphy ED, Roths JB. A Y chromosome associated factor in strain BXSB producing accelerated autoimmunity and lymphoproliferation. Arthritis Rheum 1979; 22:1188-94.
33. Bergijk EC, Baelde JJ, De Heer E, Killen PD, Bruijn JA. Differential mRNA and protein expression of collagen type IV subchains in experimental glomerulosclerosis. JASN 1995; 6:892 (Abstr.).
34. Kootstra CJ, Bergijk EC, Veninga A, Prins FA, De Heer E, Abrahamson DR, Bruijn JA. Qualitative alterations in laminin expression in experimental lupus nephritis. Am J Pathol 1995; 147:476-88.
35. McGowan KA, Kleinman HK, Schnaper HW. Expression of mRNA for extracellular matrix (ECM) proteases and their inhibitors by migrating endothelial cells: augmention of responses by estrogen. JASN 1994; 5:813.
36. Stryer L. Hormone action. In: Biochemistry. New York: W.H. Freeman and Co., 1988:975-1004.
37. Latchman DS. Transcription-factor mutations and disease. NEJM 1996; 334:28-33.
38. Neugarten J, Silbiger SR. Effects of sex hormones on mesangial cells. Am J Kid Dis 1995; 26:147-51.
39. Jean-Faucher Ch, Berger M, Gallon Ch, de Turckheim M, Veyssiere G, Jean Cl. Sex-related differences in renal size in mice: ontogeny and influence of neonatal androgens. J Endocr 1987; 115:241-6.
40. Blantz RC, Peterson OW, Blantz ER, Wilson CB. Sexual differences in glomerular ultrafiltration: effect of androgen administration in ovariectomized rats. Endocrinology 1988; 122:767-73.
41. 1 mice: accelerated autoimmune disease with normal circulating testosterone. Clin Immunol Immunopathol 1994; 71:338-43.